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Open Access 01-12-2014 | Letter to the Editor

Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population

Authors: Mengyuan Kan, Fatao Liu, Xiaoling Weng, Junyi Ye, Ting Wang, Mingqing Xu, Lin He, Yun Liu

Published in: Diagnostic Pathology | Issue 1/2014

Abstract

A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene SOD2, rs1789110 near the gene MBP and rs722782 near the gene C8orf42) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent population. We investigated the correlation between these variants and advanced age-related macular degeneration for the first time in a Han Chinese cohort; however, no evidence supports these previously identified loci contribute to advanced age-related macular degeneration susceptibility in Chinese population.

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Title: Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population
Authors: Mengyuan Kan
Fatao Liu
Xiaoling Weng
Junyi Ye
Ting Wang
Mingqing Xu
Lin He
Yun Liu
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Diagnostic Pathology / Issue 1/2014
Electronic ISSN: 1746-1596
DOI: https://doi.org/10.1186/1746-1596-9-73

At a glance: The STEP trials

Springer Medicine

Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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