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Tumor Biology
Published in: Tumor Biology 7/2014

01-07-2014 | Research Article

Association of periodontal disease with oral cancer: a meta-analysis

Authors: Qi-Wei Yao, Dong-Sheng Zhou, Hong-Juan Peng, Ping Ji, De-Sheng Liu

Published in: Tumor Biology | Issue 7/2014

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Abstract

The objective is to evaluate the association of periodontal disease with the risk of oral cancer. Literature retrieval, selection and assessment, data extraction, and meta-analyses were performed according to the RevMan 5.0 guidelines. In the meta-analysis, we utilized random-effect model to pool the odds ratio (OR) according to the test of heterogeneity. A total of five eligible studies included 1,191 oral cancer patients and 1,992 healthy control subjects were analyzed. By meta-analysis, we found a significant association of periodontal disease with oral cancer [OR = 3.53, 95 % CI (1.52–8.23); P = 0.003]. Patients with periodontal disease have increased susceptibility to oral cancer.
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Metadata
Title
Association of periodontal disease with oral cancer: a meta-analysis
Authors
Qi-Wei Yao
Dong-Sheng Zhou
Hong-Juan Peng
Ping Ji
De-Sheng Liu
Publication date
01-07-2014
Publisher
Springer Netherlands
Published in
Tumor Biology / Issue 7/2014
Print ISSN: 1010-4283
Electronic ISSN: 1423-0380
DOI
https://doi.org/10.1007/s13277-014-1951-8

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