Skip to main content
Top
Published in: Pediatric Radiology 8/2012

01-08-2012 | Original Article

Association of initial CT findings with quality-of-life outcomes for traumatic brain injury in children

Authors: Jonathan O. Swanson, Monica S. Vavilala, Jin Wang, Sumit Pruthi, James Fink, Kenneth M. Jaffe, Dennis Durbin, Thomas Koepsell, Nancy Temkin, Frederick P. Rivara

Published in: Pediatric Radiology | Issue 8/2012

Login to get access

Abstract

Background

Traumatic brain injury (TBI) is a leading cause of acquired disability in children and adolescents.

Objective

To demonstrate the association between specific findings on initial noncontrast head CT and long-term outcomes in children who have suffered TBI.

Materials and methods

This was an IRB-approved prospective study of children ages 2–17 years treated in emergency departments for TBI and who underwent a head CT as part of the initial work-up (n = 347). The change in quality of life at 12 months after injury was measured by the PedsQL scale.

Results

Children with TBI who had intracranial injuries identified on the initial head CT had a significantly lower quality-of-life scores compared to children with TBI whose initial head CTs were normal. In multivariate analysis, children whose initial head CT scans demonstrated intraventricular hemorrhage, parenchymal injury, midline shift ≥5 mm, hemorrhagic shear injury, abnormal cisterns or subdural hematomas ≥3 mm had lower quality of life scores 1 year after injury than children whose initial CTs did not have these same injuries.

Conclusion

Associations exist between findings from the initial noncontrast head CT and quality of life score 12 months after injury in children with TBI.
Literature
1.
go back to reference Guice KS, Cassidy LD, Oldham KT (2007) Traumatic injury and children: a national assessment. J Trauma 63:S68–S80PubMedCrossRef Guice KS, Cassidy LD, Oldham KT (2007) Traumatic injury and children: a national assessment. J Trauma 63:S68–S80PubMedCrossRef
2.
go back to reference Odetola FO, Mann NC, Hansen KW et al (2010) Source of admission and outcomes for critically injured children in the mountain states. Arch Pediatr Adolesc Med 164:277–282PubMedCrossRef Odetola FO, Mann NC, Hansen KW et al (2010) Source of admission and outcomes for critically injured children in the mountain states. Arch Pediatr Adolesc Med 164:277–282PubMedCrossRef
3.
go back to reference Rivara FP, Koepsell TD, Wang J et al (2011) Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents. Pediatrics 128:e1129–e1138PubMedCrossRef Rivara FP, Koepsell TD, Wang J et al (2011) Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents. Pediatrics 128:e1129–e1138PubMedCrossRef
4.
go back to reference Maas AI, Hukkelhoven CW, Marshall LF et al (2005) Prediction of outcome in traumatic brain injury with computed tomographic characteristics: a comparison between the computed tomographic classification and combinations of computed tomographic predictors. Neurosurgery 57:1173–1182, discussion 1173–1182PubMedCrossRef Maas AI, Hukkelhoven CW, Marshall LF et al (2005) Prediction of outcome in traumatic brain injury with computed tomographic characteristics: a comparison between the computed tomographic classification and combinations of computed tomographic predictors. Neurosurgery 57:1173–1182, discussion 1173–1182PubMedCrossRef
5.
go back to reference Maas AI, Steyerberg EW, Butcher I et al (2007) Prognostic value of computerized tomography scan characteristics in traumatic brain injury: results from the IMPACT study. J Neurotrauma 24:303–314PubMedCrossRef Maas AI, Steyerberg EW, Butcher I et al (2007) Prognostic value of computerized tomography scan characteristics in traumatic brain injury: results from the IMPACT study. J Neurotrauma 24:303–314PubMedCrossRef
6.
go back to reference Marshall LF, Marshall SB, Klauber MR et al (1992) The diagnosis of head injury requires a classification based on computed axial tomography. J Neurotrauma 9(Suppl 1):S287–S292PubMed Marshall LF, Marshall SB, Klauber MR et al (1992) The diagnosis of head injury requires a classification based on computed axial tomography. J Neurotrauma 9(Suppl 1):S287–S292PubMed
7.
go back to reference Chun KA, Manley GT, Stiver SI et al (2010) Interobserver variability in the assessment of CT imaging features of traumatic brain injury. J Neurotrauma 27:325–330PubMedCrossRef Chun KA, Manley GT, Stiver SI et al (2010) Interobserver variability in the assessment of CT imaging features of traumatic brain injury. J Neurotrauma 27:325–330PubMedCrossRef
8.
go back to reference Balestreri M, Czosnyka M, Chatfield DA et al (2004) Predictive value of Glasgow Coma Scale after brain trauma: change in trend over the past ten years. J Neurol Neurosurg Psychiatr 75:161–162PubMed Balestreri M, Czosnyka M, Chatfield DA et al (2004) Predictive value of Glasgow Coma Scale after brain trauma: change in trend over the past ten years. J Neurol Neurosurg Psychiatr 75:161–162PubMed
9.
go back to reference Marr AL, Coronado VG (eds) (2004) Central nervous system injury surveillance data submission standards–2002. Dept. of Health and Human Services (US), Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta, GA Marr AL, Coronado VG (eds) (2004) Central nervous system injury surveillance data submission standards–2002. Dept. of Health and Human Services (US), Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta, GA
10.
11.
go back to reference Kilgo PD, Osler TM, Meredith W (2003) The worst injury predicts mortality outcome the best: rethinking the role of multiple injuries in trauma outcome scoring. J Trauma 55:599–606, discussion 606–607PubMedCrossRef Kilgo PD, Osler TM, Meredith W (2003) The worst injury predicts mortality outcome the best: rethinking the role of multiple injuries in trauma outcome scoring. J Trauma 55:599–606, discussion 606–607PubMedCrossRef
12.
go back to reference Varni JW, Seid M, Kurtin PS (2001) PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care 39:800–812PubMedCrossRef Varni JW, Seid M, Kurtin PS (2001) PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care 39:800–812PubMedCrossRef
13.
go back to reference WHO (2001) International classification of functioning, disability, and health. World Health Organization WHO (2001) International classification of functioning, disability, and health. World Health Organization
14.
go back to reference Mccarthy ML (2007) Measuring children’s health-related quality of life after trauma. J Trauma 63:S122–S129PubMedCrossRef Mccarthy ML (2007) Measuring children’s health-related quality of life after trauma. J Trauma 63:S122–S129PubMedCrossRef
15.
go back to reference McCarthy ML, MacKenzie EJ, Durbin DR et al (2005) The Pediatric Quality of Life Inventory: an evaluation of its reliability and validity for children with traumatic brain injury. Arch Phys Med Rehabil 86:1901–1909PubMedCrossRef McCarthy ML, MacKenzie EJ, Durbin DR et al (2005) The Pediatric Quality of Life Inventory: an evaluation of its reliability and validity for children with traumatic brain injury. Arch Phys Med Rehabil 86:1901–1909PubMedCrossRef
16.
go back to reference McCarthy ML, MacKenzie EJ, Durbin DR et al (2006) Health-related quality of life during the first year after traumatic brain injury. Arch Pediatr Adolesc Med 160:252–260PubMedCrossRef McCarthy ML, MacKenzie EJ, Durbin DR et al (2006) Health-related quality of life during the first year after traumatic brain injury. Arch Pediatr Adolesc Med 160:252–260PubMedCrossRef
17.
go back to reference Varni JW, Limbers CA (2009) The pediatric quality of life inventory: measuring pediatric health-related quality of life from the perspective of children and their parents. Pediatr Clin N Am 56:843–863CrossRef Varni JW, Limbers CA (2009) The pediatric quality of life inventory: measuring pediatric health-related quality of life from the perspective of children and their parents. Pediatr Clin N Am 56:843–863CrossRef
18.
go back to reference Suskauer SJ, Huisman TA (2009) Neuroimaging in pediatric traumatic brain injury: current and future predictors of functional outcome. Dev Disabil Res Rev 15:117–123PubMedCrossRef Suskauer SJ, Huisman TA (2009) Neuroimaging in pediatric traumatic brain injury: current and future predictors of functional outcome. Dev Disabil Res Rev 15:117–123PubMedCrossRef
19.
go back to reference Firsching R, Woischneck D, Klein S et al (2001) Classification of severe head injury based on magnetic resonance imaging. Acta Neurochir 143:263–271CrossRef Firsching R, Woischneck D, Klein S et al (2001) Classification of severe head injury based on magnetic resonance imaging. Acta Neurochir 143:263–271CrossRef
20.
go back to reference Topal NB, Hakyemez B, Erdogan C et al (2008) MR imaging in the detection of diffuse axonal injury with mild traumatic brain injury. Neurol Res 30:974–978PubMedCrossRef Topal NB, Hakyemez B, Erdogan C et al (2008) MR imaging in the detection of diffuse axonal injury with mild traumatic brain injury. Neurol Res 30:974–978PubMedCrossRef
21.
go back to reference van Dongen KJ, Braakman R, Gelpke GJ (1983) The prognostic value of computerized tomography in comatose head-injured patients. J Neurosurg 59:951–957PubMedCrossRef van Dongen KJ, Braakman R, Gelpke GJ (1983) The prognostic value of computerized tomography in comatose head-injured patients. J Neurosurg 59:951–957PubMedCrossRef
22.
go back to reference Englander J (2003) The association of early computed tomography scan findings and ambulation, self-care, and supervision needs at rehabilitation discharge and at 1 year after traumatic brain injury. Arch Phys Med Rehabil 84:214–220PubMedCrossRef Englander J (2003) The association of early computed tomography scan findings and ambulation, self-care, and supervision needs at rehabilitation discharge and at 1 year after traumatic brain injury. Arch Phys Med Rehabil 84:214–220PubMedCrossRef
23.
go back to reference Borg J, Holm L, Cassidy JD et al (2004) Diagnostic procedures in mild traumatic brain injury: results of the WHO collaborating centre task force on mild traumatic brain injury. J Rehabil Med 43:S61–S75CrossRef Borg J, Holm L, Cassidy JD et al (2004) Diagnostic procedures in mild traumatic brain injury: results of the WHO collaborating centre task force on mild traumatic brain injury. J Rehabil Med 43:S61–S75CrossRef
Metadata
Title
Association of initial CT findings with quality-of-life outcomes for traumatic brain injury in children
Authors
Jonathan O. Swanson
Monica S. Vavilala
Jin Wang
Sumit Pruthi
James Fink
Kenneth M. Jaffe
Dennis Durbin
Thomas Koepsell
Nancy Temkin
Frederick P. Rivara
Publication date
01-08-2012
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 8/2012
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-012-2372-8

Other articles of this Issue 8/2012

Pediatric Radiology 8/2012 Go to the issue