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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2016 | Poster presentation

Association between serum ferritin and liver iron concentration with cardiac iron in pediatric thalassemia major patients

Authors: Antonella Meloni, Maddalena Casale, Aldo Filosa, Maria Giovanna Neri, Lorella Pitrolo, Maria Paola Smacchia, Stefania Renne, Antonino Vallone, Vincenzo Positano, Alessia Pepe

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2016

Excerpt

Recently, the ability of LIC (liver iron concentration) and serum ferritin in predicting myocardial iron overload (MIO) has been challenged by magnetic Resonance Imaging (MRI) monitoring which demonstrated no or weak correlation between serum ferritin or LIC and MIO. Anyway, the role of this traditional markers could result particularly useful in pediatric population, where MRI assessment is difficult to carry out, because of early age, scarce collaboration or limited availability. So, we derived objective thresholds for these markers for predicting cardiac T2*<20 ms in pediatric patients. …

Title: Association between serum ferritin and liver iron concentration with cardiac iron in pediatric thalassemia major patients
Authors: Antonella Meloni
Maddalena Casale
Aldo Filosa
Maria Giovanna Neri
Lorella Pitrolo
Maria Paola Smacchia
Stefania Renne
Antonino Vallone
Vincenzo Positano
Alessia Pepe
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue Special Issue 1/2016
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/1532-429X-18-S1-P295

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Association between serum ferritin and liver iron concentration with cardiac iron in pediatric thalassemia major patients

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