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Published in: Pediatric Rheumatology 1/2007

Open Access 01-12-2007 | Case Report

Association between celiac sprue and cryopyrin associated autoinflammatory disorders: a case report

Authors: Marcus Shaker, Susan Edwards, Henry Chionuma, Eric Shamansky, Hal M Hoffman

Published in: Pediatric Rheumatology | Issue 1/2007

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Abstract

Cryopyrin-associated diseases may be characterized by rashes, fever, and sensorineural deafness, while celiac disease may present with symptoms of malabsorption and fatigue. Arthritis is seen in both conditions. We report a young child with histologically diagnosed celiac disease and a cryopyrinopathy.
Literature
1.
go back to reference Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001, 29 (3): 301-305. 10.1038/ng756.PubMedCentralCrossRefPubMed Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001, 29 (3): 301-305. 10.1038/ng756.PubMedCentralCrossRefPubMed
2.
go back to reference Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, Lachmann HJ, Bybee A, Gaudet R, Woo P: Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 2002, 46 (9): 2445-2452. 10.1002/art.10509.CrossRefPubMed Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, Lachmann HJ, Bybee A, Gaudet R, Woo P: Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 2002, 46 (9): 2445-2452. 10.1002/art.10509.CrossRefPubMed
4.
go back to reference Hawkins PN, Lachmann HJ, Aganna E, McDermott MF: Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 2004, 50 (2): 607-612. 10.1002/art.20033.CrossRefPubMed Hawkins PN, Lachmann HJ, Aganna E, McDermott MF: Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 2004, 50 (2): 607-612. 10.1002/art.20033.CrossRefPubMed
5.
go back to reference Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, Anderson JP, Wanderer AA, Firestein GS: Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet. 2004, 364 (9447): 1779-1785. 10.1016/S0140-6736(04)17401-1.PubMedCentralCrossRefPubMed Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, Anderson JP, Wanderer AA, Firestein GS: Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet. 2004, 364 (9447): 1779-1785. 10.1016/S0140-6736(04)17401-1.PubMedCentralCrossRefPubMed
6.
go back to reference Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, Bertin J, Coyle AJ, Galan JE, Askenase PW: Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity. 2006, 24 (3): 317-327. 10.1016/j.immuni.2006.02.004.CrossRefPubMed Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, Bertin J, Coyle AJ, Galan JE, Askenase PW: Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity. 2006, 24 (3): 317-327. 10.1016/j.immuni.2006.02.004.CrossRefPubMed
7.
go back to reference Ting JP, Kastner DL, Hoffman HM: CATERPILLERs, pyrin and hereditary immunological disorders. Nat Rev Immunol. 2006, 6 (3): 183-195. 10.1038/nri1788.CrossRefPubMed Ting JP, Kastner DL, Hoffman HM: CATERPILLERs, pyrin and hereditary immunological disorders. Nat Rev Immunol. 2006, 6 (3): 183-195. 10.1038/nri1788.CrossRefPubMed
8.
go back to reference Matysiak-Budnik T, Candalh C, Dugave C, Namane A, Cellier C, Cerf-Bensussan N, Heyman M: Alterations of the intestinal transport and processing of gliadin peptides in celiac disease. Gastroenterology. 2003, 125 (3): 696-707. 10.1016/S0016-5085(03)01049-7.CrossRefPubMed Matysiak-Budnik T, Candalh C, Dugave C, Namane A, Cellier C, Cerf-Bensussan N, Heyman M: Alterations of the intestinal transport and processing of gliadin peptides in celiac disease. Gastroenterology. 2003, 125 (3): 696-707. 10.1016/S0016-5085(03)01049-7.CrossRefPubMed
9.
go back to reference Stepniak D, Koning F: Celiac disease – sandwiched between innate and adaptive immunity. Hum Immunol. 2006, 67 (6): 460-468. 10.1016/j.humimm.2006.03.011.CrossRefPubMed Stepniak D, Koning F: Celiac disease – sandwiched between innate and adaptive immunity. Hum Immunol. 2006, 67 (6): 460-468. 10.1016/j.humimm.2006.03.011.CrossRefPubMed
Metadata
Title
Association between celiac sprue and cryopyrin associated autoinflammatory disorders: a case report
Authors
Marcus Shaker
Susan Edwards
Henry Chionuma
Eric Shamansky
Hal M Hoffman
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue 1/2007
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-5-12

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