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Published in: BMC Oral Health 1/2017

Open Access 01-12-2017 | Research article

Association among oral symptoms, oral health-related quality of life, and health-related quality of life in a sample of adults living with HIV/AIDS in Malaysia

Authors: Nurulasmak Mohamed, Norkhafizah Saddki, Azizah Yusoff, Anilawati Mat Jelani

Published in: BMC Oral Health | Issue 1/2017

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Abstract

Background

Health-related quality of life (HRQOL) is a multidimensional construct that refers to an individual’s self-perceived well-being. This study used the revised Wilson and Cleary HRQOL model to investigate the associations among oral symptoms, oral health-related quality of life (OHRQOL), and HRQOL of people living with HIV/AIDS (PLWHA) in Malaysia.

Methods

A total of 121 PLWHA receiving medical care in Kota Bharu (Kelantan, Malaysia) participated in this cross-sectional study. The Malay version of the short Oral Health Impact Profile (S-OHIP(M)) and the Malay version of the 36-item Medical Outcome Study Short Form (SF-36) were used to assess OHRQOL and HRQOL, respectively. A higher S-OHIP(M) score indicates greater oral impact and worse OHRQOL; a higher SF-36 score indicates better HRQOL. An additional structured self-administered questionnaire was used to obtain other variables of interest from the participants.

Results

Most participants had at least one oral symptom (69.4%), and the most common oral symptom was a cavitated tooth (55.4%). The prevalence of oral impacts was 33.9%, and the mean S-OHIP(M) score was 8.8 (SD = 7.92). The mean S-OHIP(M) score was significantly higher in participants who had toothaches, cavitated teeth, gum abscesses, and bad breath. In addition, participants with lower S-OHIP(M) scores had significantly higher scores in all SF-36 domains.

Conclusions

Our study provides evidence for an association among oral symptoms, OHRQOL, and HRQOL in PLWHA from Malaysia. In particular, the presence of oral symptoms was significantly associated with more severe oral impacts and poorer OHRQOL. The presence of less severe oral impacts was associated with a better HRQOL.
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Literature
1.
go back to reference UNAIDS. Global AIDS Update 2016. Geneva: UNAIDS; 2016. UNAIDS. Global AIDS Update 2016. Geneva: UNAIDS; 2016.
2.
go back to reference Ledergerber B, Egger M, Erard V, Weber R, Hirschel B, Furrer H, Battegay M, Vernazza P, Bernasconi E, Opravil M, et al. AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV cohort study. JAMA. 1999;282(23):2220–6.CrossRefPubMed Ledergerber B, Egger M, Erard V, Weber R, Hirschel B, Furrer H, Battegay M, Vernazza P, Bernasconi E, Opravil M, et al. AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV cohort study. JAMA. 1999;282(23):2220–6.CrossRefPubMed
3.
go back to reference Loutfy MR, Wu W, Letchumanan M, Bondy L, Antoniou T, Margolese S, Zhang Y, Rueda S, McGee F, Peck R, et al. Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral therapy. PLoS One. 2013;8(2):e55747.CrossRefPubMedPubMedCentral Loutfy MR, Wu W, Letchumanan M, Bondy L, Antoniou T, Margolese S, Zhang Y, Rueda S, McGee F, Peck R, et al. Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral therapy. PLoS One. 2013;8(2):e55747.CrossRefPubMedPubMedCentral
4.
go back to reference d’Arminio Monforte A, Sabin CA, Phillips A, Sterne J, May M, Justice A, Dabis F, Grabar S, Ledergerber B, Gill J, et al. The changing incidence of AIDS events in patients receiving highly active antiretroviral therapy. Arch Intern Med. 2005;165(4):416–23.CrossRefPubMed d’Arminio Monforte A, Sabin CA, Phillips A, Sterne J, May M, Justice A, Dabis F, Grabar S, Ledergerber B, Gill J, et al. The changing incidence of AIDS events in patients receiving highly active antiretroviral therapy. Arch Intern Med. 2005;165(4):416–23.CrossRefPubMed
5.
go back to reference Kaplan JE, Hanson D, Dworkin MS, Frederick T, Bertolli J, Lindegren ML, Holmberg S, Jones JL. Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy. Clin Infect Dis. 2000;30(Suppl 1):S5–14.CrossRefPubMed Kaplan JE, Hanson D, Dworkin MS, Frederick T, Bertolli J, Lindegren ML, Holmberg S, Jones JL. Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy. Clin Infect Dis. 2000;30(Suppl 1):S5–14.CrossRefPubMed
6.
go back to reference UNAIDS. AIDS by the numbers 2015. Geneva: UNAIDS; 2015. UNAIDS. AIDS by the numbers 2015. Geneva: UNAIDS; 2015.
7.
go back to reference Ministry of Health Malaysia. Global AIDS response progress. Report Malaysia 2015. Kuala Lumpur: Ministry of Health Malaysia; 2015. Ministry of Health Malaysia. Global AIDS response progress. Report Malaysia 2015. Kuala Lumpur: Ministry of Health Malaysia; 2015.
8.
go back to reference Grossman HA, Sullivan PS, Wu AW. Quality of life and HIV: current assessment tools and future directions for clinical practice. AIDS Read. 2003;12:583–97. Grossman HA, Sullivan PS, Wu AW. Quality of life and HIV: current assessment tools and future directions for clinical practice. AIDS Read. 2003;12:583–97.
9.
go back to reference Fayers PM, Machin D. Quality of life. The assessment, analysis and interpretation of patient-reported outcomes. 2nd edition. West Sussex: John Wiley & Sons Ltd; 2007. Fayers PM, Machin D. Quality of life. The assessment, analysis and interpretation of patient-reported outcomes. 2nd edition. West Sussex: John Wiley & Sons Ltd; 2007.
10.
go back to reference Bakas T, McLennon SM, Carpenter JS, Buelow JM, Otte JL, Hanna KM, Ellett ML, Hadler KA, Welch JL: Systematic review of health-related quality of life models. Health Qual Life Outcomes 2012, Nov 16;10:134. doi: 10.1186/1477-7525-10-134. Bakas T, McLennon SM, Carpenter JS, Buelow JM, Otte JL, Hanna KM, Ellett ML, Hadler KA, Welch JL: Systematic review of health-related quality of life models. Health Qual Life Outcomes 2012, Nov 16;10:134. doi: 10.​1186/​1477-7525-10-134.
11.
go back to reference Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes. JAMA. 1995;273(1):59–65.CrossRefPubMed Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes. JAMA. 1995;273(1):59–65.CrossRefPubMed
12.
go back to reference Ferrans CE, Zerwic JJ, Wilbur JE, Larson JL. Conceptual model of health-related quality of life. J Nurs Scholarsh. 2005;37(4):336–42.CrossRefPubMed Ferrans CE, Zerwic JJ, Wilbur JE, Larson JL. Conceptual model of health-related quality of life. J Nurs Scholarsh. 2005;37(4):336–42.CrossRefPubMed
14.
go back to reference Hasanah C, Zaliha A, Mahiran M. Factors influencing the quality of life in patients with HIV in Malaysia. Qual Life Res. 2011;20(1):91–100.CrossRefPubMed Hasanah C, Zaliha A, Mahiran M. Factors influencing the quality of life in patients with HIV in Malaysia. Qual Life Res. 2011;20(1):91–100.CrossRefPubMed
15.
go back to reference Rueda S, Raboud J, Mustard C, Bayoumi A, Lavis JN, Rourke SB. Employment status is associated with both physical and mental health quality of life in people living with HIV. AIDS Care. 2011;23(4):435–43.CrossRefPubMed Rueda S, Raboud J, Mustard C, Bayoumi A, Lavis JN, Rourke SB. Employment status is associated with both physical and mental health quality of life in people living with HIV. AIDS Care. 2011;23(4):435–43.CrossRefPubMed
16.
go back to reference Nojomi M, Anbary K, Ranjbar M. Health-related quality of life in patients with HIV/AIDS. Arch Iranian Med. 2008;11(6):608–12. Nojomi M, Anbary K, Ranjbar M. Health-related quality of life in patients with HIV/AIDS. Arch Iranian Med. 2008;11(6):608–12.
18.
go back to reference Murri R, Fantoni M, Del Borgo C, Visona R, Barracco A, Zambelli A, Testa L, Orchi N, Tozzi V, Bosco O, et al. Determinants of health-related quality of life in HIV-infected patients. AIDS Care. 2003;15(4):581–90.CrossRefPubMed Murri R, Fantoni M, Del Borgo C, Visona R, Barracco A, Zambelli A, Testa L, Orchi N, Tozzi V, Bosco O, et al. Determinants of health-related quality of life in HIV-infected patients. AIDS Care. 2003;15(4):581–90.CrossRefPubMed
19.
go back to reference Clayson DJ, Wild DJ, Quarterman P, Duprat-Lomon I, Kubin M, Coons SJ. A comparative review of health-related quality-of-life measures for use in HIV/AIDS clinical trials. PharmacoEconomics. 2006;24(8):751–65.CrossRefPubMed Clayson DJ, Wild DJ, Quarterman P, Duprat-Lomon I, Kubin M, Coons SJ. A comparative review of health-related quality-of-life measures for use in HIV/AIDS clinical trials. PharmacoEconomics. 2006;24(8):751–65.CrossRefPubMed
20.
go back to reference Greenspan JS, Greenspan D. The epidemiology of the oral lesions of HIV infection in the developed world. Oral Dis. 2002;8:34–9.CrossRefPubMed Greenspan JS, Greenspan D. The epidemiology of the oral lesions of HIV infection in the developed world. Oral Dis. 2002;8:34–9.CrossRefPubMed
21.
go back to reference Bhayat A, Yengopal V, Rudolph M. Predictive value of group I oral lesions for HIV infection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(5):720–3.CrossRefPubMed Bhayat A, Yengopal V, Rudolph M. Predictive value of group I oral lesions for HIV infection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(5):720–3.CrossRefPubMed
22.
go back to reference Aleixo RQ, Scherma AP, Guimarães G, Cortelli JR, Cortelli SC. DMFT index and oral mucosal lesions associated with HIV infection: cross-sectional study in Porto Velho, Amazonian region - Brazil. Braz J Infect Dis. 2010;14(5):449–56.CrossRefPubMed Aleixo RQ, Scherma AP, Guimarães G, Cortelli JR, Cortelli SC. DMFT index and oral mucosal lesions associated with HIV infection: cross-sectional study in Porto Velho, Amazonian region - Brazil. Braz J Infect Dis. 2010;14(5):449–56.CrossRefPubMed
23.
go back to reference Santo AE, Tagliaferro EP, Ambrosano GM, Meneghim MC, Pereira AC. Dental status of Portuguese HIV+ patients and related variables: a multivariate analysis. Oral Dis. 2010;16(2):176–84.CrossRefPubMed Santo AE, Tagliaferro EP, Ambrosano GM, Meneghim MC, Pereira AC. Dental status of Portuguese HIV+ patients and related variables: a multivariate analysis. Oral Dis. 2010;16(2):176–84.CrossRefPubMed
24.
go back to reference Robinson PG, Sheiham A, Challacombe SJ, Zakrzewska JM. The periodontal health of homosexual men with HIV infection: a controlled study. Oral Dis. 1996;2(1):45–52.CrossRefPubMed Robinson PG, Sheiham A, Challacombe SJ, Zakrzewska JM. The periodontal health of homosexual men with HIV infection: a controlled study. Oral Dis. 1996;2(1):45–52.CrossRefPubMed
25.
go back to reference Slade GD, Spencer AJ. Development and evaluation of the oral health impact profile. Community Dent Health. 1994;11(1):3–11.PubMed Slade GD, Spencer AJ. Development and evaluation of the oral health impact profile. Community Dent Health. 1994;11(1):3–11.PubMed
26.
go back to reference Locker D. Measuring oral health: a conceptual framework. Community Dent Health. 1988;5(1):3–18.PubMed Locker D. Measuring oral health: a conceptual framework. Community Dent Health. 1988;5(1):3–18.PubMed
27.
go back to reference Saub R, Locker D, Allison P. Derivation and validation of the short version of the Malaysian oral health impact profile. Community Dent Oral Epidemiol. 2005;33(5):378–83.CrossRefPubMed Saub R, Locker D, Allison P. Derivation and validation of the short version of the Malaysian oral health impact profile. Community Dent Oral Epidemiol. 2005;33(5):378–83.CrossRefPubMed
28.
go back to reference Sararaks S, Azman AB, Low LL, Rugayah B, Aziah AM, Hooi LN, Abdul Razak M, Norhaya MR, Lim KB, Azian AA, et al. Validity and reliability of the SF-36: the Malaysian context. Med J Malaysia. 2005;60(2):163–79.PubMed Sararaks S, Azman AB, Low LL, Rugayah B, Aziah AM, Hooi LN, Abdul Razak M, Norhaya MR, Lim KB, Azian AA, et al. Validity and reliability of the SF-36: the Malaysian context. Med J Malaysia. 2005;60(2):163–79.PubMed
29.
go back to reference Ware JE, Snow KK, Kosinski M, Gandek B. SF-36 health survey: manual and interpretation guide. Boston: The Health Institute, New England Medical Center; 1993. Ware JE, Snow KK, Kosinski M, Gandek B. SF-36 health survey: manual and interpretation guide. Boston: The Health Institute, New England Medical Center; 1993.
30.
go back to reference Azman AB, Sararaks S, Rugayah B, Low LL, Azian AA, Geeta S, Tiew CT. Quality of life of the Malaysian general population: results from a postal survey using the SF-36. Med J Malaysia. 2003;58(5):694–711.PubMed Azman AB, Sararaks S, Rugayah B, Low LL, Azian AA, Geeta S, Tiew CT. Quality of life of the Malaysian general population: results from a postal survey using the SF-36. Med J Malaysia. 2003;58(5):694–711.PubMed
31.
go back to reference de Quadros Coelho M, Cordeiro JM, Vargas AMD, de Barros Lima AME, Santa Rosa TTDA, Senna MIB, Ferreira RC. Functional and psychosocial impact of oral disorders and quality of life of people living with HIV/AIDS. Qual Life Res. 2015;24(2):503–11.CrossRefPubMed de Quadros Coelho M, Cordeiro JM, Vargas AMD, de Barros Lima AME, Santa Rosa TTDA, Senna MIB, Ferreira RC. Functional and psychosocial impact of oral disorders and quality of life of people living with HIV/AIDS. Qual Life Res. 2015;24(2):503–11.CrossRefPubMed
32.
go back to reference Liberali SA, Coates EA, Freeman AD, Logan RM, Jamieson L, Mejia G. Oral conditions and their social impact among HIV dental patients, 18 years on. Aust Dent J. 2013;58(1):18–25.CrossRefPubMed Liberali SA, Coates EA, Freeman AD, Logan RM, Jamieson L, Mejia G. Oral conditions and their social impact among HIV dental patients, 18 years on. Aust Dent J. 2013;58(1):18–25.CrossRefPubMed
33.
go back to reference Ministry of Health Malaysia. National Oral Health Survey of adults 2010. Kuala Lumpur: Oral Health Division, Ministry of Health Malaysia; 2013. Ministry of Health Malaysia. National Oral Health Survey of adults 2010. Kuala Lumpur: Oral Health Division, Ministry of Health Malaysia; 2013.
34.
go back to reference Saddki N, Yusoff A, Hwang YL. Factors associated with dental visit and barriers to utilisation of oral health care services in a sample of antenatal mothers in Hospital Universiti Sains Malaysia. BMC Public Health. 2010;10(1):75.CrossRefPubMedPubMedCentral Saddki N, Yusoff A, Hwang YL. Factors associated with dental visit and barriers to utilisation of oral health care services in a sample of antenatal mothers in Hospital Universiti Sains Malaysia. BMC Public Health. 2010;10(1):75.CrossRefPubMedPubMedCentral
35.
go back to reference Patton LL, Strauss RP, McKaig RG, Porter DR, Eron JJ. Perceived oral health status, unmet needs, and barriers to dental care among HIV/AIDS patients in a North Carolina cohort: impacts of race. J Public Health Dent. 2003;63(2):86–91.CrossRefPubMed Patton LL, Strauss RP, McKaig RG, Porter DR, Eron JJ. Perceived oral health status, unmet needs, and barriers to dental care among HIV/AIDS patients in a North Carolina cohort: impacts of race. J Public Health Dent. 2003;63(2):86–91.CrossRefPubMed
36.
go back to reference Jeanty Y, Cardenas G, Fox JE, Pereyra M, Diaz C, Bednarsh H, Reznik DA, Abel SN, Bachman SS, Metsch LR. Correlates of unmet dental care need among HIV-positive people since being diagnosed with HIV. Public Health Rep. 2012;127(Suppl 2):17–24.CrossRefPubMedPubMedCentral Jeanty Y, Cardenas G, Fox JE, Pereyra M, Diaz C, Bednarsh H, Reznik DA, Abel SN, Bachman SS, Metsch LR. Correlates of unmet dental care need among HIV-positive people since being diagnosed with HIV. Public Health Rep. 2012;127(Suppl 2):17–24.CrossRefPubMedPubMedCentral
38.
go back to reference Coulter ID, Heslin KC, Marcus M, Hays RD, Freed J, Der-Martirosian C, Guzman-Becerra N, Cunningham WE, Andersen RM, Shapiro MF. Associations of self-reported oral health with physical and mental health in a nationally representative sample of HIV persons receiving medical care. Qual Life Res. 2002;11(1):57–70.CrossRefPubMed Coulter ID, Heslin KC, Marcus M, Hays RD, Freed J, Der-Martirosian C, Guzman-Becerra N, Cunningham WE, Andersen RM, Shapiro MF. Associations of self-reported oral health with physical and mental health in a nationally representative sample of HIV persons receiving medical care. Qual Life Res. 2002;11(1):57–70.CrossRefPubMed
39.
go back to reference Jeganathan S, Batterham M, Begley K, Purnomo J, Houtzager L. Predictors of oral health quality of life in HIV-1 infected patients attending routine care in Australia. J Public Health Dent. 2011;71(3):248–51.PubMed Jeganathan S, Batterham M, Begley K, Purnomo J, Houtzager L. Predictors of oral health quality of life in HIV-1 infected patients attending routine care in Australia. J Public Health Dent. 2011;71(3):248–51.PubMed
40.
go back to reference Tomar SL, Pereyra M, Metsch LR. Oral health-related quality of life among low-income adults living with HIV. J Public Health Dent. 2011;71(3):241–7.PubMed Tomar SL, Pereyra M, Metsch LR. Oral health-related quality of life among low-income adults living with HIV. J Public Health Dent. 2011;71(3):241–7.PubMed
42.
go back to reference Palella FJ Jr, Baker RK, Moorman AC, Chmiel JS, Wood KC, Brooks JT, Holmberg SD, HIV Outpatient Study Investigators. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. J Acquir Immune Defic Syndr. 2006;43(1):27–34.CrossRefPubMed Palella FJ Jr, Baker RK, Moorman AC, Chmiel JS, Wood KC, Brooks JT, Holmberg SD, HIV Outpatient Study Investigators. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. J Acquir Immune Defic Syndr. 2006;43(1):27–34.CrossRefPubMed
43.
go back to reference Yang CH, Huang YF, Hsiao CF, Yeh YL, Liou HR, Hung CC, Yang SY. Trends of mortality and causes of death among HIV-infected patients in Taiwan, 1984-2005. HIV Med. 2008;9(7):535–43.CrossRefPubMed Yang CH, Huang YF, Hsiao CF, Yeh YL, Liou HR, Hung CC, Yang SY. Trends of mortality and causes of death among HIV-infected patients in Taiwan, 1984-2005. HIV Med. 2008;9(7):535–43.CrossRefPubMed
44.
go back to reference Fairall LR, Bachmann MO, Louwagie GM, van Vuuren C, Chikobvu P, Steyn D, Staniland GH, Timmerman V, Msimanga M, Seebregts CJ, et al. Effectiveness of antiretroviral treatment in a south African program: a cohort study. Arch Intern Med. 2008;168(1):86–93.CrossRefPubMed Fairall LR, Bachmann MO, Louwagie GM, van Vuuren C, Chikobvu P, Steyn D, Staniland GH, Timmerman V, Msimanga M, Seebregts CJ, et al. Effectiveness of antiretroviral treatment in a south African program: a cohort study. Arch Intern Med. 2008;168(1):86–93.CrossRefPubMed
45.
go back to reference Ramírez-Amador V, Esquivel-Pedraza L, Sierra-Madero J, Anaya-Saavedra G, González-Ramírez I, Ponce-de-León S. The changing clinical spectrum of human immunodeficiency virus (HIV)-related oral lesions in 1,000 consecutive patients: a 12-year study in a referral center in Mexico. Medicine (Baltimore). 2003;82(1):39–50.CrossRef Ramírez-Amador V, Esquivel-Pedraza L, Sierra-Madero J, Anaya-Saavedra G, González-Ramírez I, Ponce-de-León S. The changing clinical spectrum of human immunodeficiency virus (HIV)-related oral lesions in 1,000 consecutive patients: a 12-year study in a referral center in Mexico. Medicine (Baltimore). 2003;82(1):39–50.CrossRef
46.
go back to reference Miners A, Phillips A, Kreif N, Rodger A, Speakman A, Fisher M, Anderson J, Collins S, Hart G, Sherr L, et al. Health-related quality-of-life of people with HIV in the era of combination antiretroviral treatment: a cross-sectional comparison with the general population. Lancet HIV. 2014;1(1):e32–40.CrossRefPubMed Miners A, Phillips A, Kreif N, Rodger A, Speakman A, Fisher M, Anderson J, Collins S, Hart G, Sherr L, et al. Health-related quality-of-life of people with HIV in the era of combination antiretroviral treatment: a cross-sectional comparison with the general population. Lancet HIV. 2014;1(1):e32–40.CrossRefPubMed
47.
go back to reference Hays RD, Cunningham WE, Sherbourne CD, Wilson IB, Wu AW, Cleary PD, McCaffrey DF, Fleishman JA, Crystal S, Collins R, et al. Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV cost and services utilization study. Am J Med. 2000;108(9):714–22.CrossRefPubMed Hays RD, Cunningham WE, Sherbourne CD, Wilson IB, Wu AW, Cleary PD, McCaffrey DF, Fleishman JA, Crystal S, Collins R, et al. Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV cost and services utilization study. Am J Med. 2000;108(9):714–22.CrossRefPubMed
48.
go back to reference Jelsma J, Maclean E, Hughes J, Tinise X, Darder M. An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART. AIDS Care. 2005;17(5):579–88.CrossRefPubMed Jelsma J, Maclean E, Hughes J, Tinise X, Darder M. An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART. AIDS Care. 2005;17(5):579–88.CrossRefPubMed
49.
go back to reference Tomita A, Garrett N, Werner L, Burns JK, Ngcobo N, Zuma N, Mlisana K, van Loggerenberg F, Abdool Karim SS. Impact of antiretroviral therapy on health-related quality of life among south African women in the CAPRISA 002 acute infection study. AIDS Behav. 2014;18(9):1801–7.CrossRefPubMedPubMedCentral Tomita A, Garrett N, Werner L, Burns JK, Ngcobo N, Zuma N, Mlisana K, van Loggerenberg F, Abdool Karim SS. Impact of antiretroviral therapy on health-related quality of life among south African women in the CAPRISA 002 acute infection study. AIDS Behav. 2014;18(9):1801–7.CrossRefPubMedPubMedCentral
50.
go back to reference Saunders DS, Burgoyne RW. Evaluating health-related wellbeing outcomes among outpatient adults with human immunodeficiency virus infection in the HAART era. Int J STD AIDS. 2002;13(10):683–90.CrossRefPubMed Saunders DS, Burgoyne RW. Evaluating health-related wellbeing outcomes among outpatient adults with human immunodeficiency virus infection in the HAART era. Int J STD AIDS. 2002;13(10):683–90.CrossRefPubMed
51.
go back to reference Casado A, Badia X, Consiglio E, Ferrer E, González A, Pedrol E, Gatell JM, Azuaje C, Llibre JM, Aranda M, et al. Health-related quality of life in HIV-infected naive patients treated with nelfinavir or nevirapine associated with ZDV/3TC (the COMBINE-QoL substudy). HIV Clin Trials. 2004;5(3):132–9.CrossRefPubMed Casado A, Badia X, Consiglio E, Ferrer E, González A, Pedrol E, Gatell JM, Azuaje C, Llibre JM, Aranda M, et al. Health-related quality of life in HIV-infected naive patients treated with nelfinavir or nevirapine associated with ZDV/3TC (the COMBINE-QoL substudy). HIV Clin Trials. 2004;5(3):132–9.CrossRefPubMed
52.
go back to reference Liu C, Ostrow D, Detels R, Hu Z, Johnson L, Kingsley L, Jacobson LP. Impacts of HIV infection and HAART use on quality of life. Qual Life Res. 2006;15(6):941–9.CrossRefPubMed Liu C, Ostrow D, Detels R, Hu Z, Johnson L, Kingsley L, Jacobson LP. Impacts of HIV infection and HAART use on quality of life. Qual Life Res. 2006;15(6):941–9.CrossRefPubMed
57.
go back to reference Kamper SJ, Maher CG, Mackay G. Global rating of change scales: a review of strengths and weaknesses and considerations for design. J Man Manip Ther. 2009;17(3):163–70.CrossRefPubMedPubMedCentral Kamper SJ, Maher CG, Mackay G. Global rating of change scales: a review of strengths and weaknesses and considerations for design. J Man Manip Ther. 2009;17(3):163–70.CrossRefPubMedPubMedCentral
58.
go back to reference Degroote S, Vogelaers D, Vandijck DM. What determines health-related quality of life among people living with HIV: an updated review of the literature. Arch Public Health. 2014;72(1):40.CrossRefPubMedPubMedCentral Degroote S, Vogelaers D, Vandijck DM. What determines health-related quality of life among people living with HIV: an updated review of the literature. Arch Public Health. 2014;72(1):40.CrossRefPubMedPubMedCentral
59.
go back to reference Shimada A, Sasaki Y, Mataki S. An evaluation of self-reported oral health and health-related quality of life. J Med Dent Sci. 2005;52(1):65–72.PubMed Shimada A, Sasaki Y, Mataki S. An evaluation of self-reported oral health and health-related quality of life. J Med Dent Sci. 2005;52(1):65–72.PubMed
60.
go back to reference Reissmann DR, John MT, Schierz O, Kriston L, Hinz A. Association between perceived oral and general health. J Dent. 2013;41(7):581–9.CrossRefPubMed Reissmann DR, John MT, Schierz O, Kriston L, Hinz A. Association between perceived oral and general health. J Dent. 2013;41(7):581–9.CrossRefPubMed
61.
go back to reference Zimmer S, Bergmann N, Gabrun E, Barthel C, Raab W, Rüffer J-U. Association between oral health-related and general health-related quality of life in subjects attending dental offices in Germany. J Public Health Dent. 2010;70(2):167–70.PubMed Zimmer S, Bergmann N, Gabrun E, Barthel C, Raab W, Rüffer J-U. Association between oral health-related and general health-related quality of life in subjects attending dental offices in Germany. J Public Health Dent. 2010;70(2):167–70.PubMed
Metadata
Title
Association among oral symptoms, oral health-related quality of life, and health-related quality of life in a sample of adults living with HIV/AIDS in Malaysia
Authors
Nurulasmak Mohamed
Norkhafizah Saddki
Azizah Yusoff
Anilawati Mat Jelani
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2017
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-017-0409-y

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