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01-12-2020 | ASO Author Reflections

ASO Author Reflections: Patient-Reported Outcomes—Bench to Bedside

Authors: Srinivas Joga Ivatury, MD, MHA, FACS, FASCRS, Sandra L. Wong, MD, MS, FACS, Deborah Schrag, MD, MPH

Published in: Annals of Surgical Oncology | Special Issue 3/2020

Excerpt

Historically, oncology trials have focused on quantitative parameters: mortality, recurrence, and short-term morbidity. In recent years, there has been a trend toward obtaining patient perspective through systematic tracking of electronic patient reported outcomes. PRO-CTCAE, a companion to CTCAE that measures symptomatic toxicity from the patient perspective, has been developed and validated and is publicly available for use in multiple languages.1,2 Recent oncology clinical trials that have utilized PROs have demonstrated reduced acute care utilization and symptom burden, as well as improved survival. It has now become imperative to translate and integrate PROs into everyday oncology clinical practice. …

Basch E, Reeve BB, Mitchell SA, et al. Development of the National Cancer Institute’s patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE). J Natl Cancer Inst. 2014;106(9):244.CrossRef

Basch E, Dueck AC, Rogak LJ, et al. Feasibility of implementing the patient-reported outcomes version of the common terminology criteria for adverse events in a multicenter trial: NCCTG N1048. J Clin Oncol. 2018;36(31):3120–5.CrossRef

Ivatury SJ, Hazard-Jenkins HW, Brooks GA, et al. Translation of patient-reported outcomes in oncology clinical trials to everyday practice. Ann Surg Oncol. 2019. https://doi.org/10.1245/s10434-019-07749-2.CrossRefPubMed

McCann L, Maguire R, Miller M, Kearney N. Patients’ perceptions and experiences of using a mobile phone-based advanced symptom management system (ASyMS©) to monitor and manage chemotherapy related toxicity. Eur J Cancer Care. 2009;18(2):156–64.CrossRef

Electronic Patient Reporting of Symptoms During Cancer Treatment (PRO-TECT). National Institutes of Health Clinical Trials.gov. https://clinicaltrials.gov/ct2/show/NCT03249090. Accessed 8 July 2019.

Improving the Management of Symptoms During and Following Cancer Treatment (IMPACT). National Cancer Institute: Division of Cancer Control and Population Sciences. https://healthcaredelivery.cancer.gov/impact. Accessed 8 July 2019.

Title: ASO Author Reflections: Patient-Reported Outcomes—Bench to Bedside
Authors: Srinivas Joga Ivatury, MD, MHA, FACS, FASCRS
Sandra L. Wong, MD, MS, FACS
Deborah Schrag, MD, MPH
Publication date: 01-12-2020
Publisher: Springer International Publishing
Published in: Annals of Surgical Oncology / Issue Special Issue 3/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-019-07920-9

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ASO Author Reflections: Patient-Reported Outcomes—Bench to Bedside

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