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Critical Care
Published in: Critical Care 1/2018

Open Access 01-12-2018 | Editorial

Artificial oxygen carriers: a new future?

Author: Donat R. Spahn

Published in: Critical Care | Issue 1/2018

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Excerpt

Despite the fact that allogeneic red blood cell (RBC) transfusions can be life-saving in exsanguinating trauma patients, many adverse events impacting patient outcome have documented [1]. Therefore, artificial oxygen carriers were initially been developed as “blood substitutes” in the 1980s and 1990s. Artificial oxygen carriers can be grouped into hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbon-based oxygen carriers (PFCs) [2]. …
Footnotes
1
https://www.prnewswire.com/news-releases/hemoglobin-oxygen-therapeutics-llc-announces-the-worlds-first-human-liver-transplantation-after-ex-situ-normothermic-machine-perfusion-using-hemopure-300538456.html
 
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Natanson C, Kern SJ, Lurie P, Banks SM, Wolfe SM. Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis. JAMA. 2008;299(19):2304–12.CrossRefPubMed
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Metadata
Title
Artificial oxygen carriers: a new future?
Author
Donat R. Spahn
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2018
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-018-1949-5

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