Issue Special Issue 3/2007
6thGlobal Arthritis Research Network (GARN) Meeting
Content (39 Articles)
IL-21 modulates cytokine levels in murine collagen-induced arthritis and contributes to disease pathology
DA Young, M Hegen, H Ma, L Napierata, J Lamothe, M Senices, L Lowe, M Collins, C Nickerson-Nutter
Combined anti-inflammatory tritherapy using a novel small interfering RNA lipoplex successfully prevents and cures mice of arthritis
M Khoury, V Escriou, A Galy, R Yao, C Largeau, D Scherman, C Jorgensen, F Apparailly
An integrative genomics strategy for the identification of collagen-induced arthritis susceptibility genes
Saleh M Ibrahim
Tumour necrosis factor-dependent inflammatory cartilage destruction
A Korb, B Tuerk, F Echtermeyer, T Pap, JS Smolen, K Redlich
Histidine deficiency does not protect against aggrecan-induced arthritis
Gyorgy Nagy, Marianna Csilla Holub, Karoly Németh, Maria Pasztoi, Mercedesz Mazan, Agnes Koncz, Andras Falus, Edit Buzas
Mast cells jump start K/BxN serum transfer arthritis via IL-1
PA Nigrovic, A Johnsen, BA Binstadt, PA Monach, M Gurish, Y Iwakura, D Mathis, C Benoist, DM Lee
Disrupting Mer receptor tyrosine kinase expression prevents autoimmune chronic graft-versus-host disease
Wen-Hai Shao, Robert A Eisenberg, Philip L Cohen
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from human marginal zone B cells as well as from circulating peripheral blood B cells from autoimmune patients
Rachel Ettinger, Stefan Kuchen, Gary P Sims, Rachel Robbins, David Withers, Randy T Fischer, Peter E Lipsky
IL-33: a novel cytokine with proinflammatory properties
Gaby Palmer, David Moulin, Olivier Donzé, Dominique Talabot-Ayer, Cem Gabay
Tolerogenic dendritic cells differentially modulate naïve and memory CD4+ T cells
Amy E Anderson, Bethan Sayers, Julie Diboll, John D Isaacs, Catharien MU Hilkens
Generation of dexamethasone and vitamin D3-treated human monocyte-derived dendritic cells with tolerogenic properties
Bethan Sayers, Muzlifah Haniffa, Julie Diboll, John Isaacs, Catharien Hilkens
Arthritis induced by systemic autoimmunity against glucose-6-phosphate isomerase in normal mice
T Kamradt, L Bruns, O Frey, L Morawietz, D Schubert, A Taubner
Regulation of eicosanoid production in peripheral blood mononuclear cells from patients with systemic sclerosis
Otylia Kowal-Bielecka, Krzysztof Kowal, Justyna Chwiecko, Stanislaw Sierakowski, Oliver Distler, Sylwia Chwiesko, Izabela Domyslawska, Steffen Gay
Characterization of immunoglobulin mutations in humans with activation-induced cytidine deaminase deficiency
Nancy S Longo, Colleen Satorius, Anne Durandy, Peter E Lipsky
CXCL13, CCL21 and CXCL12 are upregulated in mucosal-associated lymphoid tissue lymphomas in patients with Sjorgen's syndrome and cooperate in the maintenance of the immune response and malignant cell survival
F Barone, M Bombardieri, J Spencer, P Isaacson, F Humby, P Morgan, S Challacombe, G Valesini, C Pitzalis
Fine-specificity of the antibodies against citrullinated protein response is influenced by shared epitope alleles
KN Verpoort, K Cheung, A Ioan-Facsinay, AHM van der Helm-van Mil, RRP de Vries, FC Breedveld, TWJ Huizinga, GJM Pruijn, REM Toes
Activation of synovial fibroblasts by laminin-1 and transforming growth factor beta induces expression of stromelysins independently of TNFα, IL-1β or NF-κB
Katrin Warstat, Thomas Pap, Gerd Klein, Steffen Gay, Wilhelm K Aicher
Tumor necrosis factor polymorphisms in psoriatic arthritis: association with the promoter polymorphism TNF-857 independent of the PSORS1 risk allele
K Reich, U Hüffmeier, IR König, J Lascorz, J Lohmann, J Wendler, H Traupe, R Mössner, A Reis, H Burkhardt
Safety and diagnostic value of medical arthroscopy: retrospective analysis of 100 medical arthroscopies performed by a rheumatologist
Ved Chaturvedi
Investigation of the role of the p38 MAPK α and δ isoforms in nonresponse to tumour necrosis factor blockade in the synovium of rheumatoid arthritis patients
LR Coulthard, LD Church, RJ Mathews, S Churchman, L Dickie, M Buch, R Reece, A English, AW Morgan, S Gay, P Emery, MF McDermott
The synovial cadherin (cadherin-11) promotes intercellular motility
Hans P Kiener, Christopher S Stipp, Philip G Allen, David M Lee, Michael B Brenner
Cadherin-11 regulates synovial fibroblast behavior in health and disease
David M Lee, Hans P Kiener, Sandeep K Agarwal, Erika H Noss, Gerald FM Watts, Osamu Chisaka, Masatoshi Takeichi, Michael B Brenner
Toll-like receptor 9 agonists and IL-15 promote activation, proliferation, secretion of proinflammatory cytokines and differentiation of B cells isolated from bone marrow of rheumatoid arthritis patients
W Rudnicka, E Warnawin, T Burakowski, M Bik, E Kontny, M Chorazy-Massalska, A Radzikowska, M Buler, P Maldyk, W Maslinski
Class switched memory B cells are enriched in the synovium after rituximab treatment
Burkhard Möller, Istvan Vajtai, Sabine Adler, Stefan Eggli, Hans-Rudolf Ziswiler, Clemens Dahinden, Peter M Villiger
Evidence for the role of CD74 in innate immunity, arthritis, and the action of migration inhibitory factor
Eric Morand, Lanie Santos, Pamela Hall, Michael Hickey
Nitric oxide differentially regulates T-cell function in rheumatoid arthritis and systemic lupus erythematosus
Gyorgy Nagy, Joanna M Clark, Edit Buzas, Claire L Gorman, Pal Geher, Andras Perl, Andras Falus, Andrew P Cope
Circulating levels of IL-7 in rheumatoid arthritis
S Churchman, S Field, C Burgoyne, A Brown, P Emery, F Ponchel
The regulation of IL-7 production in synovial stromal cells in rheumatoid arthritis is promiscuous
S Field, E Jones, A English, C Burgoyne, S Churchman, R Reece, P Emery, F Ponchel
Mesenchymal stem cell repair capabilities are defective in rheumatoid arthritis in relation with in vivo exposure to inflammation
E Jones, S Field, A English, R Reece, P Emery, D McGonagle, F Ponchel
Diagnostic value of anticyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis: association with extra-articular manifestations
Ioannis Alexiou, Anastasios Germenis, Athanasios Ziogas, Athanasios Koutroumbas, Katerina Theodoridou, Anastasia Kontogianni, Lazaros I Sakkas
Phase 1 study of TRU-015, a CD20-directed small modular immunopharmaceutical (SMIP™) protein therapeutic, in subjects with rheumatoid arthritis
DJ Burge, SA Bookbinder, AJ Kivitz, RM Fleischmann, C Shu, J Bannink, D Barone
TRU-015, a small modular immunopharmaceutical (SMIP™) drug candidate directed against CD20, demonstrates clinical improvement in subjects with rheumatoid arthritis
DJ Burge, C Shu, RW Martin, TW Littlejohn, DJ Wallace, J Taborn, WR Palmer, A Kivitz
Quantiferon-TB Gold test in screening for latent tuberculosis before and during antitumour necrosis factor treatment
J Vencovský, M Havelková, Š Forejtová, K Jarošová, I Pùtová
Peroxisome proliferator-activated receptor gamma 1 expression is diminished in human osteoarthritis cartilage and is downregulated by IL-1β in articular chondrocytes
H Afif, L Mfuna, J Martel-Pelletier, J-P Pelletier, H Fahmi
Abnormal collagen type 1 production in subchondral osteoarthritic osteoblasts is responsible in part for altered mineralization in these cells
Denis Chouchourel, Geneviève Bariteau, Aline Delalandre, Daniel Lajeunesse
Altered expression and production of leptin is responsible for abnormal cell markers in subchondral osteoblasts from osteoarthritic patients
Daniel Lajeunesse, Marie-Solange Mutabaruka, Mohamed Aoulab-Aissa, Aline Delalandre
Molecular mechanisms involved in a differential association of Frzb biology with osteoarthritis and osteoporosis
Rik JU Lories, Jan Schrooten, Inge Derese, Jenny Peeters, Astrid Bakker, Frank P Luyten
Matrix remodeling during enchondral ossification and aggrecan cleavage in osteoarthritic cartilage depends on syndecan-4
Frank Echtermeyer, Katja Neugebauer, Ingmar Meinecke, Christine Herzog, Rita Dreier, Thomas Pap
Differential Toll-like receptor-dependent collagenase expression in chondrocytes
Qian Zhang, Wang Hui, Rose Davidson, Clare Darrah, Simon T Donell, Ian M Clark, Tim E Cawston, John H Robinson, Andrew D Rowan, David A Young