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Published in: BMC Health Services Research 1/2010

Open Access 01-12-2010 | Research article

Application of a theoretical model to evaluate COPD disease management

Authors: Karin MM Lemmens, Anna P Nieboer, Maureen PMH Rutten-Van Mölken, Constant P van Schayck, Javier D Asin, Jos AM Dirven, Robbert Huijsman

Published in: BMC Health Services Research | Issue 1/2010

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Abstract

Background

Disease management programmes are heterogeneous in nature and often lack a theoretical basis. An evaluation model has been developed in which theoretically driven inquiries link disease management interventions to outcomes. The aim of this study is to methodically evaluate the impact of a disease management programme for patients with chronic obstructive pulmonary disease (COPD) on process, intermediate and final outcomes of care in a general practice setting.

Methods

A quasi-experimental research was performed with 12-months follow-up of 189 COPD patients in primary care in the Netherlands. The programme included patient education, protocolised assessment and treatment of COPD, structural follow-up and coordination by practice nurses at 3, 6 and 12 months. Data on intermediate outcomes (knowledge, psychosocial mediators, self-efficacy and behaviour) and final outcomes (dyspnoea, quality of life, measured by the CRQ and CCQ, and patient experiences) were obtained from questionnaires and electronic registries.

Results

Implementation of the programme was associated with significant improvements in dyspnoea (p < 0.001) and patient experiences (p < 0.001). No significant improvement was found in mean quality of life scores. Improvements were found in several intermediate outcomes, including investment beliefs (p < 0.05), disease-specific knowledge (p < 0.01; p < 0.001) and medication compliance (p < 0.01). Overall, process improvement was established. The model showed associations between significantly improved intermediate outcomes and improvements in quality of life and dyspnoea.

Conclusions

The application of a theory-driven model enhances the design and evaluation of disease management programmes aimed at improving health outcomes. This study supports the notion that a theoretical approach strengthens the evaluation designs of complex interventions. Moreover, it provides prudent evidence that the implementation of COPD disease management programmes can positively influence outcomes of care.
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Literature
1.
go back to reference WHO: Preventing chronic diseases: a vital investment. 2005, Geneva: World Health Organisation WHO: Preventing chronic diseases: a vital investment. 2005, Geneva: World Health Organisation
2.
go back to reference Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ: Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet. 2006, 367 (9524): 1747-1757. 10.1016/S0140-6736(06)68770-9.CrossRefPubMed Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ: Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet. 2006, 367 (9524): 1747-1757. 10.1016/S0140-6736(06)68770-9.CrossRefPubMed
3.
go back to reference Pauwels RA, Rabe KF: Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet. 2004, 364 (9434): 613-620. 10.1016/S0140-6736(04)16855-4.CrossRefPubMed Pauwels RA, Rabe KF: Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet. 2004, 364 (9434): 613-620. 10.1016/S0140-6736(04)16855-4.CrossRefPubMed
4.
go back to reference Hoogendoorn M, Rutten-van Molken MP, Hoogenveen RT, van Genugten ML, Buist AS, Wouters EF, Feenstra TL: A dynamic population model of disease progression in COPD. Eur Respir J. 2005, 26 (2): 223-233. 10.1183/09031936.05.00122004.CrossRefPubMed Hoogendoorn M, Rutten-van Molken MP, Hoogenveen RT, van Genugten ML, Buist AS, Wouters EF, Feenstra TL: A dynamic population model of disease progression in COPD. Eur Respir J. 2005, 26 (2): 223-233. 10.1183/09031936.05.00122004.CrossRefPubMed
5.
go back to reference Epping-Jordan JE: Integrated approaches to prevention and control of chronic conditions. Kidney Int Suppl. 2005, S86-88. 10.1111/j.1523-1755.2005.09816.x. 98 Epping-Jordan JE: Integrated approaches to prevention and control of chronic conditions. Kidney Int Suppl. 2005, S86-88. 10.1111/j.1523-1755.2005.09816.x. 98
6.
go back to reference Lemmens KM, Nieboer AP, van Schayck CP, Asin JD, Huijsman R: A model to evaluate quality and effectiveness of disease management. Qual Saf Health Care. 2008, 17 (6): 447-453. 10.1136/qshc.2006.021865.CrossRefPubMed Lemmens KM, Nieboer AP, van Schayck CP, Asin JD, Huijsman R: A model to evaluate quality and effectiveness of disease management. Qual Saf Health Care. 2008, 17 (6): 447-453. 10.1136/qshc.2006.021865.CrossRefPubMed
7.
9.
go back to reference Shadish W, Cook T, Campbell D: Experimental and quasi-experimental designs for generalized causal inference. 2002, Boston - New York: Houghton Mifflin Company Shadish W, Cook T, Campbell D: Experimental and quasi-experimental designs for generalized causal inference. 2002, Boston - New York: Houghton Mifflin Company
10.
go back to reference Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, Tyrer P: Framework for design and evaluation of complex interventions to improve health. BMJ. 2000, 321 (7262): 694-696. 10.1136/bmj.321.7262.694.CrossRefPubMedPubMedCentral Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, Tyrer P: Framework for design and evaluation of complex interventions to improve health. BMJ. 2000, 321 (7262): 694-696. 10.1136/bmj.321.7262.694.CrossRefPubMedPubMedCentral
11.
go back to reference Meulepas MA, Braspenning JC, de Grauw WJ, Lucas AE, Wijkel D, Grol RP: Patient-oriented intervention in addition to centrally organised checkups improves diabetic patient outcome in primary care. Qual Saf Health Care. 2008, 17 (5): 324-328. 10.1136/qshc.2006.021204.CrossRefPubMed Meulepas MA, Braspenning JC, de Grauw WJ, Lucas AE, Wijkel D, Grol RP: Patient-oriented intervention in addition to centrally organised checkups improves diabetic patient outcome in primary care. Qual Saf Health Care. 2008, 17 (5): 324-328. 10.1136/qshc.2006.021204.CrossRefPubMed
12.
go back to reference Schellevis FG, Westert GP, de Bakker DH, Groenewegen PP: Tweede Nationale Studie naar ziekten en verrichtingen in de huisartspraktijk. Vraagstellingen en methoden. 2004, Utrecht/Bilthoven: NIVEL/RIVM Schellevis FG, Westert GP, de Bakker DH, Groenewegen PP: Tweede Nationale Studie naar ziekten en verrichtingen in de huisartspraktijk. Vraagstellingen en methoden. 2004, Utrecht/Bilthoven: NIVEL/RIVM
13.
go back to reference Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, et al: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007, 176 (6): 532-555. 10.1164/rccm.200703-456SO.CrossRefPubMed Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, et al: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007, 176 (6): 532-555. 10.1164/rccm.200703-456SO.CrossRefPubMed
14.
go back to reference Bonomi AE, Wagner EH, Glasgow RE, VonKorff M: Assessment of chronic illness care (ACIC): a practical tool to measure quality improvement. Health Serv Res. 2002, 37 (3): 791-820. 10.1111/1475-6773.00049.CrossRefPubMedPubMedCentral Bonomi AE, Wagner EH, Glasgow RE, VonKorff M: Assessment of chronic illness care (ACIC): a practical tool to measure quality improvement. Health Serv Res. 2002, 37 (3): 791-820. 10.1111/1475-6773.00049.CrossRefPubMedPubMedCentral
15.
go back to reference Deenen TAM: Patient Health-education and self-management: A medical-psychological intervention study on severe asthma and COPD in a high altitute clinic. Dissertation. Rijksuniversiteit Groningen. 1996, (an English translation is on request available from the contact author) Deenen TAM: Patient Health-education and self-management: A medical-psychological intervention study on severe asthma and COPD in a high altitute clinic. Dissertation. Rijksuniversiteit Groningen. 1996, (an English translation is on request available from the contact author)
16.
go back to reference Schuurmans H, Steverink N, Frieswijk N, Buunk BP, Slaets JP, Lindenberg S: How to measure self-management abilities in older people by self-report. The development of the SMAS-30. Qual Life Res. 2005, 14 (10): 2215-2228. 10.1007/s11136-005-8166-9.CrossRefPubMed Schuurmans H, Steverink N, Frieswijk N, Buunk BP, Slaets JP, Lindenberg S: How to measure self-management abilities in older people by self-report. The development of the SMAS-30. Qual Life Res. 2005, 14 (10): 2215-2228. 10.1007/s11136-005-8166-9.CrossRefPubMed
17.
go back to reference Steverink N, Lindenberg S, Slaets JP: How to understand and improve older people's self-management of wellbeing. European Journal of Ageing. 2005, 2: 235-244. 10.1007/s10433-005-0012-y.CrossRef Steverink N, Lindenberg S, Slaets JP: How to understand and improve older people's self-management of wellbeing. European Journal of Ageing. 2005, 2: 235-244. 10.1007/s10433-005-0012-y.CrossRef
18.
go back to reference Schunemann HJ, Puhan M, Goldstein R, Jaeschke R, Guyatt GH: Measurement properties and interpretability of the Chronic respiratory disease questionnaire (CRQ). Copd. 2005, 2 (1): 81-89. 10.1081/COPD-200050651.CrossRefPubMed Schunemann HJ, Puhan M, Goldstein R, Jaeschke R, Guyatt GH: Measurement properties and interpretability of the Chronic respiratory disease questionnaire (CRQ). Copd. 2005, 2 (1): 81-89. 10.1081/COPD-200050651.CrossRefPubMed
19.
go back to reference Williams JE, Singh SJ, Sewell L, Morgan MD: Health status measurement: sensitivity of the self-reported Chronic Respiratory Questionnaire (CRQ-SR) in pulmonary rehabilitation. Thorax. 2003, 58 (6): 515-518. 10.1136/thorax.58.6.515.CrossRefPubMedPubMedCentral Williams JE, Singh SJ, Sewell L, Morgan MD: Health status measurement: sensitivity of the self-reported Chronic Respiratory Questionnaire (CRQ-SR) in pulmonary rehabilitation. Thorax. 2003, 58 (6): 515-518. 10.1136/thorax.58.6.515.CrossRefPubMedPubMedCentral
20.
go back to reference Molen Van Der T, Willemse BW, Schokker S, Ten Hacken NH, Postma DS, Juniper EF: Development, validity and responsiveness of the Clinical COPD Questionnaire. Health Qual Life Outcomes. 2003, 1 (1): 13-10.1186/1477-7525-1-13.CrossRefPubMedPubMedCentral Molen Van Der T, Willemse BW, Schokker S, Ten Hacken NH, Postma DS, Juniper EF: Development, validity and responsiveness of the Clinical COPD Questionnaire. Health Qual Life Outcomes. 2003, 1 (1): 13-10.1186/1477-7525-1-13.CrossRefPubMedPubMedCentral
21.
go back to reference EuroQol--a new facility for the measurement of health-related quality of life. The EuroQol Group. Health Policy. 1990, 16 (3): 199-208. 10.1016/0168-8510(90)90421-9. EuroQol--a new facility for the measurement of health-related quality of life. The EuroQol Group. Health Policy. 1990, 16 (3): 199-208. 10.1016/0168-8510(90)90421-9.
22.
go back to reference Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, Wedzicha JA: Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999, 54 (7): 581-586. 10.1136/thx.54.7.581.CrossRefPubMedPubMedCentral Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, Wedzicha JA: Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999, 54 (7): 581-586. 10.1136/thx.54.7.581.CrossRefPubMedPubMedCentral
23.
go back to reference Kendrick KR, Baxi SC, Smith RM: Usefulness of the modified 0-10 Borg scale in assessing the degree of dyspnea in patients with COPD and asthma. J Emerg Nurs. 2000, 26 (3): 216-222.CrossRefPubMed Kendrick KR, Baxi SC, Smith RM: Usefulness of the modified 0-10 Borg scale in assessing the degree of dyspnea in patients with COPD and asthma. J Emerg Nurs. 2000, 26 (3): 216-222.CrossRefPubMed
24.
go back to reference van Campen C, Sixma HJ, Kerssens JJ, Peters L: Assessing noninstitutionalized asthma and COPD patients' priorities and perceptions of quality of health care: the development of the QUOTE-CNSLD instrument. J Asthma. 1997, 34 (6): 531-538. 10.3109/02770909709055397.CrossRefPubMed van Campen C, Sixma HJ, Kerssens JJ, Peters L: Assessing noninstitutionalized asthma and COPD patients' priorities and perceptions of quality of health care: the development of the QUOTE-CNSLD instrument. J Asthma. 1997, 34 (6): 531-538. 10.3109/02770909709055397.CrossRefPubMed
25.
go back to reference Smeele IJM, Van Weel C, Van Schayck CP, Molen Van der T, Thoonen B, Schermer T, Sachs APE, Muris JWM, Chavannes NH, Kolnaar BGM, et al: NHG-Standaard COPD. Huisarts Wet. 2007, 50 (8): 362-379. Smeele IJM, Van Weel C, Van Schayck CP, Molen Van der T, Thoonen B, Schermer T, Sachs APE, Muris JWM, Chavannes NH, Kolnaar BGM, et al: NHG-Standaard COPD. Huisarts Wet. 2007, 50 (8): 362-379.
26.
go back to reference Van Schayck CP, Bindels PJE, Decramer M, Dekhuijzen PNR, Kerstjens HAM, Muris JWM, Asijee GM, Spreeuwenberg C: Making COPD a treatable disease - an integrated care perspective. Respir Med. 2007, 49-56. COPD update 3 Van Schayck CP, Bindels PJE, Decramer M, Dekhuijzen PNR, Kerstjens HAM, Muris JWM, Asijee GM, Spreeuwenberg C: Making COPD a treatable disease - an integrated care perspective. Respir Med. 2007, 49-56. COPD update 3
27.
go back to reference Donohue JF: Minimal clinically important differences in COPD lung function. Copd. 2005, 2 (1): 111-124. 10.1081/COPD-200053377.CrossRefPubMed Donohue JF: Minimal clinically important differences in COPD lung function. Copd. 2005, 2 (1): 111-124. 10.1081/COPD-200053377.CrossRefPubMed
28.
go back to reference Steuten L, Vrijhoef B, Van Merode F, Wesseling GJ, Spreeuwenberg C: Evaluation of a regional disease management programme for patients with asthma or chronic obstructive pulmonary disease. Int J Qual Health Care. 2006, 18 (6): 429-436. 10.1093/intqhc/mzl052.CrossRefPubMed Steuten L, Vrijhoef B, Van Merode F, Wesseling GJ, Spreeuwenberg C: Evaluation of a regional disease management programme for patients with asthma or chronic obstructive pulmonary disease. Int J Qual Health Care. 2006, 18 (6): 429-436. 10.1093/intqhc/mzl052.CrossRefPubMed
29.
go back to reference Adams SG, Smith PK, Allan PF, Anzueto A, Pugh JA, Cornell JE: Systematic review of the chronic care model in chronic obstructive pulmonary disease prevention and management. Arch Intern Med. 2007, 167 (6): 551-561. 10.1001/archinte.167.6.551.CrossRefPubMed Adams SG, Smith PK, Allan PF, Anzueto A, Pugh JA, Cornell JE: Systematic review of the chronic care model in chronic obstructive pulmonary disease prevention and management. Arch Intern Med. 2007, 167 (6): 551-561. 10.1001/archinte.167.6.551.CrossRefPubMed
30.
go back to reference Lemmens KM, Nieboer AP, Huijsman R: A systematic review of integrated use of disease-management interventions in asthma and COPD. Respir Med. 2009, 103 (5): 670-691. 10.1016/j.rmed.2008.11.017.CrossRefPubMed Lemmens KM, Nieboer AP, Huijsman R: A systematic review of integrated use of disease-management interventions in asthma and COPD. Respir Med. 2009, 103 (5): 670-691. 10.1016/j.rmed.2008.11.017.CrossRefPubMed
31.
go back to reference Niesink A, Trappenburg JC, de Weert-van Oene GH, Lammers JW, Verheij TJ, Schrijvers AJ: Systematic review of the effects of chronic disease management on quality-of-life in people with chronic obstructive pulmonary disease. Respir Med. 2007, 101 (11): 2233-2239. 10.1016/j.rmed.2007.07.017.CrossRefPubMed Niesink A, Trappenburg JC, de Weert-van Oene GH, Lammers JW, Verheij TJ, Schrijvers AJ: Systematic review of the effects of chronic disease management on quality-of-life in people with chronic obstructive pulmonary disease. Respir Med. 2007, 101 (11): 2233-2239. 10.1016/j.rmed.2007.07.017.CrossRefPubMed
32.
go back to reference Peytremann-Bridevaux I, Staeger P, Bridevaux PO, Ghali WA, Burnand B: Effectiveness of chronic obstructive pulmonary disease-management programs: systematic review and meta-analysis. Am J Med. 2008, 121 (5): 433-443. 10.1016/j.amjmed.2008.02.009. e434CrossRefPubMed Peytremann-Bridevaux I, Staeger P, Bridevaux PO, Ghali WA, Burnand B: Effectiveness of chronic obstructive pulmonary disease-management programs: systematic review and meta-analysis. Am J Med. 2008, 121 (5): 433-443. 10.1016/j.amjmed.2008.02.009. e434CrossRefPubMed
33.
go back to reference Campbell NC, Murray E, Darbyshire J, Emery J, Farmer A, Griffiths F, Guthrie B, Lester H, Wilson P, Kinmonth AL: Designing and evaluating complex interventions to improve health care. Bmj. 2007, 334 (7591): 455-459. 10.1136/bmj.39108.379965.BE.CrossRefPubMedPubMedCentral Campbell NC, Murray E, Darbyshire J, Emery J, Farmer A, Griffiths F, Guthrie B, Lester H, Wilson P, Kinmonth AL: Designing and evaluating complex interventions to improve health care. Bmj. 2007, 334 (7591): 455-459. 10.1136/bmj.39108.379965.BE.CrossRefPubMedPubMedCentral
34.
go back to reference Mattke S, Seid M, Ma S: Evidence for the effect of disease management: is $1 billion a year a good investment?. Am J Manag Care. 2007, 13 (12): 670-676.PubMed Mattke S, Seid M, Ma S: Evidence for the effect of disease management: is $1 billion a year a good investment?. Am J Manag Care. 2007, 13 (12): 670-676.PubMed
35.
go back to reference Chavannes N, Vollenberg JJ, van Schayck CP, Wouters EF: Effects of physical activity in mild to moderate COPD: a systematic review. Br J Gen Pract. 2002, 52 (480): 574-578.PubMedPubMedCentral Chavannes N, Vollenberg JJ, van Schayck CP, Wouters EF: Effects of physical activity in mild to moderate COPD: a systematic review. Br J Gen Pract. 2002, 52 (480): 574-578.PubMedPubMedCentral
36.
go back to reference Bourbeau J: Not all self-management programs in chronic obstructive pulmonary disease have positive results: why is replication a problem?. Chron Respir Dis. 2004, 1 (1): 5-6.PubMed Bourbeau J: Not all self-management programs in chronic obstructive pulmonary disease have positive results: why is replication a problem?. Chron Respir Dis. 2004, 1 (1): 5-6.PubMed
37.
go back to reference Eccles M, Grimshaw J, Campbell M, Ramsay C: Research designs for studies evaluating the effectiveness of change and improvement strategies. Qual Saf Health Care. 2003, 12 (1): 47-52. 10.1136/qhc.12.1.47.CrossRefPubMedPubMedCentral Eccles M, Grimshaw J, Campbell M, Ramsay C: Research designs for studies evaluating the effectiveness of change and improvement strategies. Qual Saf Health Care. 2003, 12 (1): 47-52. 10.1136/qhc.12.1.47.CrossRefPubMedPubMedCentral
38.
go back to reference Glasgow RE, Magid DJ, Beck A, Ritzwoller D, Estabrooks PA: Practical clinical trials for translating research to practice: design and measurement recommendations. Med Care. 2005, 43 (6): 551-557. 10.1097/01.mlr.0000163645.41407.09.CrossRefPubMed Glasgow RE, Magid DJ, Beck A, Ritzwoller D, Estabrooks PA: Practical clinical trials for translating research to practice: design and measurement recommendations. Med Care. 2005, 43 (6): 551-557. 10.1097/01.mlr.0000163645.41407.09.CrossRefPubMed
39.
go back to reference Lemmens KM, Nieboer AP, Huijsman R: Designing patient-related interventions in COPD care: Empirical test of a theoretical model. Patient Educ Couns. 2008, 72 (2): 223-231. 10.1016/j.pec.2008.04.003.CrossRefPubMed Lemmens KM, Nieboer AP, Huijsman R: Designing patient-related interventions in COPD care: Empirical test of a theoretical model. Patient Educ Couns. 2008, 72 (2): 223-231. 10.1016/j.pec.2008.04.003.CrossRefPubMed
Metadata
Title
Application of a theoretical model to evaluate COPD disease management
Authors
Karin MM Lemmens
Anna P Nieboer
Maureen PMH Rutten-Van Mölken
Constant P van Schayck
Javier D Asin
Jos AM Dirven
Robbert Huijsman
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2010
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-10-81

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