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World Journal of Surgery

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01-07-2021 | Appendicitis | Original Scientific Report

The Worldwide Epidemiology of Acute Appendicitis: An Analysis of the Global Health Data Exchange Dataset

Authors: Dakshitha P. Wickramasinghe, Chrisjit Xavier, Dharmabandhu N. Samarasekera

Published in: World Journal of Surgery | Issue 7/2021

Abstract

Background

This study aims to describe the worldwide epidemiology and changing disease trends of acute appendicitis (AA).

Methods

Epidemiological data on the incidence of AA and deaths were collected from the Global Health Data Exchange repository from 1990 to 2019. Data were stratified by age, sex and Socio-Demographic Index (SDI).

Results

In 2019, there were an estimated 17.7 million cases (incidence 228/100,000) with over 33,400 deaths (0.43/100,000). Both the absolute number and the incidence had increased from 1990 to 2019 (+ 38.8% and + 11.4%, respectively). The number of deaths and deaths per 100,000 declined during this period (− 21.8% and − 46.2%, respectively). These trends were largely similar in all 5 SDI groups. There was a significant difference in the incidence of AA between the SDI groups, with low SDI group having the lowest and high SDI group having the highest. The high SDI group had the lowest mortality rate (Kruskall–Wallis test, p < 0.001). The peak incidence was in the 15–19-year age group. The mortality rate increased exponentially from the third decade of life.

Conclusions

The mortality rate of AA is declining worldwide, while the incidence is increasing. The peak incidence is in the 15–19-year group.

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Title: The Worldwide Epidemiology of Acute Appendicitis: An Analysis of the Global Health Data Exchange Dataset
Authors: Dakshitha P. Wickramasinghe
Chrisjit Xavier
Dharmabandhu N. Samarasekera
Publication date: 01-07-2021
Publisher: Springer International Publishing
Keywords: Appendicitis
Appendicitis
Published in: World Journal of Surgery / Issue 7/2021
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-021-06077-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The Worldwide Epidemiology of Acute Appendicitis: An Analysis of the Global Health Data Exchange Dataset

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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