Published in:
01-04-2009 | Original Article
Aperitif Effects on Gastric Emptying: A Crossover Study Using Continuous Real-Time 13C Breath Test (BreathID System)
Authors:
M. Inamori, H. Iida, H. Endo, K. Hosono, T. Akiyama, K. Yoneda, K. Fujita, T. Iwasaki, H. Takahashi, M. Yoneda, A. Goto, Y. Abe, N. Kobayashi, K. Kubota, A. Nakajima
Published in:
Digestive Diseases and Sciences
|
Issue 4/2009
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Abstract
The aim of this study was to determine whether there is a correlation between aperitif and gastric emptying. Ten healthy male volunteers participated in this randomized, two-way crossover study. Under two conditions (after drinking an aperitif versus not), the 13C breath test was performed for 4 h with a liquid meal (200 kcal/200 ml) containing 100 mg 13C acetate. We used 50 ml of umeshu as the aperitif. This is a traditional Japanese plum liqueur, and contains 7 ml alcohol (14%). In the aperitif group, T
1/2, T
lag, and T
peak were significantly delayed [T
1/2 (132: 113–174) versus (112: 92–134) (P = 0.0069); T
lag (80: 63–94) versus (55: 47–85) (P = 0.0069); and T
peak (81: 62–96) versus (54: 34–84) (P = 0.0069), (median: range, aperitif versus control, min)]. Gastric emptying was significantly delayed in the aperitif group as compared with the control group. This study revealed that even a small amount of alcohol such as an aperitif may contribute to delayed gastric emptying.