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Published in: Health Economics Review 1/2019

Open Access 01-12-2019 | Aortic Valve Replacement | Research

A comparative profitability analysis of transcatheter versus surgical aortic valve replacement in a high-volume French hospital

Authors: François Huchet, Jacques Chan-Peng, Fanny d’Acremont, Patrice Guerin, Gael Grimandi, Jean-Christian Roussel, Julien Plessis, Vincent Letocart, Thomas Senage, Thibaut Manigold

Published in: Health Economics Review | Issue 1/2019

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Abstract

Background

Current scientific guidelines have extended the indication for transcatheter aortic valve replacement (TAVR) to patients who present an intermediate risk for surgery and have been so far considered for conventional surgery. We previously demonstrated that the TAVR procedure generated profits despite elevated costs, but comparison with surgery has not been performed. The objective of this study was to assess the profitability of the TAVR procedure compared with conventional surgery in a high-volume French hospital.
Consecutive patients eligible for transfemoral TAVR or surgical aortic valve replacement (SAVR) were included retrospectively in this single-centre study between September 2014 and December 2015. The primary endpoint was the profitability of each procedure (defined as the ratio between the profit and total revenues), calculated for each patient. Secondary composite endpoints included major adverse events in the 30 days following procedure and breakdown of costs.

Results

Two hundred and thirty-eight patients were included in the TAVR group and 341 in the SAVR group. TAVR patients presented higher operative risk scores and more comorbidities. Compared with SAVR, TAVR was associated with higher profits (€2732 ± 1768 per patient vs. €2177 ± 2437 per patient, P < 0.001) but also higher costs (€27,778 ± 4961 vs. €17,813 ± 6071, P < 0.001) resulting in lower profitability (9.3 ± 5.7% vs. 11.7 ± 10.1%, P < 0.001). The price of the bioprosthesis represented 70% of the TAVR total cost.

Conclusions

TAVR performed in carefully selected patients was associated with higher profits than SAVR, but also higher costs resulting in lower profitability.
Literature
1.
go back to reference Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011;364:2187–98.CrossRef Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011;364:2187–98.CrossRef
2.
go back to reference Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374:1609–20.CrossRef Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374:1609–20.CrossRef
3.
go back to reference Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2017;38:2739–91.CrossRef Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2017;38:2739–91.CrossRef
4.
go back to reference Huchet F, d’Acremont F, Letocart V, et al. Is transcatheter aortic valve replacement a profitable procedure in a high-volume French hospital? Arch Cardiovasc Dis. 2018. Huchet F, d’Acremont F, Letocart V, et al. Is transcatheter aortic valve replacement a profitable procedure in a high-volume French hospital? Arch Cardiovasc Dis. 2018.
5.
go back to reference Vahanian A, Alfieri O, Andreotti F, et al. Guidelines on the management of valvular heart disease (version 2012): the joint task force on the management of Valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg. 2012;42:S1–44.CrossRef Vahanian A, Alfieri O, Andreotti F, et al. Guidelines on the management of valvular heart disease (version 2012): the joint task force on the management of Valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg. 2012;42:S1–44.CrossRef
6.
go back to reference Eltchaninoff H, Zajarias A, Tron C, et al. Transcatheter aortic valve implantation: technical aspects, results and indications. Arch Cardiovasc Dis. 2008;101:126–32.CrossRef Eltchaninoff H, Zajarias A, Tron C, et al. Transcatheter aortic valve implantation: technical aspects, results and indications. Arch Cardiovasc Dis. 2008;101:126–32.CrossRef
7.
go back to reference Kappetein AP, Head SJ, Généreux P, et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. J Am Coll Cardiol. 2012;60:1438–54.CrossRef Kappetein AP, Head SJ, Généreux P, et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. J Am Coll Cardiol. 2012;60:1438–54.CrossRef
8.
go back to reference Ruparelia N, Latib A, Buzzatti N, et al. Long-term outcomes after Transcatheter aortic valve implantation from a single high-volume center (the Milan experience). Am J Cardiol. 2016;117:813–9.CrossRef Ruparelia N, Latib A, Buzzatti N, et al. Long-term outcomes after Transcatheter aortic valve implantation from a single high-volume center (the Milan experience). Am J Cardiol. 2016;117:813–9.CrossRef
9.
go back to reference Levi A, Landes U, Assali AR, et al. Long-term outcomes of 560 consecutive patients treated with Transcatheter aortic valve implantation and propensity score-matched analysis of early- versus new-generation valves. Am J Cardiol. 2017;119:1821–31.CrossRef Levi A, Landes U, Assali AR, et al. Long-term outcomes of 560 consecutive patients treated with Transcatheter aortic valve implantation and propensity score-matched analysis of early- versus new-generation valves. Am J Cardiol. 2017;119:1821–31.CrossRef
10.
go back to reference Wendler O, Schymik G, Treede H, et al. SOURCE 3 registry: design and 30-day results of the European Postapproval registry of the latest generation of the SAPIEN 3 Transcatheter heart valve. Circulation. 2017;135:1123–32.CrossRef Wendler O, Schymik G, Treede H, et al. SOURCE 3 registry: design and 30-day results of the European Postapproval registry of the latest generation of the SAPIEN 3 Transcatheter heart valve. Circulation. 2017;135:1123–32.CrossRef
11.
go back to reference Wendler O, Schymik G, Treede H, et al. SOURCE 3: 1-year outcomes post-transcatheter aortic valve implantation using the latest generation of the balloon-expandable transcatheter heart valve. Eur Heart J. 2017;38:2717–26.CrossRef Wendler O, Schymik G, Treede H, et al. SOURCE 3: 1-year outcomes post-transcatheter aortic valve implantation using the latest generation of the balloon-expandable transcatheter heart valve. Eur Heart J. 2017;38:2717–26.CrossRef
12.
go back to reference Reynolds MR, Magnuson EA, Lei Y, et al. Cost-effectiveness of transcatheter aortic valve replacement compared with surgical aortic valve replacement in high-risk patients with severe aortic stenosis: results of the PARTNER (placement of aortic Transcatheter valves) trial (cohort a). J Am Coll Cardiol. 2012;60:2683–92.CrossRef Reynolds MR, Magnuson EA, Lei Y, et al. Cost-effectiveness of transcatheter aortic valve replacement compared with surgical aortic valve replacement in high-risk patients with severe aortic stenosis: results of the PARTNER (placement of aortic Transcatheter valves) trial (cohort a). J Am Coll Cardiol. 2012;60:2683–92.CrossRef
13.
go back to reference Durand E, Eltchaninoff H, Canville A, et al. Feasibility and safety of early discharge after transfemoral transcatheter aortic valve implantation with the Edwards SAPIEN-XT prosthesis. Am J Cardiol. 2015;115:1116–22.CrossRef Durand E, Eltchaninoff H, Canville A, et al. Feasibility and safety of early discharge after transfemoral transcatheter aortic valve implantation with the Edwards SAPIEN-XT prosthesis. Am J Cardiol. 2015;115:1116–22.CrossRef
14.
go back to reference Sud M, Qui F, Austin PC, et al. Short length of stay after elective Transfemoral Transcatheter aortic valve replacement is not associated with increased early or late readmission risk. J Am Heart Assoc. 2017;6. Sud M, Qui F, Austin PC, et al. Short length of stay after elective Transfemoral Transcatheter aortic valve replacement is not associated with increased early or late readmission risk. J Am Heart Assoc. 2017;6.
15.
go back to reference Tam DY, Hughes A, Fremes SE, et al. A cost-utility analysis of transcatheter versus surgical aortic valve replacement for the treatment of aortic stenosis in the population with intermediate surgical risk. J Thorac Cardiovasc Surg. 2018;155:1978–88 e1.CrossRef Tam DY, Hughes A, Fremes SE, et al. A cost-utility analysis of transcatheter versus surgical aortic valve replacement for the treatment of aortic stenosis in the population with intermediate surgical risk. J Thorac Cardiovasc Surg. 2018;155:1978–88 e1.CrossRef
16.
go back to reference Siontis GC, Juni P, Pilgrim T, et al. Predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVR: a meta-analysis. J Am Coll Cardiol. 2014;64:129–40.CrossRef Siontis GC, Juni P, Pilgrim T, et al. Predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVR: a meta-analysis. J Am Coll Cardiol. 2014;64:129–40.CrossRef
Metadata
Title
A comparative profitability analysis of transcatheter versus surgical aortic valve replacement in a high-volume French hospital
Authors
François Huchet
Jacques Chan-Peng
Fanny d’Acremont
Patrice Guerin
Gael Grimandi
Jean-Christian Roussel
Julien Plessis
Vincent Letocart
Thomas Senage
Thibaut Manigold
Publication date
01-12-2019
Publisher
Springer Berlin Heidelberg
Published in
Health Economics Review / Issue 1/2019
Electronic ISSN: 2191-1991
DOI
https://doi.org/10.1186/s13561-019-0223-0

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