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Published in: The International Journal of Cardiovascular Imaging 1/2014

01-01-2014 | Original Paper

Aortic valve area assessed with 320-detector computed tomography: comparison with transthoracic echocardiography

Authors: Linnea Hornbech Larsen, Klaus Fuglsang Kofoed, Helle Gervig Carstensen, Mads Rams Mejdahl, Mads Jønsson Andersen, Jesper Kjaergaard, Olav Wendelboe Nielsen, Lars Køber, Rasmus Møgelvang, Christian Hassager

Published in: The International Journal of Cardiovascular Imaging | Issue 1/2014

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Abstract

To evaluate the diagnostic accuracy of aortic valve area (AVA) assessment with 320-detector Computed Tomography (MDCT) compared to transthoracic echocardiography (TTE) in a population with mild to severe aortic valve stenosis. AVA was estimated in 169 patients by planimetry on MDCT images (AVAMDCT) and by the continuity equation with TTE (AVATTE). To generate a reference AVA (AVAREF) we used the stroke volume from MDCT divided by the velocity time integral from CW Doppler by TTE (according to the continuity equation: stroke volume in LVOT = stroke volume passing the aortic valve). AVAREF was used as the reference to compare both measures against, since it bypasses the assumption of LVOT being circular in the continuity equation and the potential placement error of PW Doppler in the LVOT. The mean (±SD) age of the patients was 71 (±9) years, 113 (67 %) were males. Mean AVATTE was 0.93 (±0.33) cm2, mean AVAMDCT was 0.99 (±0.36) cm2 and mean AVAREF was 1.00 (±0.39) cm2. The mean difference between AVATTE and AVAMDCT was −0.06 cm2, p = 0.001, mean difference between AVATTE and AVAREF was −0.06 cm2, p < 0.001, and mean difference between AVAMDCT and AVAREF was −0.01 cm2, p = 0.60. Calcification of the aortic valve quantified by Agatston score, significantly decreased the correlation between AVAMDCT and AVAREF, (r low Agatston = 0.90, r high Agatston = 0.57). MDCT measured AVA is slightly larger than AVA measured by TTE (0.06 cm2). The accuracy and precision errors on AVA measurements are comparable for MDCT and TTE. Valvular calcification may primarily affect the accuracy of AVAMDCT.
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Metadata
Title
Aortic valve area assessed with 320-detector computed tomography: comparison with transthoracic echocardiography
Authors
Linnea Hornbech Larsen
Klaus Fuglsang Kofoed
Helle Gervig Carstensen
Mads Rams Mejdahl
Mads Jønsson Andersen
Jesper Kjaergaard
Olav Wendelboe Nielsen
Lars Køber
Rasmus Møgelvang
Christian Hassager
Publication date
01-01-2014
Publisher
Springer Netherlands
Published in
The International Journal of Cardiovascular Imaging / Issue 1/2014
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-013-0295-6

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