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Journal of Cardiothoracic Surgery

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Open Access 01-12-2021 | Aortic Dissection | Research article

Low postoperative blood platelet count may be a risk factor for 3-year mortality in patients with acute type A aortic dissection

Authors: Guangyu Liu, Hongbai Wang, Qipeng Luo, Liang Cao, Lijing Yang, Cuntao Yu, Fuxia Yan, Su Yuan

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Abstract

Background

Mortality and complications remain high after acute type A aortic dissection (ATAAD) open surgery and are associated with coagulation dysfunction. Platelets play an important role in the process of coagulation. This study explored the relationship between postoperative platelet counts and 3-year mortality after operation in patients with ATAAD undergoing open aortic repair surgery.

Methods

Patients with ATAAD who underwent Total Arch Replacement and Frozen Elephant Trunk in Fuwai Hospital from 2011 to 2015 were selected for this study. The perioperative data were collected and sorted through the electronic clinical case system. Multivariate Logistic regression was used to analyze the risk factors for death within three years after surgery.

Results

A total of 495 patients were included in the analysis. After correction for confounding factors, decreased postoperative platelet count remained an independent factor that was associated with lower mortality (OR = 0.918, 95% CI 0.853–0.988, P = 0.023).

Conclusions

The study indicated that decreased postoperative platelet count may lead to increased 3-year mortality, in patients with ATAAD who underwent open aortic repair surgery.

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Title: Low postoperative blood platelet count may be a risk factor for 3-year mortality in patients with acute type A aortic dissection
Authors: Guangyu Liu
Hongbai Wang
Qipeng Luo
Liang Cao
Lijing Yang
Cuntao Yu
Fuxia Yan
Su Yuan
Publication date: 01-12-2021
Publisher: BioMed Central
Keyword: Aortic Dissection
Published in: Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-021-01623-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Low postoperative blood platelet count may be a risk factor for 3-year mortality in patients with acute type A aortic dissection

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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