A 64-year old lady underwent a rectal polypectomy for a postero-lateral polyp at 5 cm from the anal verge. Histology demonstrated a focus of adenocarcinoma (Haggit level 3). She went on to undergo excision of the polyp scar using Trans-Anal Minimally Invasive Surgery (TAMIS), a novel technique dubbed a hybrid between Transanal Endoscopic Microsurgery (TEM) and single port laparoscopy (Figs. 1, 2, 3–4). Mucosal resection of the scar was straightforward (Figs. 5, 6, 7–8), and the patient made an uneventful recovery. Histology demonstrated no further foci of adenocarcinoma.