Skip to main content
Top
Published in: BMC Oral Health 1/2023

Open Access 01-12-2023 | Anxiety | Research

A systematic review and network meta-analysis of virtual reality, audiovisuals and music interventions for reducing dental anxiety related to tooth extraction

Authors: Tiedan Hao, Jun Pang, Qingmei Liu, Pengfei Xin

Published in: BMC Oral Health | Issue 1/2023

Login to get access

Abstract

Background

Tooth extraction is a common procedure performed by oral and maxillofacial surgeons or dentists, often resulting in dental fear and anxiety. The use of relaxing music, audiovisuals, and virtual reality (VR) technologies has been employed to reduce dental anxiety. This network meta-analysis (NMA) aimed to assess the comparative effectiveness of relaxing music, audiovisuals, and VR in reducing dental anxiety associated with tooth extraction.

Methods

Four electronic databases were searched up to March 8, 2023, to identify randomized controlled trials (RCTs) evaluating different multimedia interventions, including the application of using relaxing music, audiovisuals, and VR technologies for dental anxiety. Studies utilizing various anxiety scales for tooth extraction were considered eligible. The pooled standard mean difference (SMD) and 95% confidence interval (CI) of anxiety scale scores were analyzed using Bayesian NMA.

Results

A total of 11 RCTs were included in this NMA. The Bayesian NMA results demonstrated that relaxing music (SMD = -0.64, 95% CI: -1.04, -0.25) and VR (SMD = -0.54, 95% CI: -1.08, -0.02) were associated with a reduction in dental anxiety, while audiovisuals (SMD = -0.34, 95% CI: -0.97, 0.33) required further consideration. Ranking probabilities indicated that relaxing music might be the most acceptable method for individuals with dental anxiety. The frequentist NMA yielded consistent rankings in a sensitivity analysis.

Conclusions

Relaxing music shows the greatest potential for reducing dental anxiety related to tooth extraction when compared to other multimedia interventions.
Appendix
Available only for authorised users
Literature
1.
go back to reference Cai H, Xi P, Zhong L, Chen J, Liang X. Efficacy of aromatherapy on dental anxiety: A systematic review of randomised and quasi-randomised controlled trials. Oral Dis. 2021;27(4):829–47.PubMed Cai H, Xi P, Zhong L, Chen J, Liang X. Efficacy of aromatherapy on dental anxiety: A systematic review of randomised and quasi-randomised controlled trials. Oral Dis. 2021;27(4):829–47.PubMed
2.
go back to reference Qin Z, Zhou C, Zhu Y, Wang Y, Cao H, Li W, Huang Z. Virtual Reality for Hypertension in Tooth Extraction: A Randomized Trial. J Dent Res. 2022;101(4):400–6.PubMed Qin Z, Zhou C, Zhu Y, Wang Y, Cao H, Li W, Huang Z. Virtual Reality for Hypertension in Tooth Extraction: A Randomized Trial. J Dent Res. 2022;101(4):400–6.PubMed
3.
go back to reference Kim JY, Park SY, Han YS, Lee H. Comparison of vital sign stability and cost effectiveness between midazolam and dexmedetomidine during third molar extraction under intravenous sedation. J Korean Assoc Oral Maxillofac Surg. 2022;48(6):348–55.PubMedPubMedCentral Kim JY, Park SY, Han YS, Lee H. Comparison of vital sign stability and cost effectiveness between midazolam and dexmedetomidine during third molar extraction under intravenous sedation. J Korean Assoc Oral Maxillofac Surg. 2022;48(6):348–55.PubMedPubMedCentral
4.
go back to reference Shafi RI, Goswami M, Rahman B, Nangia T, Nisa TU, Chawla S. Comparative Evaluation of Changes in Physiological and Psychomotor Effects in Pediatric Patients during Extraction under Different Concentrations of Nitrous Oxide-Oxygen Inhalation Sedation. Contemp Clin Dent. 2021;12(4):414–8.PubMedPubMedCentral Shafi RI, Goswami M, Rahman B, Nangia T, Nisa TU, Chawla S. Comparative Evaluation of Changes in Physiological and Psychomotor Effects in Pediatric Patients during Extraction under Different Concentrations of Nitrous Oxide-Oxygen Inhalation Sedation. Contemp Clin Dent. 2021;12(4):414–8.PubMedPubMedCentral
5.
go back to reference da Cunha RS, Amorim KS, Gercina AC, de Oliveira ACA, Dos Santos Menezes L, Groppo FC, Souza LMA. Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial. Clin Oral Investig. 2021;25(3):1579–86.PubMed da Cunha RS, Amorim KS, Gercina AC, de Oliveira ACA, Dos Santos Menezes L, Groppo FC, Souza LMA. Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial. Clin Oral Investig. 2021;25(3):1579–86.PubMed
6.
go back to reference Arslan I, Aydinoglu S, Karan NB. Can lavender oil inhalation help to overcome dental anxiety and pain in children? A randomized clinical trial. Eur J Pediatr. 2020;179(6):985–92.PubMed Arslan I, Aydinoglu S, Karan NB. Can lavender oil inhalation help to overcome dental anxiety and pain in children? A randomized clinical trial. Eur J Pediatr. 2020;179(6):985–92.PubMed
7.
go back to reference Brignardello-Petersen R. There seems to be similar control of anxiety with diazepam, midazolam, and nitrous oxide in patients undergoing surgical maxillary third-molar extraction. J Am Dent Assoc. 2020;151(1):e8.PubMed Brignardello-Petersen R. There seems to be similar control of anxiety with diazepam, midazolam, and nitrous oxide in patients undergoing surgical maxillary third-molar extraction. J Am Dent Assoc. 2020;151(1):e8.PubMed
8.
go back to reference Elicherla SR, Bandi S, Nunna M, Saikiran KV, Sahithi V, Nuvvula S. Comparative evaluation of efficacy of Physics Forceps versus conventional forceps in pediatric dental extractions: a prospective randomized study. J Dent Anesth Pain Med. 2021;21(6):547–56.PubMedPubMedCentral Elicherla SR, Bandi S, Nunna M, Saikiran KV, Sahithi V, Nuvvula S. Comparative evaluation of efficacy of Physics Forceps versus conventional forceps in pediatric dental extractions: a prospective randomized study. J Dent Anesth Pain Med. 2021;21(6):547–56.PubMedPubMedCentral
9.
go back to reference Hao Y, Zhang Z, Meng Y. Application Effect of Computer-Assisted Local Anesthesia in Patient Operation. Contrast Media Mol Imaging. 2021;2021:8643867.PubMedPubMedCentral Hao Y, Zhang Z, Meng Y. Application Effect of Computer-Assisted Local Anesthesia in Patient Operation. Contrast Media Mol Imaging. 2021;2021:8643867.PubMedPubMedCentral
10.
go back to reference Brunton PA, McLean M, Vedagiri S, McKeage J, Ruddy B, Weatherly K, White D, Taberner A, Loch C. Jet injection needle-free dental anaesthesia: Initial findings. J Dent. 2022;122:104165.PubMed Brunton PA, McLean M, Vedagiri S, McKeage J, Ruddy B, Weatherly K, White D, Taberner A, Loch C. Jet injection needle-free dental anaesthesia: Initial findings. J Dent. 2022;122:104165.PubMed
11.
go back to reference Facco E, Bacci C, Zanette G. Hypnosis as sole anesthesia for oral surgery: The egg of Columbus. J Am Dent Assoc. 2021;152(9):756–62.PubMed Facco E, Bacci C, Zanette G. Hypnosis as sole anesthesia for oral surgery: The egg of Columbus. J Am Dent Assoc. 2021;152(9):756–62.PubMed
12.
go back to reference Sabherwal P, Kalra N, Tyagi R, Khatri A, Srivastava S. Hypnosis and progressive muscle relaxation for anxiolysis and pain control during extraction procedure in 8–12-year-old children: a randomized control trial. Eur Arch Paediatr Dent. 2021;22(5):823–32.PubMedPubMedCentral Sabherwal P, Kalra N, Tyagi R, Khatri A, Srivastava S. Hypnosis and progressive muscle relaxation for anxiolysis and pain control during extraction procedure in 8–12-year-old children: a randomized control trial. Eur Arch Paediatr Dent. 2021;22(5):823–32.PubMedPubMedCentral
13.
go back to reference Mackey EF. Effects of hypnosis as an adjunct to intravenous sedation for third molar extraction: a randomized, blind, controlled study. Int J Clin Exp Hypn. 2010;58(1):21–38.PubMed Mackey EF. Effects of hypnosis as an adjunct to intravenous sedation for third molar extraction: a randomized, blind, controlled study. Int J Clin Exp Hypn. 2010;58(1):21–38.PubMed
14.
go back to reference Kunusoth R, Colvenkar S, Alwala AM, Sampreethi S, Ahmed MS. Massage Therapy to Control Anxiety Before Extraction of an Impacted Tooth. Cureus. 2022;14(10):e29893.PubMedPubMedCentral Kunusoth R, Colvenkar S, Alwala AM, Sampreethi S, Ahmed MS. Massage Therapy to Control Anxiety Before Extraction of an Impacted Tooth. Cureus. 2022;14(10):e29893.PubMedPubMedCentral
15.
go back to reference Corah NL. Development of a dental anxiety scale. J Dent Res. 1969;48(4):596.PubMed Corah NL. Development of a dental anxiety scale. J Dent Res. 1969;48(4):596.PubMed
16.
17.
go back to reference Monteiro J, da Silva Barbirato D, Moraes SLD, Pellizzer EP, do Egito Vasconcelos BC. Does listening to music reduce anxiety and pain in third molar surgery-a systematic review. Clin Oral Investig. 2022;26(10):6079–86.PubMed Monteiro J, da Silva Barbirato D, Moraes SLD, Pellizzer EP, do Egito Vasconcelos BC. Does listening to music reduce anxiety and pain in third molar surgery-a systematic review. Clin Oral Investig. 2022;26(10):6079–86.PubMed
18.
go back to reference Souza MRF, Gonçalves MWA, de Souza GM, Fernandes IA, Galvão EL, Falci SGM. Does watching an informative video reduce the anxiety in patients undergoing third molar surgery: a systematic review of randomized controlled trials. Oral Maxillofac Surg. 2022; Online ahead of print. Souza MRF, Gonçalves MWA, de Souza GM, Fernandes IA, Galvão EL, Falci SGM. Does watching an informative video reduce the anxiety in patients undergoing third molar surgery: a systematic review of randomized controlled trials. Oral Maxillofac Surg. 2022; Online ahead of print.
19.
go back to reference Murad MH, Wang Z, Chu H, Lin L. When continuous outcomes are measured using different scales: guide for meta-analysis and interpretation. BMJ. 2019;364:k4817.PubMedPubMedCentral Murad MH, Wang Z, Chu H, Lin L. When continuous outcomes are measured using different scales: guide for meta-analysis and interpretation. BMJ. 2019;364:k4817.PubMedPubMedCentral
20.
go back to reference Sterne JAC, Savovic J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.PubMed Sterne JAC, Savovic J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.PubMed
21.
go back to reference Nikolakopoulou A, Higgins JPT, Papakonstantinou T, Chaimani A, Del Giovane C, Egger M, Salanti G. CINeMA: An approach for assessing confidence in the results of a network meta-analysis. PLoS Med. 2020;17(4):e1003082.PubMedPubMedCentral Nikolakopoulou A, Higgins JPT, Papakonstantinou T, Chaimani A, Del Giovane C, Egger M, Salanti G. CINeMA: An approach for assessing confidence in the results of a network meta-analysis. PLoS Med. 2020;17(4):e1003082.PubMedPubMedCentral
22.
go back to reference Harrer M, Cuijpers P, Furukawa T, Ebert D. Doing Meta-Analysis with R: A Hands-On Guide. 1st ed. 2021. Harrer M, Cuijpers P, Furukawa T, Ebert D. Doing Meta-Analysis with R: A Hands-On Guide. 1st ed. 2021.
23.
go back to reference Du Q, Ma X, Wang S, Zhou S, Luo C, Tian K, Fei W, Liu X. A digital intervention using virtual reality helmets to reduce dental anxiety of children under local anesthesia and primary teeth extraction: A randomized clinical trial. Brain Behav. 2022;12(6):e2600.PubMedPubMedCentral Du Q, Ma X, Wang S, Zhou S, Luo C, Tian K, Fei W, Liu X. A digital intervention using virtual reality helmets to reduce dental anxiety of children under local anesthesia and primary teeth extraction: A randomized clinical trial. Brain Behav. 2022;12(6):e2600.PubMedPubMedCentral
24.
go back to reference Yamashita K, Uto A, Uchino M, Kibe T, Sugimura M. Listening to music before tooth extraction attenuates sympathetic nervous system activity: A randomized control trial. Oral Sci Int. 2023;20(2):88–94. Yamashita K, Uto A, Uchino M, Kibe T, Sugimura M. Listening to music before tooth extraction attenuates sympathetic nervous system activity: A randomized control trial. Oral Sci Int. 2023;20(2):88–94.
25.
go back to reference Menziletoglu D, Guler AY, Cayir T, Isik BK. Binaural beats or 432 Hz music? which method is more effective for reducing preoperative dental anxiety? Med Oral Patol Oral Cir Bucal. 2021;26(1):e97–101.PubMed Menziletoglu D, Guler AY, Cayir T, Isik BK. Binaural beats or 432 Hz music? which method is more effective for reducing preoperative dental anxiety? Med Oral Patol Oral Cir Bucal. 2021;26(1):e97–101.PubMed
26.
go back to reference Luque-Ribas M, Figueiredo R, Guerra-Pereira I, Valmaseda-Castellón E. Effect of audiovisual eyeglasses on intraoperative pain, anxiety, and hemodynamic changes during mandibular third molar extraction: a randomized controlled clinical trial. Quintessence Int. 2020;51(8):640–8.PubMed Luque-Ribas M, Figueiredo R, Guerra-Pereira I, Valmaseda-Castellón E. Effect of audiovisual eyeglasses on intraoperative pain, anxiety, and hemodynamic changes during mandibular third molar extraction: a randomized controlled clinical trial. Quintessence Int. 2020;51(8):640–8.PubMed
27.
go back to reference Yamashita Y, Shimohira D, Aijima R, Mori K, Danjo A. Clinical Effect of Virtual Reality to Relieve Anxiety During Impacted Mandibular Third Molar Extraction Under Local Anesthesia. J Oral Maxillofac Surg. 2020;78(4):545 e541-545 e546. Yamashita Y, Shimohira D, Aijima R, Mori K, Danjo A. Clinical Effect of Virtual Reality to Relieve Anxiety During Impacted Mandibular Third Molar Extraction Under Local Anesthesia. J Oral Maxillofac Surg. 2020;78(4):545 e541-545 e546.
28.
go back to reference Yamashita K, Kibe T, Ohno S, Kohjitani A, Sugimura M. The Effects of Music Listening During Extraction of the Impacted Mandibular Third Molar on the Autonomic Nervous System and Psychological State. J Oral Maxillofac Surg. 2019;77(6):1153.e1151-1153.e1158. Yamashita K, Kibe T, Ohno S, Kohjitani A, Sugimura M. The Effects of Music Listening During Extraction of the Impacted Mandibular Third Molar on the Autonomic Nervous System and Psychological State. J Oral Maxillofac Surg. 2019;77(6):1153.e1151-1153.e1158.
29.
go back to reference Miyata K, Odanaka H, Nitta Y, Shimoji S, Kanehira T, Kawanami M, Fujisawa T. Music before Dental Surgery Suppresses Sympathetic Activity Derived from Preoperative Anxiety: A Randomized Controlled Trial. JDR Clin Trans Res. 2016;1(2):153–62.PubMed Miyata K, Odanaka H, Nitta Y, Shimoji S, Kanehira T, Kawanami M, Fujisawa T. Music before Dental Surgery Suppresses Sympathetic Activity Derived from Preoperative Anxiety: A Randomized Controlled Trial. JDR Clin Trans Res. 2016;1(2):153–62.PubMed
30.
go back to reference Kim YK, Kim SM, Myoung H. Musical intervention reduces patients’ anxiety in surgical extraction of an impacted mandibular third molar. J Oral Maxillofac Surg. 2011;69(4):1036–45.PubMed Kim YK, Kim SM, Myoung H. Musical intervention reduces patients’ anxiety in surgical extraction of an impacted mandibular third molar. J Oral Maxillofac Surg. 2011;69(4):1036–45.PubMed
31.
go back to reference Sorribes de Ramon LA, Ferrandez Martinez AF, Garcia Carricondo AR, Espin Galvez F, Alarcon Rodriguez R. Effect of virtual reality and music therapy on anxiety and perioperative pain in surgical extraction of impacted third molars. J Am Dent Assoc. 2023;154(3):206–14.PubMed Sorribes de Ramon LA, Ferrandez Martinez AF, Garcia Carricondo AR, Espin Galvez F, Alarcon Rodriguez R. Effect of virtual reality and music therapy on anxiety and perioperative pain in surgical extraction of impacted third molars. J Am Dent Assoc. 2023;154(3):206–14.PubMed
32.
go back to reference Gs G, George S, Anandaraj S, Sain S, Jose D, Sreenivas A, Pillai G, Mol N. Comparative Evaluation of the Efficacy of Virtual Reality Distraction, Audio Distraction and Tell-show-do Techniques in Reducing the Anxiety Level of Pediatric Dental Patients: An In Vivo Study. Int J Clin Pediatr Dent. 2021;14(Suppl 2):S173–8.PubMedPubMedCentral Gs G, George S, Anandaraj S, Sain S, Jose D, Sreenivas A, Pillai G, Mol N. Comparative Evaluation of the Efficacy of Virtual Reality Distraction, Audio Distraction and Tell-show-do Techniques in Reducing the Anxiety Level of Pediatric Dental Patients: An In Vivo Study. Int J Clin Pediatr Dent. 2021;14(Suppl 2):S173–8.PubMedPubMedCentral
33.
go back to reference Prabhakar AR, Marwah N, Raju OS. A comparison between audio and audiovisual distraction techniques in managing anxious pediatric dental patients. J Indian Soc Pedod Prev Dent. 2007;25(4):177–82.PubMed Prabhakar AR, Marwah N, Raju OS. A comparison between audio and audiovisual distraction techniques in managing anxious pediatric dental patients. J Indian Soc Pedod Prev Dent. 2007;25(4):177–82.PubMed
34.
go back to reference Lu C, Zhang YY, Xiang B, Peng SM, Gu M, Wong HM. Management of fear and anxiety in dental treatments: a systematic review and meta-analysis of randomized controlled trials. Odontology. 2023;111(1):20–32.PubMed Lu C, Zhang YY, Xiang B, Peng SM, Gu M, Wong HM. Management of fear and anxiety in dental treatments: a systematic review and meta-analysis of randomized controlled trials. Odontology. 2023;111(1):20–32.PubMed
35.
go back to reference Zhang C, Qin D, Shen L, Ji P, Wang J. Does audiovisual distraction reduce dental anxiety in children under local anesthesia? A systematic review and meta-analysis. Oral Dis. 2019;25(2):416–24.PubMed Zhang C, Qin D, Shen L, Ji P, Wang J. Does audiovisual distraction reduce dental anxiety in children under local anesthesia? A systematic review and meta-analysis. Oral Dis. 2019;25(2):416–24.PubMed
36.
go back to reference Gurav KM, Kulkarni N, Shetty V, Vinay V, Borade P, Ghadge S, Bhor K. Effectiveness of Audio and Audio-Visual Distraction Aids for Management of Pain and Anxiety in Children and Adults Undergoing Dental Treatment- A Systematic Review And Meta-Analysis. J Clin Pediatr Dent. 2022;46(2):86–106.PubMed Gurav KM, Kulkarni N, Shetty V, Vinay V, Borade P, Ghadge S, Bhor K. Effectiveness of Audio and Audio-Visual Distraction Aids for Management of Pain and Anxiety in Children and Adults Undergoing Dental Treatment- A Systematic Review And Meta-Analysis. J Clin Pediatr Dent. 2022;46(2):86–106.PubMed
37.
go back to reference Astramskaite I, Poskevicius L, Juodzbalys G. Factors determining tooth extraction anxiety and fear in adult dental patients: a systematic review. Int J Oral Maxillofac Surg. 2016;45(12):1630–43.PubMed Astramskaite I, Poskevicius L, Juodzbalys G. Factors determining tooth extraction anxiety and fear in adult dental patients: a systematic review. Int J Oral Maxillofac Surg. 2016;45(12):1630–43.PubMed
38.
go back to reference Toledano-Serrabona J, Sánchez-Torres A, Camps-Font O, Figueiredo R, Gay-Escoda C, Valmaseda-Castellón E. Effect of an Informative Video on Anxiety and Hemodynamic Parameters in Patients Requiring Mandibular Third Molar Extraction: A Randomized Clinical Trial. J Oral Maxillofac Surg. 2020;78(11):1933–41.PubMed Toledano-Serrabona J, Sánchez-Torres A, Camps-Font O, Figueiredo R, Gay-Escoda C, Valmaseda-Castellón E. Effect of an Informative Video on Anxiety and Hemodynamic Parameters in Patients Requiring Mandibular Third Molar Extraction: A Randomized Clinical Trial. J Oral Maxillofac Surg. 2020;78(11):1933–41.PubMed
39.
go back to reference Bradt J, Teague A. Music interventions for dental anxiety. Oral Dis. 2018;24(3):300–6.PubMed Bradt J, Teague A. Music interventions for dental anxiety. Oral Dis. 2018;24(3):300–6.PubMed
40.
go back to reference Hoffmann B, Erwood K, Ncomanzi S, Fischer V, O’Brien D, Lee A. Management strategies for adult patients with dental anxiety in the dental clinic: a systematic review. Aust Dent J. 2022;67 Suppl 1(Suppl 1):S3–13.PubMed Hoffmann B, Erwood K, Ncomanzi S, Fischer V, O’Brien D, Lee A. Management strategies for adult patients with dental anxiety in the dental clinic: a systematic review. Aust Dent J. 2022;67 Suppl 1(Suppl 1):S3–13.PubMed
41.
go back to reference Prado IM, Carcavalli L, Abreu LG, Serra-Negra JM, Paiva SM, Martins CC. Use of distraction techniques for the management of anxiety and fear in paediatric dental practice: A systematic review of randomized controlled trials. Int J Paediatr Dent. 2019;29(5):650–68.PubMed Prado IM, Carcavalli L, Abreu LG, Serra-Negra JM, Paiva SM, Martins CC. Use of distraction techniques for the management of anxiety and fear in paediatric dental practice: A systematic review of randomized controlled trials. Int J Paediatr Dent. 2019;29(5):650–68.PubMed
42.
go back to reference Liu Y, Gu Z, Wang Y, Wu Q, Chen V, Xu X, Zhou X. Effect of audiovisual distraction on the management of dental anxiety in children: A systematic review. Int J Paediatr Dent. 2019;29(1):14–21.PubMed Liu Y, Gu Z, Wang Y, Wu Q, Chen V, Xu X, Zhou X. Effect of audiovisual distraction on the management of dental anxiety in children: A systematic review. Int J Paediatr Dent. 2019;29(1):14–21.PubMed
43.
go back to reference De Stefano R, Bruno A, Muscatello MR, Cedro C, Cervino G, Fiorillo L. Fear and anxiety managing methods during dental treatments: a systematic review of recent data. Minerva Stomatol. 2019;68(6):317–31.PubMed De Stefano R, Bruno A, Muscatello MR, Cedro C, Cervino G, Fiorillo L. Fear and anxiety managing methods during dental treatments: a systematic review of recent data. Minerva Stomatol. 2019;68(6):317–31.PubMed
44.
go back to reference Quek JS, Lai B, Yap AU, Hu S. Non-pharmacological management of dental fear and anxiety in children and adolescents: An umbrella review. Eur J Paediatr Dent. 2022;23(3):230–42.PubMed Quek JS, Lai B, Yap AU, Hu S. Non-pharmacological management of dental fear and anxiety in children and adolescents: An umbrella review. Eur J Paediatr Dent. 2022;23(3):230–42.PubMed
Metadata
Title
A systematic review and network meta-analysis of virtual reality, audiovisuals and music interventions for reducing dental anxiety related to tooth extraction
Authors
Tiedan Hao
Jun Pang
Qingmei Liu
Pengfei Xin
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-023-03407-y

Other articles of this Issue 1/2023

BMC Oral Health 1/2023 Go to the issue