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01-04-2020 | Anxiety | Original Article

Heart Rate Variability and Gastric Electrical Response to a Cold Pressor Task in Youth with Functional Dyspepsia

Authors: Francisco Miguel Vargas-Luna, María Raquel Huerta-Franco, Jennifer V. Schurman, Amanda D. Deacy, Amber Bagherian, Lisa Harvey, Craig A. Friesen

Published in: Digestive Diseases and Sciences | Issue 4/2020

Abstract

Background/Aims

While stress has been implicated in functional dyspepsia (FD), the mechanisms by which stress results in symptoms are not well defined. The aim of the current study was to assess gastric myoelectric and autonomic changes in response to a physical stressor in youth with FD.

Methods

In a group of healthy controls and pediatric FD subjects, we recorded ECG and EGG signals 30 min before and 60 min after, a cold pressor task (CPT). Gastric EGG and heart rate variability (HRV) parameters were calculated in pre- and post-CPT stages and in short intervals.

Results

The pre-CPT percent tachygastria was higher in FD subjects as compared to controls. However, CPT did not induce any EGG changes in either controls or FD subjects and the two groups did not differ from each other post-CPT. The CPT resulted in an increase in HRV and standard deviation of NN intervals in controls; there was no change in any HRV parameter in FD subjects.

Conclusions

Acute physical stress does not appear to induce gastric electrical abnormalities in youth with FD. Youth with FD appear to lack the normal flexible autonomic response to a physical stressor.

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Title: Heart Rate Variability and Gastric Electrical Response to a Cold Pressor Task in Youth with Functional Dyspepsia
Authors: Francisco Miguel Vargas-Luna
María Raquel Huerta-Franco
Jennifer V. Schurman
Amanda D. Deacy
Amber Bagherian
Lisa Harvey
Craig A. Friesen
Publication date: 01-04-2020
Publisher: Springer US
Keyword: Anxiety
Published in: Digestive Diseases and Sciences / Issue 4/2020
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-019-05848-4

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