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BMC Psychiatry

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Open Access 01-12-2024 | Anxiety or Fear-Related Disorders | Study Protocol

Perinatal anxiety disorders screening study: a study protocol

Authors: Nichole Fairbrother, Bryn Stagg, Olivia Scoten, Cora Keeney, Claudia Cargnelli

Published in: BMC Psychiatry | Issue 1/2024

Abstract

Background

The anxiety and their related disorders (AD) are the most common of all mental health conditions, and affect approximately 20% of pregnant and postpartum people. They are associated with significant distress and life interference for sufferers, as well as negative consequences for fetal and infant development. At present, little if any routine screening for prenatal AD is being conducted and data regarding the most effective tools to screen for these disorders is lacking. The majority of screening studies suffer from methodological difficulties which undermine the confidence needed to recommend measures for population distribution. The primary purpose of this research is to identify the most accurate self-report tool(s) to screen for perinatal AD.

Methods

A large, prospective cohort of pregnant people (N = 1,000) is being recruited proportionally across health service delivery regions in British Columbia (BC). The screening accuracy of a broad range of perinatal AD self-report measures are being assessed using gold standard methodology. Consenting individuals are administered online questionnaires followed by a semi-structured diagnostic interview between 16- and 36-weeks’ gestation, and again between 6 and 20 weeks postpartum. Questionnaires include all screening measures, measures of sleep and unpaid family work, and questions pertaining to demographic and reproductive history, COVID-19, gender role burden, and mental health treatment utilization. Interviews assess all current anxiety disorders, as well as obsessive–compulsive disorder, and posttraumatic stress disorder.

Discussion

This research is in response to an urgent demand for accurate perinatal AD screening tools based on high quality evidence. AD among perinatal people often go unidentified and untreated, resulting in continued suffering and life impairment. Findings from this research will inform healthcare providers, policymakers, and scientists, about the most effective approach to screening for anxiety and related disorders in pregnancy in the postpartum period.

Bell NR, Grad R, Dickinson JA, Singh H, Moore AE, Kasperavicius D, et al. Better decision making in preventive health screening. Can Fam Physician. 2017;63:521–4.PubMedPubMedCentral

Colizzi M, Lasalvia A, Ruggeri M. Prevention and early intervention in youth mental health: is it time for a multidisciplinary and trans-diagnostic model for care? Int J Ment Health Syst. 2020;14:23. https://doi.org/10.1186/s13033-020-00356-9.CrossRefPubMedPubMedCentral

Fragala MS, Shiffman D, Birse CE. Population health screenings for the prevention of chronic disease progression. Am J Manag Care. 2019;25:548–53.PubMed

Austin M-P, Highnet N, Expert Working Group. Mental Health Care in the Perinatal Period: Australian Clinical Practice Guideline 2017.

Matthey S, Valenti B, Souter K, Ross-Hamid C. Comparison of four self-report measures and a generic mood question to screen for anxiety during pregnancy in English-speaking women. J Affect Disord. 2013;148:347–51. https://doi.org/10.1016/j.jad.2012.12.022.CrossRefPubMed

Meades R, Ayers S. Anxiety measures validated in perinatal populations: a systematic review. J Affect Disord. 2011;133:1–15. https://doi.org/10.1016/j.jad.2010.10.009.CrossRefPubMed

Ayers S, Coates R, Matthey S. Identifying perinatal anxiety. identifying perinatal depression and anxiety, Wiley. 2015:93–107. https://doi.org/10.1002/9781118509722.ch6.

Wilkinson A, Anderson S, Wheeler SB. Screening for and treating postpartum depression and psychosis: A cost-effectiveness analysis. Matern Child Health J. 2017;21:903–14. https://doi.org/10.1007/s10995-016-2192-9.CrossRefPubMedPubMedCentral

Wickberg B, Tjus T, Hwang P. Using the EPDS in routine antenatal care in Sweden: a naturalistic study. J Reprod Infant Psychol. 2005;23:33–41. https://doi.org/10.1080/02646830512331330956.CrossRef

10.

Heslin M, Jin H, Trevillion K, Ling X, Nath S, Barrett B, et al. Cost-effectiveness of screening tools for identifying depression in early pregnancy: a decision tree model. BMC Health Serv Res. 2022;22:774. https://doi.org/10.1186/s12913-022-08115-x.CrossRefPubMedPubMedCentral

11.

O’Connor E, Rossom RC, Henninger M, Groom HC, Burda BU. Primary care screening for and treatment of depression in pregnant and postpartum women: evidence report and systematic review for the us preventive services task force. JAMA. 2016;315:388–406. https://doi.org/10.1001/jama.2015.18948.CrossRefPubMed

12.

Waqas A, Koukab A, Meraj H, Dua T, Chowdhary N, Fatima B, et al. Screening programs for common maternal mental health disorders among perinatal women: report of the systematic review of evidence. BMC Psychiatry. 2022;22:54. https://doi.org/10.1186/s12888-022-03694-9.CrossRefPubMedPubMedCentral

13.

DeRoche C, Hooykaas A, Ou C, Charlebois J, King K. Examining the gaps in perinatal mental health care: A qualitative study of the perceptions of perinatal service providers in Canada. Front Global Womens Health 2023;4.

14.

American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5, 5th ed. Arlington, VA: American Psychiatric Publishing, Inc.; 2013. https://doi.org/10.1176/appi.books.9780890425596.

15.

Fawcett EJ, Fairbrother N, Cox ML, White IR, Fawcett JM. The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis. J Clin Psychiatry 2019;80. https://doi.org/10.4088/JCP.18r12527.

16.

Matthey S. Anxiety and Stress During Pregnancy and the Postpartum Period. In: Wenzel A, editor. The Oxford Handbook of Perinatal Psychology, Oxford University Press; 2016, p. 132–49. https://doi.org/10.1093/oxfordhb/9780199778072.013.25.

17.

Grigoriadis S, Graves L, Peer M, Mamisashvili L, Tomlinson G, Vigod SN, et al. A systematic review and meta-analysis of the effects of antenatal anxiety on postpartum outcomes. Arch Womens Ment Health. 2019;22:543–56. https://doi.org/10.1007/s00737-018-0930-2.CrossRefPubMed

18.

Ding X-X, Wu Y-L, Xu S-J, Zhu R-P, Jia X-M, Zhang S-F, et al. Maternal anxiety during pregnancy and adverse birth outcomes: a systematic review and meta-analysis of prospective cohort studies. J Affect Disord. 2014;159:103–10. https://doi.org/10.1016/j.jad.2014.02.027.CrossRefPubMed

19.

Mulder EJH, Robles de Medina PG, Huizink AC, Van den Bergh BRH, Buitelaar JK, Visser GHA. Prenatal maternal stress: effects on pregnancy and the (unborn) child. Early Hum Dev 2002;70:3–14. https://doi.org/10.1016/s0378-3782(02)00075-0.

20.

Schneider ML, Moore CF, Kraemer GW, Roberts AD, DeJesus OT. The impact of prenatal stress, fetal alcohol exposure, or both on development: perspectives from a primate model. Psychoneuroendocrinology. 2002;27:285–98. https://doi.org/10.1016/s0306-4530(01)00050-6.CrossRefPubMed

21.

Wadhwa PD, Glynn L, Hobel CJ, Garite TJ, Porto M, Chicz-DeMet A, et al. Behavioral perinatology: biobehavioral processes in human fetal development. Regul Pept. 2002;108:149–57. https://doi.org/10.1016/s0167-0115(02)00102-7.CrossRefPubMed

22.

O’Connor TG, Heron J, Glover V, Alspac Study Team. Antenatal anxiety predicts child behavioral/emotional problems independently of postnatal depression. J Am Acad Child Adolesc Psychiatry 2002;41:1470–7. https://doi.org/10.1097/00004583-200212000-00019.

23.

Korja R, Nolvi S, Grant KA, McMahon C. The relations between maternal prenatal anxiety or stress and child’s early negative reactivity or self-regulation: a systematic review. Child Psychiatry Hum Dev. 2017;48:851–69. https://doi.org/10.1007/s10578-017-0709-0.CrossRefPubMed

24.

O’Connor TG, Heron J, Golding J, Glover V, ALSPAC Study Team. Maternal antenatal anxiety and behavioural/emotional problems in children: a test of a programming hypothesis. J Child Psychol Psychiatry 2003;44:1025–36. https://doi.org/10.1111/1469-7610.00187.

25.

Erickson NL, Gartstein MA, Dotson JAW. Review of prenatal maternal mental health and the development of infant temperament. J Obstet Gynecol Neonatal Nurs. 2017;46:588–600. https://doi.org/10.1016/j.jogn.2017.03.008.CrossRefPubMed

26.

Adamson B, Letourneau N, Lebel C. Prenatal maternal anxiety and children’s brain structure and function: A systematic review of neuroimaging studies. J Affect Disord. 2018;241:117–26. https://doi.org/10.1016/j.jad.2018.08.029.CrossRefPubMed

27.

Van den Bergh BRH, Marcoen A. High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8- and 9-year-olds. Child Dev. 2004;75:1085–97. https://doi.org/10.1111/j.1467-8624.2004.00727.x.CrossRefPubMed

28.

Rees S, Channon S, Waters CS. The impact of maternal prenatal and postnatal anxiety on children’s emotional problems: a systematic review. Eur Child Adolesc Psychiatry. 2019;28:257–80. https://doi.org/10.1007/s00787-018-1173-5.CrossRefPubMed

29.

Sutter-Dallay AL, Giaconne-Marcesche V, Glatigny-Dallay E, Verdoux H. Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: a prospective survey of the MATQUID cohort. Eur Psychiatry. 2004;19:459–63. https://doi.org/10.1016/j.eurpsy.2004.09.025.CrossRefPubMed

30.

Robertson E, Grace S, Wallington T, Stewart DE. Antenatal risk factors for postpartum depression: a synthesis of recent literature. Gen Hosp Psychiatry. 2004;26:289–95. https://doi.org/10.1016/j.genhosppsych.2004.02.006.CrossRefPubMed

31.

Matthey S, Barnett B, Howie P, Kavanagh DJ. Diagnosing postpartum depression in mothers and fathers: whatever happened to anxiety? J Affect Disord. 2003;74:139–47. https://doi.org/10.1016/s0165-0327(02)00012-5.CrossRefPubMed

32.

Greenberg PE, Sisitsky T, Kessler RC, Finkelstein SN, Berndt ER, Davidson JR, et al. The economic burden of anxiety disorders in the 1990s. J Clin Psychiatry. 1999;60:427–35. https://doi.org/10.4088/jcp.v60n0702.CrossRefPubMed

33.

John-Baptiste AA, Li L, Isaranuwatchai W, Osuch E, Anderson KK. Healthcare utilization costs of emerging adults with mood and anxiety disorders in an early intervention treatment program compared to a matched cohort. Early Interv Psychiatry. 2019;13:1439–46. https://doi.org/10.1111/eip.12790.CrossRefPubMed

34.

Twomey C, Cieza A, Baldwin DS. Utility of functioning in predicting costs of care for patients with mood and anxiety disorders: a prospective cohort study. Int Clin Psychopharmacol. 2017;32:205–12. https://doi.org/10.1097/YIC.0000000000000178.CrossRefPubMedPubMedCentral

35.

Leon AC, Portera L, Weissman MM. The social costs of anxiety disorders. Br J Psychiatry Suppl 1995:19–22.

36.

Demers M. Frequent users of ambulatory health care in Quebec: the case of doctor-shoppers. CMAJ. 1995;153:37–42.PubMedPubMedCentral

37.

Fournier L, Lesage AD, Toupin J, Cyr M. Telephone surveys as an alternative for estimating prevalence of mental disorders and service utilization: a Montreal catchment area study. Can J Psychiatry. 1997;42:737–43. https://doi.org/10.1177/070674379704200706.CrossRefPubMed

38.

McCusker J, Boulenger JP, Boyer R, Bellavance F, Miller JM. Use of health services for anxiety disorders: a multisite study in Quebec. Can J Psychiatry. 1997;42:730–6. https://doi.org/10.1177/070674379704200705.CrossRefPubMed

39.

Ohayon MM, Shapiro CM, Kennedy SH. Differentiating DSM-IV anxiety and depressive disorders in the general population: comorbidity and treatment consequences. Can J Psychiatry. 2000;45:166–72. https://doi.org/10.1177/070674370004500207.CrossRefPubMed

40.

Shrestha SD, Pradhan R, Tran TD, Gualano RC, Fisher JRW. Reliability and validity of the Edinburgh Postnatal Depression Scale (EPDS) for detecting perinatal common mental disorders (PCMDs) among women in low-and lower-middle-income countries: a systematic review. BMC Pregnancy Childbirth. 2016;16:72. https://doi.org/10.1186/s12884-016-0859-2.CrossRefPubMedPubMedCentral

41.

El-Den S, Pham L, Anderson I, Yang S, Moles RJ, O’Reilly CL, et al. Perinatal depression screening: a systematic review of recommendations from member countries of the Organisation for Economic Co-operation and Development (OECD). Arch Womens Ment Health. 2022;25:871–93. https://doi.org/10.1007/s00737-022-01249-1.CrossRefPubMedPubMedCentral

42.

Dadi AF, Miller ER, Bisetegn TA, Mwanri L. Global burden of antenatal depression and its association with adverse birth outcomes: an umbrella review. BMC Public Health. 2020;20:173. https://doi.org/10.1186/s12889-020-8293-9.CrossRefPubMedPubMedCentral

43.

Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry 1987;150:782–6. https://doi.org/10.1192/bjp.150.6.782.

44.

O’Connor EA, Perdue LA, Coppola EL, Henninger ML, Thomas RG, Gaynes BN. Depression and suicide risk screening: updated evidence report and systematic review for the US preventive services task force. JAMA. 2023;329:2068–85. https://doi.org/10.1001/jama.2023.7787.CrossRefPubMed

45.

Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T. Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol. 2005;106:1071–83. https://doi.org/10.1097/01.AOG.0000183597.31630.db.CrossRefPubMed

46.

Fairbrother N, Corbyn B, Thordarson DS, Ma A, Surm D. Screening for perinatal anxiety disorders: Room to grow. J Affect Disord. 2019;250:363–70. https://doi.org/10.1016/j.jad.2019.03.052.CrossRefPubMed

47.

Accortt EE, Wong MS. It is time for routine screening for perinatal mood and anxiety disorders in obstetrics and gynecology settings. Obstet Gynecol Surv. 2017;72:553–68. https://doi.org/10.1097/OGX.0000000000000477.CrossRefPubMed

48.

Norris S, Wade R. Psychosocial assessment and screening for depression or anxiety in the perinatal period. Report (Part B). Commissioned by the Centre of Perinatal Excellence on behalf of the Australian Commonwealth Government; 2017.

49.

Kingston DE, Biringer A, McDonald SW, Heaman MI, Lasiuk GC, Hegadoren KM, et al. Preferences for mental health screening among pregnant women: a cross-sectional study. Am J Prev Med. 2015;49:e35-43. https://doi.org/10.1016/j.amepre.2015.03.026.CrossRefPubMed

50.

Hart K, Flynn H. Screening, assessment, and diagnosis of mood and anxiety disorders during pregnancy and the postpartum period. In: Wenzel A, editor. The Oxford handbook of perinatal psychology, Oxford ; New York: Oxford University Press; 2016.

51.

Eddy KT, Dutra L, Bradley R, Westen D. A multidimensional meta-analysis of psychotherapy and pharmacotherapy for obsessive-compulsive disorder. Clin Psychol Rev. 2004;24:1011–30. https://doi.org/10.1016/j.cpr.2004.08.004.CrossRefPubMed

52.

Mitte K. A meta-analysis of the efficacy of psycho- and pharmacotherapy in panic disorder with and without agoraphobia. J Affect Disord. 2005;88:27–45. https://doi.org/10.1016/j.jad.2005.05.003.ADSCrossRefPubMed

53.

Mitte K. Meta-analysis of cognitive-behavioral treatments for generalized anxiety disorder: a comparison with pharmacotherapy. Psychol Bull. 2005;131:785–95. https://doi.org/10.1037/0033-2909.131.5.785.CrossRefPubMed

54.

Marchesi C, Ossola P, Amerio A, Daniel BD, Tonna M, De Panfilis C. Clinical management of perinatal anxiety disorders: A systematic review. J Affect Disord. 2016;190:543–50. https://doi.org/10.1016/j.jad.2015.11.004.CrossRefPubMed

55.

Hadjistavropoulos H, Alberts N, Nugent M, Marchildon G. Improving Access to Psychological Services Through Therapist-Assisted. Int Deliver Cogn Behav Ther Can Psychol. 2014;55:303–11. https://doi.org/10.1037/a0037716.CrossRef

56.

Beck A, Nadkarni A, Calam R, Naeem F, Husain N. Increasing access to cognitive behaviour therapy in low and middle income Countries: A strategic framework. Asian J Psychiatr. 2016;22:190–5. https://doi.org/10.1016/j.ajp.2015.10.008.CrossRefPubMed

57.

Naeem F, Pikard J, Rao S, Ayub M, Munshi T. Is it possible to provide low-intensity cognitive behavioral treatment (CBT Lite) in Canada without additional costs to the health system? First-year evaluation of a pilot CBT Lite program. Int J Ment Health. 2017. https://doi.org/10.1080/00207411.2017.1345039.CrossRef

58.

Lindefors N, Andersson G. Guided Internet-Based Treatments in Psychiatry. 2016. https://doi.org/10.1007/978-3-319-06083-5.

59.

Wootton BM, Karin E, Dear BF, Staples L, Nielssen O, Kayrouz R, et al. Internet-delivered cognitive-behaviour therapy (ICBT) for obsessive-compulsive disorder when delivered as routine clinical care: A phase IV clinical trial. J Anxiety Disord. 2021;82: 102444. https://doi.org/10.1016/j.janxdis.2021.102444.CrossRefPubMed

60.

Arnberg FK, Linton SJ, Hultcrantz M, Heintz E, Jonsson U. Internet-delivered psychological treatments for mood and anxiety disorders: a systematic review of their efficacy, safety, and cost-effectiveness. PLoS ONE. 2014;9: e98118. https://doi.org/10.1371/journal.pone.0098118.ADSCrossRefPubMedPubMedCentral

61.

Ashford MT, Olander EK, Ayers S. Computer- or web-based interventions for perinatal mental health: A systematic review. J Affect Disord. 2016;197:134–46. https://doi.org/10.1016/j.jad.2016.02.057.CrossRefPubMed

62.

Perinatal Services BC Guidelines and Standards: Best practice guidelines for mental health disorders in the perinatal period n.d. http://www.perinatalservicesbc.ca/health-professionals/guidelines-standards Accessed 29 Aug 2023.

63.

Implementing Perinatal Mental Health Screening n.d. https://www.acog.org/programs/perinatal-mental-health/implementing-perinatal-mental-health-screening Accessed 21 Dec 2023.

64.

MGH Centre for Women’s Health. Initiative to screen all women for anxiety, including pregnant and postpartum women. MGH Center for Women’s Mental Health 2019. https://womensmentalhealth.org/posts/initiative-to-screen-all-women-for-anxiety-including-pregnant-and-postpartum-women/ Accessed 3 May 2023.

65.

Whiting PF, Rutjes AWS, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155:529–36. https://doi.org/10.7326/0003-4819-155-8-201110180-00009.CrossRefPubMed

66.

Cochrane Screening and Diagnostic Tests Methods Group. Cochrane screening and diagnostic tests 2020. https://methods.cochrane.org/sdt/ Accessed 3 May 2023.

67.

QUADAS-2. University of Bristol n.d. https://www.bristol.ac.uk/population-health-sciences/projects/quadas/quadas-2/ Accessed 30 Aug 2023.

68.

Cohen JF, Korevaar DA, Altman DG, Bruns DE, Gatsonis CA, Hooft L, et al. STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration. BMJ Open. 2016;6: e012799. https://doi.org/10.1136/bmjopen-2016-012799.CrossRefPubMedPubMedCentral

69.

Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, et al. STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ. 2015;351: h5527. https://doi.org/10.1136/bmj.h5527.CrossRefPubMedPubMedCentral

70.

Zimmerman M, Posternak MA, Chelminski I, Solomon DA. Using questionnaires to screen for psychiatric disorders: a comment on a study of screening for bipolar disorder in the community. J Clin Psychiatry 2004;65:605–10; discussion 721. https://doi.org/10.4088/jcp.v65n0503.

71.

Mandrekar JN. Receiver operating characteristic curve in diagnostic test assessment. J Thorac Oncol. 2010;5:1315–6. https://doi.org/10.1097/JTO.0b013e3181ec173d.CrossRefPubMed

72.

Sackett DL, Straus SE, Richardson WS, Rosenberg W, Haynes RB. Evidence-based medicine: how to practice and teach EBM. 2nd ed. Edinburgh; New York: Churchill Livingstone; 2000.

73.

Evans K, Spiby H, Morrell CJ. A psychometric systematic review of self-report instruments to identify anxiety in pregnancy. J Adv Nurs. 2015;71:1986–2001. https://doi.org/10.1111/jan.12649.CrossRefPubMed

74.

Overview | Antenatal and postnatal mental health: clinical management and service guidance | Guidance | NICE 2014. https://www.nice.org.uk/guidance/cg192 Accessed 28 Aug 2023.

75.

Grigoriadis S, de Camps MD, Barrons E, Bradley L, Eady A, Fishell A, et al. Mood and anxiety disorders in a sample of Canadian perinatal women referred for psychiatric care. Arch Womens Ment Health. 2011;14:325–33. https://doi.org/10.1007/s00737-011-0223-5.CrossRefPubMed

76.

Nath S, Ryan EG, Trevillion K, Bick D, Demilew J, Milgrom J, et al. Prevalence and identification of anxiety disorders in pregnancy: the diagnostic accuracy of the two-item Generalised Anxiety Disorder scale (GAD-2). BMJ Open. 2018;8: e023766. https://doi.org/10.1136/bmjopen-2018-023766.CrossRefPubMedPubMedCentral

77.

Simpson W, Glazer M, Michalski N, Steiner M, Frey BN. Comparative efficacy of the generalized anxiety disorder 7-item scale and the Edinburgh Postnatal Depression Scale as screening tools for generalized anxiety disorder in pregnancy and the postpartum period. Can J Psychiatry. 2014;59:434–40. https://doi.org/10.1177/070674371405900806.CrossRefPubMedPubMedCentral

78.

Pierson ME, Prenoveau JM, Craske MG, Netsi E, Stein A. Psychometric properties of the Generalized Anxiety Disorder Questionnaire - IV (GAD-Q-IV) in postpartum mothers. Psychol Assess. 2017;29:1391–9. https://doi.org/10.1037/pas0000443.CrossRefPubMedPubMedCentral

79.

Grant K-A, McMahon C, Austin M-P. Maternal anxiety during the transition to parenthood: a prospective study. J Affect Disord. 2008;108:101–11. https://doi.org/10.1016/j.jad.2007.10.002.CrossRefPubMed

80.

van Heyningen T, Honikman S, Tomlinson M, Field S, Myer L. Comparison of mental health screening tools for detecting antenatal depression and anxiety disorders in South African women. PLoS ONE. 2018;13: e0193697. https://doi.org/10.1371/journal.pone.0193697.CrossRefPubMedPubMedCentral

81.

Spies G, Stein DJ, Roos A, Faure SC, Mostert J, Seedat S, et al. Validity of the Kessler 10 (K-10) in detecting DSM-IV defined mood and anxiety disorders among pregnant women. Arch Womens Ment Health. 2009;12:69–74. https://doi.org/10.1007/s00737-009-0050-0.CrossRefPubMed

82.

Marley JV, Kotz J, Engelke C, Williams M, Stephen D, Coutinho S, et al. Validity and acceptability of kimberley mum’s mood scale to screen for perinatal anxiety and depression in remote aboriginal health care settings. PLoS ONE. 2017;12: e0168969. https://doi.org/10.1371/journal.pone.0168969.CrossRefPubMedPubMedCentral

83.

Yazıcı E, Mutu Pek T, Uslu Yuvacı H, Köse E, Cevrioglu S, Yazıcı AB, et al. Perinatal Anxiety Screening Scale validiy and reliability study in Turkish (PASS-TR validity and reliability). Psychiatry Clin Psychopharmacol. 2019;29:609–17. https://doi.org/10.1080/24750573.2018.1506247.CrossRef

84.

van Heyningen T, Myer L, Onah M, Tomlinson M, Field S, Honikman S. Antenatal depression and adversity in urban South Africa. J Affect Disord. 2016;203:121–9. https://doi.org/10.1016/j.jad.2016.05.052.CrossRefPubMedPubMedCentral

85.

Matthey S, Souter K, Valenti B, Ross-Hamid C. Validation of the MGMQ in screening for emotional difficulties in women during pregnancy. J Affect Disord. 2019;256:156–63. https://doi.org/10.1016/j.jad.2019.05.037.CrossRefPubMed

86.

Number of Births by Facility 2015/2016 2017.

87.

Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)–a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42:377–81. https://doi.org/10.1016/j.jbi.2008.08.010.CrossRefPubMed

88.

Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, et al. The REDCap consortium: Building an international community of software platform partners. J Biomed Inform. 2019;95: 103208. https://doi.org/10.1016/j.jbi.2019.103208.CrossRefPubMedPubMedCentral

89.

Video Conferencing, Web Conferencing, Webinars, Screen Sharing. Zoom Video n.d. https://zoom.us/ Accessed 30 Aug 2023.

90.

McCabe RE, Milosevic I, Rowa K, Shnaider P, Pawluk EJ, Antony MM, et al. Diagnostic Assessment Research Tool (DART) 2017.

91.

Schneider LH, Pawluk EJ, Milosevic I, Shnaider P, Rowa K, Antony MM, et al. The diagnostic assessment research tool in action: a preliminary evaluation of a semistructured diagnostic interview for DSM-5 disorders. Psychol Assess. 2022;34:21–9. https://doi.org/10.1037/pas0001059.CrossRefPubMed

92.

Oei TP, Evans L, Crook GM. Utility and validity of the STAI with anxiety disorder patients. Br J Clin Psychol. 1990;29:429–32. https://doi.org/10.1111/j.2044-8260.1990.tb00906.x.CrossRefPubMed

93.

Bina R, Harrington D. The Edinburgh postnatal depression scale: screening tool for postpartum anxiety as well? findings from a confirmatory factor analysis of the hebrew version. Matern Child Health J. 2016;20:904–14. https://doi.org/10.1007/s10995-015-1879-7.CrossRefPubMed

94.

Kroenke K, Spitzer RL, Williams JBW, Monahan PO, Löwe B. Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med. 2007;146:317–25. https://doi.org/10.7326/0003-4819-146-5-200703060-00004.CrossRefPubMed

95.

Kessler RC, Andrews G, Colpe LJ, Hiripi E, Mroczek DK, Normand SLT, et al. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med. 2002;32:959–76. https://doi.org/10.1017/s0033291702006074.CrossRefPubMed

96.

Somerville S, Dedman K, Hagan R, Oxnam E, Wettinger M, Byrne S, et al. The perinatal anxiety screening scale: development and preliminary validation. Arch Womens Ment Health. 2014;17:443–54. https://doi.org/10.1007/s00737-014-0425-8.CrossRefPubMed

97.

Austin M-P, Colton J, Priest S, Reilly N, Hadzi-Pavlovic D. The antenatal risk questionnaire (ANRQ): acceptability and use for psychosocial risk assessment in the maternity setting. Women Birth. 2013;26:17–25. https://doi.org/10.1016/j.wombi.2011.06.002.CrossRefPubMed

98.

Austin M-PV, Mule V, Hadzi-Pavlovic D, Reilly N. Screening for anxiety disorders in third trimester pregnancy: a comparison of four brief measures. Arch Womens Ment Health 2022;25:389–97. https://doi.org/10.1007/s00737-021-01166-9.

99.

Hahn D, Reuter K, Härter M. Screening for affective and anxiety disorders in medical patients - comparison of HADS, GHQ-12 and Brief-PHQ. Psychosoc Med 2006;3:Doc09.

100.

Huizink AC, Robles de Medina PG, Mulder EJH, Visser GHA, Buitelaar JK. Stress during pregnancy is associated with developmental outcome in infancy. J Child Psychol Psychiatry 2003;44:810–8. https://doi.org/10.1111/1469-7610.00166.

101.

Whooley MA, Avins AL, Miranda J, Browner WS. Case-finding instruments for depression. Two questions are as good as many. J Gen Intern Med 1997;12:439–45. https://doi.org/10.1046/j.1525-1497.1997.00076.x.

102.

Spielberger C, Gorsuch R, Lushene R, Vagg P, Jacobs G. Manual for the State-Trait Anxiety Inventory (Form Y1 – Y2). vol. IV. 1983.

103.

Kozinszky Z, Dudas RB. Validation studies of the Edinburgh Postnatal Depression Scale for the antenatal period. J Affect Disord. 2015;176:95–105. https://doi.org/10.1016/j.jad.2015.01.044.CrossRefPubMed

104.

Gibson J, McKenzie-McHarg K, Shakespeare J, Price J, Gray R. A systematic review of studies validating the Edinburgh Postnatal Depression Scale in antepartum and postpartum women. Acta Psychiatr Scand. 2009;119:350–64. https://doi.org/10.1111/j.1600-0447.2009.01363.x.CrossRefPubMed

105.

Bergink V, Kooistra L, Lambregtse-van den Berg MP, Wijnen H, Bunevicius R, van Baar A, et al. Validation of the Edinburgh Depression Scale during pregnancy. J Psychosomatic Res 2011;70:385–9. https://doi.org/10.1016/j.jpsychores.2010.07.008.

106.

Jomeen J, Martin CR. Confirmation of an occluded anxiety component within the Edinburgh Postnatal Depression Scale (EPDS) during early pregnancy. J Reprod Infant Psychol. 2005;23:143–54. https://doi.org/10.1080/02646830500129297.CrossRef

107.

Phillips J, Charles M, Sharpe L, Matthey S. Validation of the subscales of the Edinburgh Postnatal Depression Scale in a sample of women with unsettled infants. J Affect Disord. 2009;118:101–12. https://doi.org/10.1016/j.jad.2009.02.004.CrossRefPubMed

108.

Matthey S. Using the Edinburgh Postnatal Depression Scale to screen for anxiety disorders. Depress Anxiety. 2008;25:926–31. https://doi.org/10.1002/da.20415.CrossRefPubMed

109.

Marsay C, Manderson L, Subramaney U. Validation of the Whooley questions for antenatal depression and anxiety among low-income women in urban South Africa. S Afr J Psychiatr. 2017;23:1013. https://doi.org/10.4102/sajpsychiatry.v23i0.1013.CrossRefPubMedPubMedCentral

110.

Spitzer RL, Kroenke K, Williams JBW, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166:1092–7. https://doi.org/10.1001/archinte.166.10.1092.CrossRefPubMed

111.

Kertz S, Bigda-Peyton J, Bjorgvinsson T. Validity of the Generalized Anxiety Disorder-7 scale in an acute psychiatric sample. Clin Psychol Psychother. 2013;20:456–64. https://doi.org/10.1002/cpp.1802.CrossRefPubMed

112.

Cornelius BL, Groothoff JW, van der Klink JJ, Brouwer S. The performance of the K10, K6 and GHQ-12 to screen for present state DSM-IV disorders among disability claimants. BMC Public Health. 2013;13:128. https://doi.org/10.1186/1471-2458-13-128.CrossRefPubMedPubMedCentral

113.

Kessler RC, Barker PR, Colpe LJ, Epstein JF, Gfroerer JC, Hiripi E, et al. Screening for serious mental illness in the general population. Arch Gen Psychiatry. 2003;60:184–9. https://doi.org/10.1001/archpsyc.60.2.184.CrossRefPubMed

114.

Matthey S . [Personal Interview, Sept 2020] (Unpublished).

115.

Ruyak SL, Qeadan F. Use of the antenatal risk questionnaire to assess psychosocial risk factors associated with risk for postpartum depression: a pilot study. J Midwifery Womens Health. 2018. https://doi.org/10.1111/jmwh.12873.CrossRefPubMedPubMedCentral

116.

Fairbrother N, Stagg B, Thordarson D. Anxiety Disorder - 22 2022.(Unpublished measure)

117.

Fairbrother N, Stagg B, Thordarson D, Collardeau F. Perinatal Anxiety Screening Questionnaire 2023. (Unpublished measure)

118.

Bastien CH, Vallières A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med. 2001;2:297–307. https://doi.org/10.1016/s1389-9457(00)00065-4.CrossRefPubMed

119.

Morin CM, Belleville G, Bélanger L, Ivers H. The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep. 2011;34:601–8. https://doi.org/10.1093/sleep/34.5.601.CrossRefPubMedPubMedCentral

120.

Janzen B, Hellsten L-AM. Does the psychosocial quality of unpaid family work contribute to educational disparities in mental health among employed partnered mothers? Int Arch Occup Environ Health 2018;91:633–41. https://doi.org/10.1007/s00420-018-1310-y.

121.

Fairbrother N, Collardeau F, Albert AYK, Challacombe FL, Thordarson DS, Woody SR, et al. High prevalence and incidence of obsessive-compulsive disorder among women across pregnancy and the postpartum. J Clin Psychiatry. 2021;82:30368. https://doi.org/10.4088/JCP.20m13398.CrossRef

122.

Fairbrother N, Collardeau F, Woody SR, Wolfe DA, Fawcett JM. Postpartum thoughts of infant-related harm and obsessive-compulsive disorder: Relation to maternal physical aggression toward the infant. J Clin Psychiatry. 2022;83:39944.CrossRef

123.

Sun X, Xu W. Fast implementation of delong’s algorithm for comparing the areas under correlated receiver operating characteristic curves. IEEE Signal Process Lett. 2014;21:1389–93. https://doi.org/10.1109/LSP.2014.2337313.ADSCrossRef

124.

Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc: Ser B (Methodol). 1995;57:289–300.MathSciNet

125.

R Core Team. R: A language and environment for statistical computing 2021.

126.

IBM Corp. IBM SPSS statistics for windows, Version 25.0 2017.

Title: Perinatal anxiety disorders screening study: a study protocol
Authors: Nichole Fairbrother
Bryn Stagg
Olivia Scoten
Cora Keeney
Claudia Cargnelli
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Anxiety or Fear-Related Disorders
Anxiety
Obsessive-Compulsive Disorder
Published in: BMC Psychiatry / Issue 1/2024
Electronic ISSN: 1471-244X
DOI: https://doi.org/10.1186/s12888-024-05575-9

2024 ASCO Annual Meeting

Springer Medicine

Perinatal anxiety disorders screening study: a study protocol

Abstract

Background

Methods

Discussion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Methods

Discussion

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