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Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Antiretroviral treatment coverage in a rural district in Tanzania – a modeling study using empirical data

Authors: Francis Levira, Abela Mpobela Agnarson, Honorati Masanja, Basia Zaba, Anna Mia Ekström, Anna Thorson

Published in: BMC Public Health | Issue 1/2015

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Abstract

Background

The Tanzanian Government started scaling up its antiretroviral treatment (ART) program from referral, regional and district hospitals to primary health care facilities in October 2004. In 2010, most ART clinics were decentralized to primary health facilities. ART coverage, i.e. people living with HIV (PLHIV) on combination treatment as a proportion of those in need of treatment, provides the basis for evaluating the efficiency of ART programs at national and district level. We aimed to evaluate adult ART and pre-ART care coverage by age and sex at CD4 < 200, < 350 and all PLHIV in the Rufiji district of Tanzania from 2006 to 2010.

Methods

The numbers of people on ART and pre-ART care were obtained from routinely aggregated, patient-level, cohort data from care and treatment centers in the district. We used ALPHA model to predict the number in need of pre-ART care and ART by age and sex at CD4 < 200 and < 350.

Results

Adult ART coverage among PLHIV increased from 2.9% in 2006 to 17.6% in 2010. In 2010, coverage was 20% for women and 14.8% for men. ART coverage was 30.2% and 38.7% in 2010 with reference to CD4 criteria of 350 and 200 respectively. In 2010, ART coverage was 0 and 3.4% among young people aged 15–19 and 20–24 respectively. ART coverage among females aged 35–39 and 40–44 was 30.6 and 35% respectively in 2010. Adult pre-ART care coverage for PLHIV of CD4 < 350 increased from 5% in 2006 to 37.7% in 2010. The age-sex coverage patterns for pre-ART care were similar to ART coverage for both CD4 of 200 and 350 over the study period.

Conclusions

ART coverage in the Rufiji district is unevenly distributed and far from the universal coverage target of 80%, in particular among young men. The findings in 2010 are close to the most recent estimates of ART coverage in 2013. To strive for universal coverage, both the recruitment of new eligible individuals to pre-ART and ART and the successful retention of those already on ART in the program need to be prioritized.
Literature
1.
go back to reference United Republic of Tanzania. Report of the 3 by 5 mission to Tanzania on scaling up antiretroviral treatment as part of the global emergency response to HIV/ AIDS. Dar es Salaam, Tanzania: Ministry of Health and Social Welfare publication; 2003. United Republic of Tanzania. Report of the 3 by 5 mission to Tanzania on scaling up antiretroviral treatment as part of the global emergency response to HIV/ AIDS. Dar es Salaam, Tanzania: Ministry of Health and Social Welfare publication; 2003.
3.
go back to reference Marston M, Michael D, Wringe A, Isingo R, Clark BD, Jonas A, et al. The impact of antiretroviral therapy on adult mortality in rural Tanzania. Trop Med Int Health. 2012;17:e58–65.CrossRefPubMedPubMedCentral Marston M, Michael D, Wringe A, Isingo R, Clark BD, Jonas A, et al. The impact of antiretroviral therapy on adult mortality in rural Tanzania. Trop Med Int Health. 2012;17:e58–65.CrossRefPubMedPubMedCentral
4.
go back to reference Bor J, Herbst AJ, Newell M-L, Bärnighausen T. Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatment. Science. 2013;339:961–5.CrossRefPubMed Bor J, Herbst AJ, Newell M-L, Bärnighausen T. Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatment. Science. 2013;339:961–5.CrossRefPubMed
6.
go back to reference Somi G, Matee M, Makene CL, Van Den Hombergh J, Kilama B. Three years of HIV / AIDS care and treatment services in Tanzania. Tanzan J Health Res. 2009;11:136–43.CrossRefPubMed Somi G, Matee M, Makene CL, Van Den Hombergh J, Kilama B. Three years of HIV / AIDS care and treatment services in Tanzania. Tanzan J Health Res. 2009;11:136–43.CrossRefPubMed
10.
go back to reference Gupta S, Williams B, Montaner J. Realizing the potential of treatment as prevention : global ART policy and treatment coverage. Curr HIV/AIDS Rep. 2014;11:479–86.CrossRefPubMed Gupta S, Williams B, Montaner J. Realizing the potential of treatment as prevention : global ART policy and treatment coverage. Curr HIV/AIDS Rep. 2014;11:479–86.CrossRefPubMed
11.
go back to reference Ying R, Barnabas RV, Williams BG. Modeling the implementation of Universal Coverage for HIV treatment as prevention and its impact on the HIV epidemic. Curr HIV/AIDS Rep. 2014;11:459–67.CrossRefPubMedPubMedCentral Ying R, Barnabas RV, Williams BG. Modeling the implementation of Universal Coverage for HIV treatment as prevention and its impact on the HIV epidemic. Curr HIV/AIDS Rep. 2014;11:459–67.CrossRefPubMedPubMedCentral
12.
go back to reference Arkin E. 0056. UN: political declaration on HIV and AIDS aims to intensify efforts to combat the epidemic. HIV AIDS Policy Law Rev. 2011;15:34–5.PubMed Arkin E. 0056. UN: political declaration on HIV and AIDS aims to intensify efforts to combat the epidemic. HIV AIDS Policy Law Rev. 2011;15:34–5.PubMed
17.
go back to reference Stover J, Walker N, Grassly NC, Marston M. Projecting the demographic impact of AIDS and the number of people in need of treatment: updates to the Spectrum projection package. Sex Transm Infect. 2006;82 Suppl 3:iii45–50.PubMedPubMedCentral Stover J, Walker N, Grassly NC, Marston M. Projecting the demographic impact of AIDS and the number of people in need of treatment: updates to the Spectrum projection package. Sex Transm Infect. 2006;82 Suppl 3:iii45–50.PubMedPubMedCentral
18.
go back to reference Mahy M, Lewden C, Brinkhof MWG, Dabis F, Tassie J-M, Souteyrand Y, et al. Derivation of parameters used in Spectrum for eligibility for antiretroviral therapy and survival on antiretroviral therapy. Sex Transm Infect. 2010;86 Suppl 2 Suppl 2:ii28–34.PubMed Mahy M, Lewden C, Brinkhof MWG, Dabis F, Tassie J-M, Souteyrand Y, et al. Derivation of parameters used in Spectrum for eligibility for antiretroviral therapy and survival on antiretroviral therapy. Sex Transm Infect. 2010;86 Suppl 2 Suppl 2:ii28–34.PubMed
20.
go back to reference Todd J, Glynn JR, Marston M, Lutalo T, Biraro S, Mwita W, et al. Time from HIV seroconversion to death : a collaborative analysis of eight studies in six low and middle-income countries before highly active antiretroviral therapy. AIDS. 2007;21:55–63.CrossRef Todd J, Glynn JR, Marston M, Lutalo T, Biraro S, Mwita W, et al. Time from HIV seroconversion to death : a collaborative analysis of eight studies in six low and middle-income countries before highly active antiretroviral therapy. AIDS. 2007;21:55–63.CrossRef
21.
go back to reference Zaba B, Kasamba I, Floyd S, Isingo R, Herbst K, Bärnighausen T, et al. Using age-specific mortality of HIV infected persons to predict anti-retroviral treatment need: a comparative analysis of data from five African population-based cohort studies. Trop Med Int Health. 2012;17:e3–14.CrossRefPubMedPubMedCentral Zaba B, Kasamba I, Floyd S, Isingo R, Herbst K, Bärnighausen T, et al. Using age-specific mortality of HIV infected persons to predict anti-retroviral treatment need: a comparative analysis of data from five African population-based cohort studies. Trop Med Int Health. 2012;17:e3–14.CrossRefPubMedPubMedCentral
22.
23.
go back to reference Mugglin C, Estill J, Wandeler G, Bender N, Egger M, Gsponer T, et al. Loss to programme between HIV diagnosis and initiation of antiretroviral therapy in sub-Saharan Africa: systematic review and meta-analysis. Trop Med Int Health. 2012;17:1509–20.CrossRefPubMedPubMedCentral Mugglin C, Estill J, Wandeler G, Bender N, Egger M, Gsponer T, et al. Loss to programme between HIV diagnosis and initiation of antiretroviral therapy in sub-Saharan Africa: systematic review and meta-analysis. Trop Med Int Health. 2012;17:1509–20.CrossRefPubMedPubMedCentral
24.
go back to reference National Bureau of Statistics (NBS) and Office of Chief Government Statistician (OCGS) Zanzibar publication. 2012 Population and housing census: population distribution by administrative area. Dar es Salaam, Tanzania: NBS and OCGS publication; 2013. National Bureau of Statistics (NBS) and Office of Chief Government Statistician (OCGS) Zanzibar publication. 2012 Population and housing census: population distribution by administrative area. Dar es Salaam, Tanzania: NBS and OCGS publication; 2013.
25.
go back to reference Tanzania Commission for AIDS (TACAIDS), Zanzibar AIDS Commission (ZAC), National Bureau of Statistics (NBS), Office of the Chief Government Statistician (OCGS), and ICF International 2013. Tanzania HIV/AIDS and Malaria Indicator Survey 2011-12. Dar es Salaam Tanzania: TACAIDS, ZAC, NBS, OCGS, and ICF International publication; 2013. Tanzania Commission for AIDS (TACAIDS), Zanzibar AIDS Commission (ZAC), National Bureau of Statistics (NBS), Office of the Chief Government Statistician (OCGS), and ICF International 2013. Tanzania HIV/AIDS and Malaria Indicator Survey 2011-12. Dar es Salaam Tanzania: TACAIDS, ZAC, NBS, OCGS, and ICF International publication; 2013.
26.
go back to reference Tanzania Commission for AIDS (TACAIDS), Zanzibar AIDS Commission (ZAC), National Bureau of Statistics (NBS), Office of the Chief Government Statistician (OCGS), and Macro International Inc. Tanzania HIV/AIDS and malaria indicator survey 2007-08. Dar es Salaam, Tanzania: TACAIDS, ZAC, NBS, OCGS, and Macro International Inc; 2008. Tanzania Commission for AIDS (TACAIDS), Zanzibar AIDS Commission (ZAC), National Bureau of Statistics (NBS), Office of the Chief Government Statistician (OCGS), and Macro International Inc. Tanzania HIV/AIDS and malaria indicator survey 2007-08. Dar es Salaam, Tanzania: TACAIDS, ZAC, NBS, OCGS, and Macro International Inc; 2008.
27.
go back to reference Agnarson AM, Masanja H, Ekström AM, Eriksen J, Tomson G, Thorson A. Challenges to ART scale-up in a rural district in Tanzania: stigma and distrust among Tanzanian health care workers, people living with HIV and community members. Trop Med Int Health. 2010;15:1000–7.PubMed Agnarson AM, Masanja H, Ekström AM, Eriksen J, Tomson G, Thorson A. Challenges to ART scale-up in a rural district in Tanzania: stigma and distrust among Tanzanian health care workers, people living with HIV and community members. Trop Med Int Health. 2010;15:1000–7.PubMed
28.
go back to reference Agnarson AM, Levira F, Masanja H, Ekström AM, Thorson A. Antiretroviral treatment knowledge and stigma–implications for programs and HIV treatment interventions in rural Tanzanian populations. PLoS One. 2013;8:e53993.CrossRefPubMedPubMedCentral Agnarson AM, Levira F, Masanja H, Ekström AM, Thorson A. Antiretroviral treatment knowledge and stigma–implications for programs and HIV treatment interventions in rural Tanzanian populations. PLoS One. 2013;8:e53993.CrossRefPubMedPubMedCentral
29.
go back to reference Wandel S, Egger M, Rangsin R, Nelson KE, Costello C, Lewden C, et al. Duration from seroconversion to eligibility for antiretroviral therapy and from ART eligibility to death in adult HIV-infected patients from low and middle-income countries: collaborative analysis of prospective studies. Sex Transm Infect. 2008;84(Suppl 1(Suppl I)):i31–6.PubMed Wandel S, Egger M, Rangsin R, Nelson KE, Costello C, Lewden C, et al. Duration from seroconversion to eligibility for antiretroviral therapy and from ART eligibility to death in adult HIV-infected patients from low and middle-income countries: collaborative analysis of prospective studies. Sex Transm Infect. 2008;84(Suppl 1(Suppl I)):i31–6.PubMed
30.
go back to reference Van der Paal L, Shafer LA, Todd J, Mayanja BN, Whitworth JAG, Grosskurth H. HIV-1 disease progression and mortality before the introduction of highly active antiretroviral therapy in rural Uganda. AIDS. 2007;21 Suppl 6:S21–9.CrossRefPubMed Van der Paal L, Shafer LA, Todd J, Mayanja BN, Whitworth JAG, Grosskurth H. HIV-1 disease progression and mortality before the introduction of highly active antiretroviral therapy in rural Uganda. AIDS. 2007;21 Suppl 6:S21–9.CrossRefPubMed
31.
go back to reference Zaba B, Marston M, Crampin AC, Isingo R, Biraro S, Bärnighausen T, et al. Age-specific mortality patterns in HIV-infected individuals: a comparative analysis of African community study data. AIDS. 2007;21 Suppl 6:S87–96.CrossRefPubMed Zaba B, Marston M, Crampin AC, Isingo R, Biraro S, Bärnighausen T, et al. Age-specific mortality patterns in HIV-infected individuals: a comparative analysis of African community study data. AIDS. 2007;21 Suppl 6:S87–96.CrossRefPubMed
32.
go back to reference TACAIDS. Ungass reportiing for 2010. Tanzania: Dar es Salaam; 2010. TACAIDS. Ungass reportiing for 2010. Tanzania: Dar es Salaam; 2010.
33.
go back to reference Le Coeur S, Collins IJ, Pannetier J, Lelièvre E. Gender and access to HIV testing and antiretroviral treatments in Thailand: why do women have more and earlier access? Soc Sci Med. 2009;69:846–53.CrossRefPubMed Le Coeur S, Collins IJ, Pannetier J, Lelièvre E. Gender and access to HIV testing and antiretroviral treatments in Thailand: why do women have more and earlier access? Soc Sci Med. 2009;69:846–53.CrossRefPubMed
34.
go back to reference Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376:41–8.CrossRefPubMed Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376:41–8.CrossRefPubMed
35.
go back to reference Peltzer K, Matseke G, Mzolo T, Majaja M. Determinants of knowledge of HIV status in South Africa: results from a population-based HIV survey. BMC Public Health. 2009;9:174.CrossRefPubMedPubMedCentral Peltzer K, Matseke G, Mzolo T, Majaja M. Determinants of knowledge of HIV status in South Africa: results from a population-based HIV survey. BMC Public Health. 2009;9:174.CrossRefPubMedPubMedCentral
37.
go back to reference Kurowski C, Wyss K, Abdulla S, Mills A. Scaling up priority health interventions in Tanzania: the human resources challenge. Health Policy Plan. 2007;22:113–27.CrossRefPubMed Kurowski C, Wyss K, Abdulla S, Mills A. Scaling up priority health interventions in Tanzania: the human resources challenge. Health Policy Plan. 2007;22:113–27.CrossRefPubMed
38.
go back to reference Somi G, Keogh SC, Todd J, Kilama B, Wringe A, van den Hombergh J, et al. Low mortality risk but high loss to follow-up among patients in the Tanzanian national HIV care and treatment programme. Trop Med Int Health. 2012;17:497–506.CrossRefPubMed Somi G, Keogh SC, Todd J, Kilama B, Wringe A, van den Hombergh J, et al. Low mortality risk but high loss to follow-up among patients in the Tanzanian national HIV care and treatment programme. Trop Med Int Health. 2012;17:497–506.CrossRefPubMed
39.
go back to reference Van Damme W, Kober K, Kegels G. Scaling-up antiretroviral treatment in Southern African countries with human resource shortage: how will health systems adapt? Soc Sci Med. 2008;66:2108–21.CrossRefPubMed Van Damme W, Kober K, Kegels G. Scaling-up antiretroviral treatment in Southern African countries with human resource shortage: how will health systems adapt? Soc Sci Med. 2008;66:2108–21.CrossRefPubMed
Metadata
Title
Antiretroviral treatment coverage in a rural district in Tanzania – a modeling study using empirical data
Authors
Francis Levira
Abela Mpobela Agnarson
Honorati Masanja
Basia Zaba
Anna Mia Ekström
Anna Thorson
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-1460-8

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