Published in:
01-09-2015 | Reproductive Physiology and Disease
Antimullerian hormone levels are inversely associated with body mass index (BMI) in women with polycystic ovary syndrome
Authors:
Maya Kriseman, Charity Mills, Ertug Kovanci, Haleh Sangi-Haghpeykar, William Gibbons
Published in:
Journal of Assisted Reproduction and Genetics
|
Issue 9/2015
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Abstract
Purpose
The purpose of this paper is to determine whether antimullerian hormone (AMH) levels were associated with BMI in patients with diagnosed infertility, and more specifically, in patients with polycystic ovarian syndrome (PCOS).
Methods
A retrospective cohort study reviewed all females who presented to the clinical investigators’ practice between November 2011 and March 2013. The following data was retrieved from the medical record: (1) AMH level, (2) age, (3) BMI, (4) ethnicity, and (5) if infertile, etiology of infertility.
Results
AMH levels were available for 489 women. Of these, 104 were diagnosed with PCOS. Overall, there was no association between BMI and AMH (r −0.04, p > 0.05). On the other hand, in the women with PCOS, there was a significant association between BMI and AMH (r −0.31, p < 0.01).
Conclusions
BMI was not associated with AMH levels in the general population of infertile women or in patients without PCOS. However, BMI appeared to be significantly and inversely correlated with AMH in women with PCOS.