Top

European Journal of Clinical Microbiology & Infectious Diseases

Published in:

01-11-2015 | Review

Antimicrobial stewardship policy: time to revisit the strategy?

Authors: P.-M. Roger, J. Courjon, S. Léotard, C. Déchamp, N. Négrin, M. Vassallo, Réseau d’Infectiologie Paca-Est

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 11/2015

Abstract

Recent data indicate that both the overall numbers of antibiotic prescription and the frequency of multidrug-resistant bacteria are increasing significantly. These threatening features are observed, despite national antimicrobial stewardship (AMS) policies aimed at decreasing antibiotic use. AMS should also focus on the initial steps leading to antibiotic prescription. Physicians and their patients should benefit from the structured clinical pathways, the latter being adapted to regional epidemiological data and resources. Continuous evaluation of these predefined clinical paths through a computerized medical dashboard will allow a critical review and finally the optimization of medical practices. These innovative behavioural approaches for clinicians will supply precise information on the relationship among the diagnosis, therapeutics and outcome. This changing environment will carry out the adapted therapeutic procedures, and appropriate antibiotic use will inherently improve.

Levy HG (2014) Antimicrobial stewardship in hospitals: does it work and can we do it? J Glob Antimicrob Resist 2:1–6CrossRef

Roca I, Akova M, Baquero F et al (2015) The global threat of antimicrobial resistance: science for intervention. New Microbes New Infect 16(6):22–29CrossRef

Thabit AK, Crandon JL, Nicolau DP (2015) Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials. Expert Opin Pharmacother 16:159–177CrossRefPubMed

Brakov N, Morgan DJ, Schweizer ML et al (2014) Assessment of empirical therapy in six hospitals: an observational cohort study. Lancet Infect Dis 14:1220–1227CrossRef

Chen C, James R, Cotta M, Buising K, Marhall C, Thursky K (2015) Towrds effective antimicrobial surveillance: results of the National Antimicrobial Prescribing Survey, a snapshot audit of prescribing practices in Australian hospitals. 25th ECCMID Copenhagen, Denmark

Howard P, Pulcini C, Levy Hara G, West RM, Gould IM, Harbarth S, Nathwani D (2015) An international cross-sectional survey of antimicrobial stewardship programmes in hospitals. J Antimicrob Chemother 70:1245–1255PubMed

Pestonik SL, Classen DC, Evans RS, Burke JP (1996) Implementing antibiotic practice guidelines through computer-assisted decision support: clinical and financial outcomes. Ann Intern Med 124:884–890CrossRef

Miliani K, L’Hériteau F, Alfandari S et al (2008) Specific control measures for antibiotic prescription are related to lower consumption in hospitals: results from a French multicentre pilot study. J Antimicrob Chemother 62:823–829CrossRefPubMed

Lesprit P, Brun-Buisson C (2008) Hospital antibiotic stewardship. Curr Opin Infect Dis 21:344–349CrossRefPubMed

10.

Charani E, Castro-Sanchez E, Seydalis N et al (2013) Understanding the determinants of antimicrobial Prescribing within hospitals: the role of “prescribing etiquette”. Clin Infect Dis 57:188–196PubMedCentralCrossRefPubMed

11.

Cook PP, Gooch M (2015) Long-term effects of an antimicrobial stewardship programme at a tertiary-care teaching hospital. Int J Antimicrob Agents 45:262–267CrossRefPubMed

12.

Pollack LA, Srinivasan A (2014) Core elements of hospital antibiotic stewardship programs from the centers for Disease Control and Prevention. Clin Infect Dis 59(S3):97–100CrossRef

13.

DePestel DD, Eiland EH, Lusardi K et al (2014) Assessing appropriateness of antimicrobial therapy: in the eye of the interpreter. Clin Infect Dis 59(S3):154–161CrossRef

14.

Pulcini C, Gyssens IC (2013) How to educate prescribers in antimicrobial stewardship practices. Virulence 4:192–202PubMedCentralCrossRefPubMed

15.

Holmes AH (2015) Behavioural science applications in antimicrobial stewardship and infection control. 25th ECCMID Copenhagen, Denmark

16.

Charani E, Gharbi M, Moore LS, Castro-Sanchez E, Gilchrist M, Holmes AH (2015) The effect of a smartphone application on antimicrobial prescribing trends. Data from a multifaceted antimicrobial stewardship programme across three teaching hospitals. 25th ECCMID Copenhagen, Denmark

17.

Dinh A, Grenet J, Beauchet A et al (2015) Do we need antimicrobial stewardship in the emergency room department for outpatients? 25th ECCMID Copenhagen, Denmark

18.

Dumartin C, Rogues A, Pefau M et al (2015) Worring trends in antibiotic use in French Hospitals, 2008–2013. 25th ECCMID Copenhagen, Denmark

19.

Etienne P, Roger PM, Brofferio P et al (2011) Antimicrobial stewardship program and quality of antibiotic prescriptions. Med Mal Infect 41:608–612CrossRefPubMed

20.

Singh N, Rogers P, Atwood CW et al (2000) Short course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. Am J Respir Crit Care 162:505–511CrossRef

21.

Pulcini C, Pradier C, Samat-Long C et al (2006) Factors associated with adherence to infectious diseases advice in two intensive care units. J Antimicrob Chemother 57:546–550CrossRefPubMed

22.

Garnacho-Montero J, Gutierrez-Pizarraya A, Escoresca-Ortega A et al (2014) De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med 40:32–40CrossRefPubMed

23.

Capelastegui A, Espana PP, Quintana JM et al (2004) Improvement of process-of-care and outcomes after implementing a guideline for the management of community-acquired pneumonia: a controlled before and after design study. Clin Infect Dis 39:955–963CrossRefPubMed

24.

Pradelli J, Risso K, Guillouet de salavdor F et al (2015) Community-acquired pneumonia: impact of empirical antibiotic therapy without respiratory fluoroquinolones nor third generation cephalosporins. Eur J Clin Microb Infect Dis 34:511–518CrossRef

25.

Mothes A, Del Guidice P, Smets A et al (2015) Severe community-acquired pneumonia and positive urinary antigen test: antibiotic simplification is associated with an increase of patients survival rate. ePoster 024. European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) Copenhagen

26.

Roger PM, Farhad R, Leroux S et al (2008) Computerized management of a medical department, disease-related group management, clinical research and evaluations. Med Mal Infect 38:457–464CrossRefPubMed

27.

Farhad R, Roger PM, Albert C et al (2010) Six weeks antibiotic therapy for all bone infections: results of a cohort study Eur J Clin Microbiol Infect Dis 29:217–22

Title: Antimicrobial stewardship policy: time to revisit the strategy?
Authors: P.-M. Roger
J. Courjon
S. Léotard
C. Déchamp
N. Négrin
M. Vassallo
Réseau d’Infectiologie Paca-Est
Publication date: 01-11-2015
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 11/2015
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-015-2483-x

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 11/2015

Rapid molecular diagnostic tests in patients with bacteremia: evaluation of their impact on decision making and clinical outcomes

Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo

Contribution of IL6 −174 G>C and IL1B +3954 C>T polymorphisms to congenital infection with Toxoplasma gondii

Low serum hyaluronic acid levels associated with spontaneous HBsAg clearance

Assessment of a molecular diagnostic platform for integrated isolation and quantification of mRNA in whole blood

Routine disc diffusion antimicrobial susceptibility testing of Clostridium difficile and association with PCR ribotype 027

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials