Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
BMC Complementary Medicine and Therapies
Published in: BMC Complementary Medicine and Therapies 1/2015

Open Access 01-12-2015 | Research article

Antimicrobial potential of 27 plants consumed by chimpanzees (Pan troglodytes verus Blumenbach) in Ivory Coast

Authors: Angora Rémi Constant Ahoua, Amoin Georgette Konan, Bassirou Bonfoh, Mamidou Witabouna Koné

Published in: BMC Complementary Medicine and Therapies | Issue 1/2015

Login to get access

Abstract

Background

Due to their genetic proximity, chimpanzees share with human several diseases including bacterial, fungal and viral infections, such as candidiasis, acquired immune deficiency syndrome (AIDS), Ebola virus disease. However, in its natural environment, chimpanzees are tolerant to several pathogens including simian immunodeficiency virus (SIV), virus related to human immunodeficiency virus (HIV) that contribute to the emergence of opportunistic diseases such as microbial infections.

Methods

Twenty seven species of plants consumed by chimpanzees were evaluated for their antimicrobial potential against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Candida tropicalis and Candida glabrata using the agar diffusion technique and micro-dilution in 96-well plates. In total 132 extracts (33 dichloromethane, 33 methanol, 33 ethyl acetate and 33 aqueous) were tested.

Results

The results showed that 24 extracts (18 %) showed activity against bacteria and 6 extracts (5 %) were active against yeasts. The minimal inhibitory concentrations (MICs) values of active extracts ranged between 23 and 750 μg/ml for bacteria and between 188 and 1500 μg/ml for yeasts.

Conclusion

Tristemma coronatum was the most promising on the studied microorganisms followed by Beilschmiedia mannii. The extracts of the two plants indicated by chimpanzees have potential for antimicrobial use in human.
Literature
1.
Diallo A. Etude de la phytochimie et des activités biologiques de Syzygium guineense Willd. (Myrtaceae), Thèse. Université de Bamako, Mali: Faculté de Médecine, de Pharmacie et d’Odoto-Stomatologie; 2005.
2.
3.
Chanda S, Rakholiya K. Combination therapy: Synergism between natural plant extracts and antibiotics against infectious diseases. In: Méndez-Vials A, editor. Science against microbiology pathogens: communicating current research and technological advances, Microbiology book series, Formatex Research Center. 2011. p. 520–9.
4.
Soro D, Kone MW, Kamanzi K. Evaluation des activités antimicrobiennes et anti-radicaux libres de quelques taxons bioactifs de Côte d’Ivoire. Eur J Sci Res. 2010;40:307–17.
5.
Akinyemi KO, Oladapo O, Okwara CE, Ibe CC, Fasure KA. Screening of crude extracts of six medicinal plants used in South-West Nigerian unorthodox medicine for anti-methicillin resistant Staphylococcus aureus activity. BMC Complement Altern Med. 2005;5:6.PubMedCentralCrossRefPubMed
6.
Akoua-Koffi C, Guessennd N, Gbonon V, Faye-Ketté H, Dosso M. Methicillin-resistance of Staphylococcus aureus in Abidjan (1998–2001): a new hospital problem. Med Mal Infect. 2004;34:132–6.CrossRefPubMed
7.
Balkis MM, Leidich SD, Mukherjee PK, Ghannoum MA. Mechanisms of fungal resistance: an overview. Drugs. 2002;62:1025–40.CrossRefPubMed
8.
Benbachir M, Benredjeb S, Boye CS, Dosso M, Belabbes H, Kamoun A, et al. Two-year surveillance of antibiotic resistance in Streptococcus pneumoniae in four African cities. Antimicrob Agents Chemother. 2001;45:627–9.PubMedCentralCrossRefPubMed
9.
Ju J, Polhamus C, Marr K, Holland S, Bennett JE. Efficacies of fluconazole, caspofungin, and amphotericin B in Candida glabrata-infected p47phox−/−knockout mice. Antimicrob Agents Chemother. 2002;46:1240–5.PubMedCentralCrossRefPubMed
10.
Kacou-N’Douba A, Bouzid SA, Guessennd KN, Kouassi-M’Bengue AA, Faye-Kette AY, Dosso M. Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae in healthy carriers: report of a study in 5-year-olds in Marcory, Abidjan, Côte d’Ivoire. Ann Trop Paediatr. 2001;21:149–54.CrossRefPubMed
11.
Ramage G, Bachmann S, Patterson T, Wickes B, López-Ribot J. Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms. J Antimicrob Chemother. 2002;49:973–80.CrossRefPubMed
12.
Rodero L, Cuenca-Estrella M, Cordoba S, Cahn P, Davel G, Kaufman S, et al. Transient fungemia caused by an amphotericin B-resistant isolate of Candida haemulonii. J Clin Microbiol. 2002;40:2266–9.PubMedCentralCrossRefPubMed
13.
14.
15.
Guessennd N, Gbonon V, Tiékoura K, Kakou-N’douba A, Ouattara D, Boni-Cissé C, et al. Evolution de la résistance bactérienne à l’imipénème en Côte d’Ivoire de 2005 à 2009, Colloque scientifique de l’Institut Pasteur de Côte d’Ivoire: pathologies émergentes et biologie intégrative. 2009.
16.
Senhaji O, Faid M, Elyachioui M, Dehhaoui M. Étude de l’activité antifongique de divers extraits de cannelle. J Mycol Med. 2005;15:220–9.CrossRef
17.
Atindehou K, Koné M, Terreaux C, Traoré D, Hostettmann K, Dosso M. Evaluation of the antimicrobial potential of medicinal plants from the Ivory Coast. Phytother Res. 2002;16:497–502.CrossRefPubMed
18.
Koné WM, Atindéhou KK, Terreaux C, Hostettmann K, Traore D, Dosso M. Traditional medicine in North Cote-d’Ivoire: screening of 50 medicinal plants for antibacterial activity. J Ethnopharmacol. 2004;93:43–9.CrossRefPubMed
19.
Kouadio F, Guessennd N, Karamoko O, Bahi C, Adama C, Dosso M. Action antibactérienne de l’extrait éthanolique 70 % de Clerodendrum splendens (G. Don) (Verbenacae) sur des souches bactériennes isolées de selles chez des enfants diarrhéiques. Inter J Biol Chem Sci. 2013;7:1332–7.CrossRef
20.
Tra Bi FH, Koné MW, Kouamé NF. Antifungal activity of Erigeron floribundus (Asteraceae) from Côte d’Ivoire, West Africa. Trop J Pharm Res. 2008;7:975–9.CrossRef
21.
Sibley CG, Ahlquist JE. The phylogeny of the hominoid primates, as indicated by DNA-DNA hybridization. J Mol Evol. 1984;20:2–15.CrossRefPubMed
22.
Kurth R, Norley S. Why don’t the natural hosts of SIV develop simian AIDS? J NIH Res. 1996;8:33–7.
23.
24.
25.
26.
Ahoua ARC, Koné MW, Konan AG, Tra Bi FH, Bonfoh B. Antioxidant activity of eight plants consumed by great apes in Côte d’Ivoire. Afr J Biotechnol. 2012;11:11732–40.
27.
28.
Zinsstag J, Schelling E, Roth F, Bonfoh B, de Savigny D, Tanner M. Human benefits of animal interventions for zoonosis control. Emerg Infect Dis. 2007;13:527–31.PubMedCentralCrossRefPubMed
29.
Zinsstag J, Schelling E, Wyss K, Mahamat MB. Potential of cooperation between human and animal health to strengthen health systems. Lancet. 2005;366:2142–5.CrossRefPubMed
30.
N’Guessan KA. Aspects quantitatifs et qualitatifs du régime alimentaire des chimpanzés (Pan Troglodytes Verus, Blumenbach 1779) au Parc National De Taï, Côte D’Ivoire, Thèse. Université Félix Houphouët-Boigny–Cocody, Abidjan Côte d’Ivoire: UFR Biosciences; 2012.
31.
Kamanzi A. Plantes médicinales de Côte d’Ivoire: investigations phytochimiques guidées par des essais biologiques, Thèse. Université de Cocody-Abidjan (Côte d’Ivoire): UFR Biosciences; 2002.
32.
Rakotoniriana EF, Rajaonarison JF, Raoelison EG, Rajaonarivelo JP, Manga N, Solofoniaina M, et al. Antimicrobial activity of 23 endemic plants in Madagascar. Trop J Pharm Res. 2010;9:165–71.CrossRef
33.
Statistica. Statistica pour Windows, release 5.5. France: Statoft Inc; 1999.
34.
Yao K, Koné M, Bonfoh B, Kamanzi K. Antioxidant activity and total phenolic content of nine plants from Côte d’Ivoire (West Africa). J Appl Pharm Sci. 2014;4:36–41.
35.
Fankam AG, Kuiate JR, Kuete V. Antibacterial activities of Beilschmiedia obscura and six other Cameroonian medicinal plants against multi-drug resistant Gram-negative phenotypes. BMC Complement Altern Med. 2014;14:241.PubMedCentralCrossRefPubMed
36.
Chouna JR, Nkeng-Efouet PA, Lenta BN, Devkota KP, Neumann B, Stammler H-G, et al. Antibacterial endiandric acid derivatives from Beilschmiedia anacardioides. Phytochemistry. 2009;70:684–8.CrossRefPubMed
37.
Paulo Mde Q, Barbosa-Filho J, Lima E, Maia R, Barbosa Rde C, Kaplan M. Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C. J Ethnopharmacol. 1992;36:39–41.CrossRefPubMed
38.
Fitzgerald DJ, Stratford M, Gasson MJ, Narbad A. Structure-function analysis of the vanillin molecule and its antifungal properties. J Agric Food Chem. 2005;53:1769–75.CrossRefPubMed
39.
Lenta BN, Tantangmo F, Devkota KP, Wansi JD, Chouna JR, Soh RC, et al. Bioactive constituents of the stem bark of Beilschmiedia zenkeri. J Nat Prod. 2009;72:2130–4.CrossRefPubMed
40.
Park J, Lee J, Jung E, Park Y, Kim K, Park B, et al. In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp. Eur J Pharmacol. 2004;496:189–95.CrossRefPubMed
41.
Sugiyama Y, Koman J. A preliminary list of chimpanzees’ alimentation at Bossou, Guinea. Primates. 1987;28:133–47.CrossRef
42.
Kouamé N, Gnahoua G, Kouassi KE, Traore D. Plantes alimentaires spontanées de la région du Fromager (Centre-Ouest de la Côte d’Ivoire): flore, habitats et organes consommés. Sci Nat. 2008;5:61–70.
43.
Wansi JD, Chiozem DD, Tcho AT, Toze FAA, Devkota KP, Ndjakou BL, et al. Antimicrobial and antioxidant effects of phenolic constituents from Klainedoxa gabonensis. Pharm Biol. 2010;48:1124–9.CrossRefPubMed
44.
Bouquet A. Traditional doctors and traditional medicines of Congo Brazzaville. Paris: Orstom; 1969.
45.
Onanga M, Ekouya A, Ouabonzi A, Itoua GB. Ethnobotanical, pharmacological and chemical studies of plants used in the treatment of ‘Mwandza’dermatites. Fitoterapia. 1999;70:579–85.CrossRef
Metadata
Title
Antimicrobial potential of 27 plants consumed by chimpanzees (Pan troglodytes verus Blumenbach) in Ivory Coast
Authors
Angora Rémi Constant Ahoua
Amoin Georgette Konan
Bassirou Bonfoh
Mamidou Witabouna Koné
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Complementary Medicine and Therapies / Issue 1/2015
Electronic ISSN: 2662-7671
DOI
https://doi.org/10.1186/s12906-015-0918-7

Other articles of this Issue 1/2015

BMC Complementary Medicine and Therapies 1/2015 Go to the issue

Research article

The Chinese medicine Sini-San inhibits HBx-induced migration and invasiveness of human hepatocellular carcinoma cells

Research article

Electroacupuncture at different frequencies (5Hz and 25Hz) ameliorates cerebral ischemia-reperfusion injury in rats: possible involvement of p38 MAPK-mediated anti-apoptotic signaling pathways

Erratum

Erratum to: Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice

Research article

Transcendental Meditation for the improvement of health and wellbeing in community-dwelling dementia caregivers [TRANSCENDENT]: a randomised wait-list controlled trial

Research article

Ethnic differences in medicinal plant use among University students: a cross-sectional survey of self-reported medicinal plant use at two Midwest Universities

Research article

Alkanna tinctoria leaves extracts: a prospective remedy against multidrug resistant human pathogenic bacteria