01-11-2011 | Clinical Research
Antidepressant Drug Therapy Does Not Affect Weight Loss One Year after Gastric Bypass Surgery
Published in: Obesity Surgery | Issue 11/2011
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Background
Preliminary data suggest that patients with actively treated depression should expect the same outcomes after surgery. The objective of this study was to compare weight loss 12 months after gastric bypass surgery in patients taking antidepressants before surgery (AD) versus those who were not (non-AD).
Methods
IRB approval was obtained. All patients gave informed consent prior to participating in the study. Medication and weight loss histories were retrospectively reviewed in adult patients who were followed at 12 months post-surgery.
Results
145 of 364 patients were taking antidepressants at baseline. There was no significant difference in weight loss between the AD and non-AD groups at 12 months (p > 0.05).
Conclusions
Taking antidepressant medication prior to gastric bypass surgery did not affect weight loss outcomes at 12 months.