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Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 6/2019

01-06-2019 | Antibiotic | Original Article

Potential utility of bone scan in cranial bone flap osteomyelitis

Authors: Alexandre Bani Sadr, Bastien Gregoire, Jeremie Tordo, Jacques Guyotat, Andre Boibieux, Marc Janier

Published in: Annals of Nuclear Medicine | Issue 6/2019

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Abstract

Objective

Currently, the diagnosis of bone flap osteomyelitis (BFO) remains a challenge for medical imaging. The present study aimed to identify predictive scintigraphic patterns of BFO.

Methods

This retrospective study reviewed planar bone scan of patients with suspected BFO between 2010, and 2016. A total of 15 patients were included. Final diagnosis of BFO was obtained by histological and bacteriological documentation. Eight scintigraphic signs potentially helpful were reviewed and correlated with the final diagnosis individually or in combination through Fischer exact test.

Results

Eight patients out of 15 (53.3%) were diagnosed with BFO. Radionuclide uptake inside the bone flap during blood-pool phase was predictive for BFO (p = 0.007) with 75.0% sensitivity 100% specificity, and 86.7% accuracy. In combination, radionuclide uptake inside the bone flap or a spreading wavefront between blood-pool and delayed phases was associated with BFO (p = 0.007). It did not improve diagnostic performance.

Conclusion

Using well-defined and reproducible scintigraphic signs, bone scan is helpful for the diagnosis of BFO.
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Metadata
Title
Potential utility of bone scan in cranial bone flap osteomyelitis
Authors
Alexandre Bani Sadr
Bastien Gregoire
Jeremie Tordo
Jacques Guyotat
Andre Boibieux
Marc Janier
Publication date
01-06-2019
Publisher
Springer Singapore
Published in
Annals of Nuclear Medicine / Issue 6/2019
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-019-01351-y

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