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Chinese Medicine
Published in: Chinese Medicine 1/2011

Open Access 01-12-2011 | Review

Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia

Authors: Shan-Yu Su, Ching-Liang Hsieh

Published in: Chinese Medicine | Issue 1/2011

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Abstracts

Recent studies have demonstrated the importance of anti-inflammation, including cellular immunity, inflammatory mediators, reactive oxygen species, nitric oxide and several transcriptional factors, in the treatment of cerebral ischemia. This article reviews the roles of Chinese medicinal herbs as well as their ingredients in the inflammatory cascade induced by cerebral ischemia. Chinese medicinal herbs exert neuroprotective effects on cerebral ischemia. The effects include inhibiting the activation of microglia, decreasing levels of adhesion molecules such as intracellular adhesion molecule-1, attenuating expression of pro-inflammatory cytokines such as interleukin-1β and tumor necrosis factor-α, reducing inducible nitric oxide synthase and reactive oxygen species, and regulating transcription factors such as nuclear factor-κB.
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Metadata
Title
Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia
Authors
Shan-Yu Su
Ching-Liang Hsieh
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Chinese Medicine / Issue 1/2011
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/1749-8546-6-26

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