Published in:
Open Access
01-02-2011 | Poster presentation
Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and circulating ACE levels are not associated with outcome in septic critically ill patients
Authors:
I Tsangaris, A Tsantes, P Kopterides, G Tsaknis, G Antonakos, D Konstantonis, A Nikolaidou, E Vrigkou, A Tsante, A Anthi, S Orfanos, K Dima, A Armaganidis
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
Several studies of critically ill patients have suggested an association of the D/D genotype of the insertion/deletion (I/D) angiotensin-converting enzyme (ACE) polymorphism with poor outcome probably by enhancing the inflammatory response and leading to a procoagulant state. Our aim was to evaluate the effect of both the ACE I/D polymorphism and its gene product, on the clinical outcome of critically ill septic patients. …