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Acta Neurologica Belgica

Published in:

09-10-2022 | Angiography | Original article

Can bispectral index be an early marker in the diagnosis of brain death?

Authors: Yasemin Çoban, Dincer Yildizdas, Ozden Ozgur Horoz, Nagehan Aslan, Ozlem Herguner

Published in: Acta Neurologica Belgica | Issue 2/2023

Abstract

Background

The diagnosis of brain death is a clinical condition in which it is difficult to perform confirmatory tests due to the ineligible clinical status of the patient. Prior to confirmatory tests, the use of a BIS monitor to determine the time of brain death is important for organ transplants, cost-effectiveness and reducing stressful wait of the family.

Objective

This study aimed to use BIS monitoring for early detection of brain death.

Methods

BIS monitoring was performed in 12 patients who were clinically diagnosed with brain death in our intensive care unit during a two-year period.

Results

All patients had diffuse brain injury. The BIS score was zero in all patients. However, two patients could not be legally diagnosed with brain death because confirmatory tests could not be performed due to the clinical status. In one patient, the BIS score was zero and blood flow was present on the first computed tomography angiography of the brain; however, the cerebral blood flow was absent on the second imaging after two days.

Conclusion

It was believed that BIS monitoring could be a parameter to use for detection of brain death in patients with severe brain injury. However, future research is needed in this regard.

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Title: Can bispectral index be an early marker in the diagnosis of brain death?
Authors: Yasemin Çoban
Dincer Yildizdas
Ozden Ozgur Horoz
Nagehan Aslan
Ozlem Herguner
Publication date: 09-10-2022
Publisher: Springer International Publishing
Keywords: Angiography
Brain Death
Electroencephalography
Published in: Acta Neurologica Belgica / Issue 2/2023
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI: https://doi.org/10.1007/s13760-022-02105-w

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Springer Medicine

Can bispectral index be an early marker in the diagnosis of brain death?

Abstract

Background

Objective

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Methods

Results

Conclusion

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