Skip to main content
Top
Published in: BMC Neurology 1/2020

01-12-2020 | Angiography | Case report

A case of multiple Vertebrobasilar artery fenestration misdiagnosed as vertebral artery dissection

Authors: Feng Wang, Xiaokai Wang, Xiaohua Li, Huifeng Zheng, Zhiyong Zhang

Published in: BMC Neurology | Issue 1/2020

Login to get access

Abstract

Background

Fenestration of vertebra-basilar artery is an uncommon congenital vascular anomaly, which is identified by incidental findings on imaging in patients presented without related symptoms or in patients with intracerebral hemorrhage secondary to concomitant artery aneurysm or arteriovenous malformations. Yet, cases of fenestration being misdiagnosed as cerebral artery dissection have never been reported.

Case presentation

We present a patient of 66-year-old female with acute onset of dizziness after chiropractic manipulation of the neck. Neck computed tomography angiography (CTA) showed ‘double lumen’ sign and ‘intimal flap’ of the V1 segment of the vertebral artery, which led to the initial diagnosis of vertebral artery dissection (VAD). However, vertebral artery fenestration at V1 segment was eventually identified by multi-directional digital subtraction angiography (DSA). Interestingly, concomitant vertebral fenestration at V3 segment, basilar fenestration and basilar artery tip aneurysm was also revealed by DSA.

Conclusion

The triple fenestration at vertebrobasilar artery with basilar tip artery aneurysm is extremely rare, and the fenestration at the V1 segment of vertebral artery was easily misdiagnosed as VAD due to the similar imaging morphology.
Literature
1.
go back to reference Cooke DL, Stout CE, Kim WT, Kansagra AP, Yu JP, Gu A, et al. Cerebral arterial fenestrations. Interv Neuroradiol. 2014;20:261–74.CrossRef Cooke DL, Stout CE, Kim WT, Kansagra AP, Yu JP, Gu A, et al. Cerebral arterial fenestrations. Interv Neuroradiol. 2014;20:261–74.CrossRef
2.
go back to reference Gao LY, Guo X, Zhou JJ, Zhang Q, Fu J, Chen WJ, et al. Basilar artery fenestration detected with CT angiography. Eur Radiol. 2013;23:2861–7.CrossRef Gao LY, Guo X, Zhou JJ, Zhang Q, Fu J, Chen WJ, et al. Basilar artery fenestration detected with CT angiography. Eur Radiol. 2013;23:2861–7.CrossRef
3.
go back to reference Sogawa K, Kikuchi Y, O'uchi T, Tanaka M, Inoue T. Fenestrations of the basilar artery demonstrated on magnetic resonance angiograms: an analysis of 212 cases. Interv Neuroradiol. 2013;19:461–5.CrossRef Sogawa K, Kikuchi Y, O'uchi T, Tanaka M, Inoue T. Fenestrations of the basilar artery demonstrated on magnetic resonance angiograms: an analysis of 212 cases. Interv Neuroradiol. 2013;19:461–5.CrossRef
4.
go back to reference Polguj M, Podgórski M, Jędrzejewski K, Topol M, Majos A. Fenestration and duplication of the vertebral artery: the anatomical and clinical points of view. Clin Anat. 2013;26:933–43.CrossRef Polguj M, Podgórski M, Jędrzejewski K, Topol M, Majos A. Fenestration and duplication of the vertebral artery: the anatomical and clinical points of view. Clin Anat. 2013;26:933–43.CrossRef
5.
go back to reference Gard AP, Kebriaei MA, Thorell WE. Review of vertebral artery fenestration and novel extracranial fenestration. Clin Neurol Neurosurg. 2013;115:1107–9.CrossRef Gard AP, Kebriaei MA, Thorell WE. Review of vertebral artery fenestration and novel extracranial fenestration. Clin Neurol Neurosurg. 2013;115:1107–9.CrossRef
6.
go back to reference Fukuda K, Higashi T, Okawa M, Matsumoto J, Takano K, Inoue T. Utility of cone-beam computed tomography angiography for the assessment of vertebral artery dissection. J Clin Neurosci. 2018;48:76–80.CrossRef Fukuda K, Higashi T, Okawa M, Matsumoto J, Takano K, Inoue T. Utility of cone-beam computed tomography angiography for the assessment of vertebral artery dissection. J Clin Neurosci. 2018;48:76–80.CrossRef
7.
go back to reference Provenzale JM, Sarikaya B. Comparison of test performance characteristics of MRI, MR angiography, and CT angiography in the diagnosis of carotid and vertebral artery dissection: a review of the medical literature. AJR Am J Roentgenol. 2009;193:1167–74.CrossRef Provenzale JM, Sarikaya B. Comparison of test performance characteristics of MRI, MR angiography, and CT angiography in the diagnosis of carotid and vertebral artery dissection: a review of the medical literature. AJR Am J Roentgenol. 2009;193:1167–74.CrossRef
8.
go back to reference Engelter ST, Traenka C, Lyrer P. Dissection of cervical and cerebral arteries. Curr Neurol Neurosci Rep. 2017;17:59.CrossRef Engelter ST, Traenka C, Lyrer P. Dissection of cervical and cerebral arteries. Curr Neurol Neurosci Rep. 2017;17:59.CrossRef
9.
go back to reference Hanning U, Sporns PB, Schmiedel M, Ringelstein EB, Heindel W, Wiendl H, et al. CT versus MR techniques in the detection of cervical artery dissection. J Neuroimaging. 2017;27:607–12.CrossRef Hanning U, Sporns PB, Schmiedel M, Ringelstein EB, Heindel W, Wiendl H, et al. CT versus MR techniques in the detection of cervical artery dissection. J Neuroimaging. 2017;27:607–12.CrossRef
10.
go back to reference Gottesman RF, Sharma P, Robinson KA, Arnan M, Tsui M, Saber-Tehrani A, et al. Imaging characteristics of symptomatic vertebral artery dissection: a systematic review. Neurologist. 2012;18:255–60.CrossRef Gottesman RF, Sharma P, Robinson KA, Arnan M, Tsui M, Saber-Tehrani A, et al. Imaging characteristics of symptomatic vertebral artery dissection: a systematic review. Neurologist. 2012;18:255–60.CrossRef
11.
go back to reference Kim SJ, Nogueira RG, Haussen DC. Current understanding and gaps in research of carotid webs in ischemic strokes: a review. JAMA Neurol. 2018;76:355–61.CrossRef Kim SJ, Nogueira RG, Haussen DC. Current understanding and gaps in research of carotid webs in ischemic strokes: a review. JAMA Neurol. 2018;76:355–61.CrossRef
12.
go back to reference Uchino A, Saito N, Okada Y, Kozawa E, Nishi N, Mizukoshi W, et al. Fenestrations of the intracranial vertebrobasilar system diagnosed by MR angiography. Neuroradiology. 2012;54:445–50.CrossRef Uchino A, Saito N, Okada Y, Kozawa E, Nishi N, Mizukoshi W, et al. Fenestrations of the intracranial vertebrobasilar system diagnosed by MR angiography. Neuroradiology. 2012;54:445–50.CrossRef
13.
go back to reference Carella A, Lamberti P, Federico F, Andreula CF. Double fenestration of the extracranial vertebral artery. Neuroradiology. 1978;15:193–4.CrossRef Carella A, Lamberti P, Federico F, Andreula CF. Double fenestration of the extracranial vertebral artery. Neuroradiology. 1978;15:193–4.CrossRef
14.
go back to reference Patel MA, Caplan JM, Yang W, Colby GP, Coon AL, Tamargo RJ, et al. Arterial fenestrations and their association with cerebral aneurysms. J Clin Neurosci. 2014;21:2184–8.CrossRef Patel MA, Caplan JM, Yang W, Colby GP, Coon AL, Tamargo RJ, et al. Arterial fenestrations and their association with cerebral aneurysms. J Clin Neurosci. 2014;21:2184–8.CrossRef
15.
go back to reference Trivelato FP, Abud DG, Nakiri GS, de Castro Afonso LH, Ulhôa AC, Manzato LB, et al. Basilar artery fenestration aneurysms: endovascular treatment strategies based on 3D morphology. Clin Neuroradiol. 2016;26:73–9.CrossRef Trivelato FP, Abud DG, Nakiri GS, de Castro Afonso LH, Ulhôa AC, Manzato LB, et al. Basilar artery fenestration aneurysms: endovascular treatment strategies based on 3D morphology. Clin Neuroradiol. 2016;26:73–9.CrossRef
16.
go back to reference Albanese E, Russo A, Ulm AJ. Fenestrated vertebrobasilar junction aneurysm: diagnostic and therapeutic considerations. J Neurosurg. 2009;110:525–9.CrossRef Albanese E, Russo A, Ulm AJ. Fenestrated vertebrobasilar junction aneurysm: diagnostic and therapeutic considerations. J Neurosurg. 2009;110:525–9.CrossRef
17.
go back to reference Yoon SM, Chun YI, Kwon Y, Kwun BD. Vertebrobasilar junction aneurysms associated with fenestration: experience of five cases treated with Guglielmi detachable coils. Surg Neurol. 2004;61:248–54.CrossRef Yoon SM, Chun YI, Kwon Y, Kwun BD. Vertebrobasilar junction aneurysms associated with fenestration: experience of five cases treated with Guglielmi detachable coils. Surg Neurol. 2004;61:248–54.CrossRef
18.
go back to reference Zhu DY, Fang YB, Wu YN, Li Q, Duan GL, Liu JM, et al. Treatment of fenestrated vertebrobasilar junction-related aneurysms with endovascular techniques. J Clin Neurosci. 2016;28:112–6.CrossRef Zhu DY, Fang YB, Wu YN, Li Q, Duan GL, Liu JM, et al. Treatment of fenestrated vertebrobasilar junction-related aneurysms with endovascular techniques. J Clin Neurosci. 2016;28:112–6.CrossRef
19.
go back to reference Chen CJ, Tseng YC, Lee TH, Hsu HL, See LC. Multisection CT angiography compared with catheter angiography in diagnosing vertebral artery dissection. AJNR Am J Neuroradiol. 2004;25:769–74.PubMed Chen CJ, Tseng YC, Lee TH, Hsu HL, See LC. Multisection CT angiography compared with catheter angiography in diagnosing vertebral artery dissection. AJNR Am J Neuroradiol. 2004;25:769–74.PubMed
20.
go back to reference Teasdale E, Zampakis P, Santosh C, Razvi S. Multidetector computed tomography angiography: application in vertebral artery dissection. Ann Indian Acad Neurol. 2011;14:35–41.CrossRef Teasdale E, Zampakis P, Santosh C, Razvi S. Multidetector computed tomography angiography: application in vertebral artery dissection. Ann Indian Acad Neurol. 2011;14:35–41.CrossRef
21.
go back to reference van Rooij SB, Bechan RS, Peluso JP, Sluzewski M, van Rooij WJ. Fenestrations of intracranial arteries. AJNR Am J Neuroradiol. 2015;36:1167–70.CrossRef van Rooij SB, Bechan RS, Peluso JP, Sluzewski M, van Rooij WJ. Fenestrations of intracranial arteries. AJNR Am J Neuroradiol. 2015;36:1167–70.CrossRef
22.
go back to reference Tamrakar K, Bhattarai B, Munakomi S, Chaudhary P. Unusual finding of vertebral artery fenestration in spontaneous deep nuclear hemorrhage. Cureus. 2016;8:e450.PubMedPubMedCentral Tamrakar K, Bhattarai B, Munakomi S, Chaudhary P. Unusual finding of vertebral artery fenestration in spontaneous deep nuclear hemorrhage. Cureus. 2016;8:e450.PubMedPubMedCentral
Metadata
Title
A case of multiple Vertebrobasilar artery fenestration misdiagnosed as vertebral artery dissection
Authors
Feng Wang
Xiaokai Wang
Xiaohua Li
Huifeng Zheng
Zhiyong Zhang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2020
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-020-01642-2

Other articles of this Issue 1/2020

BMC Neurology 1/2020 Go to the issue