Skip to main content
Top
Published in: Digestive Diseases and Sciences 5/2023

07-12-2022 | Aneurysm | Original Article

Upper Gastrointestinal Bleeding Due to a Left Gastric Artery Pseudoaneurysm: A Case Series

Authors: Seokin Kang, Kee Don Choi, Yuri Kim, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung

Published in: Digestive Diseases and Sciences | Issue 5/2023

Login to get access

Abstract

Background

Left gastric artery (LGA) pseudoaneurysm presenting with upper gastrointestinal (UGI) bleeding is rare but fatal, unless treated.

Aims

We aimed to describe the clinical and endoscopic features of patients with UGI bleeding due to LGA pseudoaneurysms.

Methods

We performed a computerized search of our hospital’s de-identified clinical data warehouse to identify patients with UGI bleeding due to an LGA pseudoaneurysm between 2000 and 2020. Patients’ electronic medical records and data on esophagogastroduodenoscopy and digital subtraction angiography were reviewed retrospectively.

Results

Of 26 patients with an LGA pseudoaneurysm, six patients had UGI bleeding related to an LGA pseudoaneurysm. No patients had previous vascular diseases or pancreatitis. One patient had liver cirrhosis and a history of radiofrequency ablation for hepatocellular carcinoma, one had colon cancer, two had undergone abdominal surgeries, one had received chemoradiotherapy for renal cell carcinoma, and one had no intraabdominal diseases. Symptoms were hematemesis in two, hematochezia in the other two, and melena in the remaining two patients. Esophagogastroduodenoscopy showed a pulsating bulge in the ulcer in two and a large Dieulafoy’s lesion-like structure in four patients. All patients achieved hemostasis by angioembolization.

Conclusion

LGA pseudoaneurysm should be suspected in UGI bleeding if a large Dieulafoy’s lesion-like structure or a pulsating bulge in the ulcer is found at the lesser curvature of the gastric body on endoscopy and if the patient has any intra-abdominal inflammatory disease.
Literature
1.
go back to reference Sakorafas GH, Sarr MG, Farley DR, Que FG, Andrews JC, Farnell MB. Hemosuccus pancreaticus complicating chronic pancreatitis: an obscure cause of upper gastrointestinal bleeding. Langenbecks Arch Surg. 2000;385:124–128.CrossRefPubMed Sakorafas GH, Sarr MG, Farley DR, Que FG, Andrews JC, Farnell MB. Hemosuccus pancreaticus complicating chronic pancreatitis: an obscure cause of upper gastrointestinal bleeding. Langenbecks Arch Surg. 2000;385:124–128.CrossRefPubMed
2.
go back to reference Sessa C, Tinelli G, Porcu P, Aubert A, Thony F, Magne JL. Treatment of visceral artery aneurysms: description of a retrospective series of 42 aneurysms in 34 patients. Ann Vasc Surg. 2004;18:695–703.CrossRefPubMed Sessa C, Tinelli G, Porcu P, Aubert A, Thony F, Magne JL. Treatment of visceral artery aneurysms: description of a retrospective series of 42 aneurysms in 34 patients. Ann Vasc Surg. 2004;18:695–703.CrossRefPubMed
3.
go back to reference Wagner WH, Allins AD, Treiman RL et al. Ruptured visceral artery aneurysms. Ann Vasc Surg. 1997;11:342–347.CrossRefPubMed Wagner WH, Allins AD, Treiman RL et al. Ruptured visceral artery aneurysms. Ann Vasc Surg. 1997;11:342–347.CrossRefPubMed
4.
go back to reference Barrionuevo P, Malas MB, Nejim B et al. A systematic review and meta-analysis of the management of visceral artery aneurysms. J Vasc Surg. 2019;70:1694–1699.CrossRefPubMed Barrionuevo P, Malas MB, Nejim B et al. A systematic review and meta-analysis of the management of visceral artery aneurysms. J Vasc Surg. 2019;70:1694–1699.CrossRefPubMed
5.
go back to reference Pasha SF, Gloviczki P, Stanson AW, Kamath PS. Splanchnic artery aneurysms. Mayo Clin Proc. 2007;82:472–479.CrossRefPubMed Pasha SF, Gloviczki P, Stanson AW, Kamath PS. Splanchnic artery aneurysms. Mayo Clin Proc. 2007;82:472–479.CrossRefPubMed
7.
go back to reference Mullady DK, Wang AY, Waschke KA. AGA clinical practice update on endoscopic therapies for non-variceal upper gastrointestinal bleeding: expert review. Gastroenterology. 2020;159:1120–1128.CrossRefPubMed Mullady DK, Wang AY, Waschke KA. AGA clinical practice update on endoscopic therapies for non-variceal upper gastrointestinal bleeding: expert review. Gastroenterology. 2020;159:1120–1128.CrossRefPubMed
8.
go back to reference Laine L, Barkun AN, Saltzman JR, Martel M, Leontiadis GI. ACG clinical guideline: upper gastrointestinal and ulcer bleeding. Am J Gastroenterol. 2021;116:899–917.CrossRefPubMed Laine L, Barkun AN, Saltzman JR, Martel M, Leontiadis GI. ACG clinical guideline: upper gastrointestinal and ulcer bleeding. Am J Gastroenterol. 2021;116:899–917.CrossRefPubMed
9.
go back to reference Barkun AN, Almadi M, Kuipers EJ et al. Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the International Consensus Group. Ann Intern Med. 2019;171:805–822.CrossRefPubMedPubMedCentral Barkun AN, Almadi M, Kuipers EJ et al. Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the International Consensus Group. Ann Intern Med. 2019;171:805–822.CrossRefPubMedPubMedCentral
10.
go back to reference Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000;356:1318–1321.CrossRefPubMed Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000;356:1318–1321.CrossRefPubMed
11.
go back to reference Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007;25:774–779.CrossRefPubMed Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007;25:774–779.CrossRefPubMed
12.
go back to reference Lim LG, Ho KY, Chan YH et al. Urgent endoscopy is associated with lower mortality in high-risk but not low-risk nonvariceal upper gastrointestinal bleeding. Endoscopy. 2011;43:300–306.CrossRefPubMed Lim LG, Ho KY, Chan YH et al. Urgent endoscopy is associated with lower mortality in high-risk but not low-risk nonvariceal upper gastrointestinal bleeding. Endoscopy. 2011;43:300–306.CrossRefPubMed
13.
go back to reference Chaer RA, Abularrage CJ, Coleman DM et al. The Society for Vascular Surgery clinical practice guidelines on the management of visceral aneurysms. J Vasc Surg. 2020;72:3S-39S.CrossRefPubMed Chaer RA, Abularrage CJ, Coleman DM et al. The Society for Vascular Surgery clinical practice guidelines on the management of visceral aneurysms. J Vasc Surg. 2020;72:3S-39S.CrossRefPubMed
14.
go back to reference Wang TKM, Desai MY. Optimal surveillance and treatment of renal and splenic artery aneurysms. Cleve Clin J Med. 2020;87:755–758.CrossRefPubMed Wang TKM, Desai MY. Optimal surveillance and treatment of renal and splenic artery aneurysms. Cleve Clin J Med. 2020;87:755–758.CrossRefPubMed
15.
go back to reference Valluru B, Yang B, Sharma K et al. Significance of radiology in the diagnosis and management of ruptured left gastric artery aneurysm associated with acute pancreatitis: case report. Medicine (Baltimore). 2019;98:e14824.CrossRefPubMedPubMedCentral Valluru B, Yang B, Sharma K et al. Significance of radiology in the diagnosis and management of ruptured left gastric artery aneurysm associated with acute pancreatitis: case report. Medicine (Baltimore). 2019;98:e14824.CrossRefPubMedPubMedCentral
16.
go back to reference Falodia S, Garg PK, Bhatia V, Ramachandran V, Dash NR, Srivastava DN. EUS diagnosis of a left gastric artery pseudoaneurysm and aneurysmogastric fistula seen with a massive GI hemorrhage (with video). Gastrointest Endosc. 2008;68:389–391.CrossRefPubMed Falodia S, Garg PK, Bhatia V, Ramachandran V, Dash NR, Srivastava DN. EUS diagnosis of a left gastric artery pseudoaneurysm and aneurysmogastric fistula seen with a massive GI hemorrhage (with video). Gastrointest Endosc. 2008;68:389–391.CrossRefPubMed
17.
18.
go back to reference Maharshi S, Sharma SS, Sharma D, Sapra B, Nijhawan S. Endoscopic ultrasound-guided thrombin injection, a management approach for visceral artery pseudoaneurysms. Endosc Int Open. 2020;8:E407-e412.CrossRefPubMedPubMedCentral Maharshi S, Sharma SS, Sharma D, Sapra B, Nijhawan S. Endoscopic ultrasound-guided thrombin injection, a management approach for visceral artery pseudoaneurysms. Endosc Int Open. 2020;8:E407-e412.CrossRefPubMedPubMedCentral
19.
go back to reference Rai P, Kc H, Goel A, Aggarwal R, Sharma M. Endoscopic ultrasound-guided coil and glue for treatment of splenic artery pseudo-aneurysm: new kid on the block! Endosc Int Open. 2018;6:E821-e825.CrossRefPubMedPubMedCentral Rai P, Kc H, Goel A, Aggarwal R, Sharma M. Endoscopic ultrasound-guided coil and glue for treatment of splenic artery pseudo-aneurysm: new kid on the block! Endosc Int Open. 2018;6:E821-e825.CrossRefPubMedPubMedCentral
20.
go back to reference Hashimoto Y, Ohno I, Takahashi H et al. EUS-guided n-butyl-2-cyanoacrylate injection therapy for ruptured isolated left gastric artery pseudoaneurysm. Endosc Ultrasound. 2019;8:58–59.CrossRefPubMed Hashimoto Y, Ohno I, Takahashi H et al. EUS-guided n-butyl-2-cyanoacrylate injection therapy for ruptured isolated left gastric artery pseudoaneurysm. Endosc Ultrasound. 2019;8:58–59.CrossRefPubMed
21.
go back to reference Nagarajan K, Sunilkumar D, Ramakrishnaiah VPN, Amuthabarathi M. Left gastric pseudoaneurysm in a case of chronic pancreatitis: a case report with review of literature. Vasc Endovasc Surg. 2021;55:73–76.CrossRef Nagarajan K, Sunilkumar D, Ramakrishnaiah VPN, Amuthabarathi M. Left gastric pseudoaneurysm in a case of chronic pancreatitis: a case report with review of literature. Vasc Endovasc Surg. 2021;55:73–76.CrossRef
22.
go back to reference Yang PJ, Tsai IT, Huang YC. An uncommon cause of melena—left gastric artery pseudoaneurysm. QJM. 2016;109:133–134.CrossRefPubMed Yang PJ, Tsai IT, Huang YC. An uncommon cause of melena—left gastric artery pseudoaneurysm. QJM. 2016;109:133–134.CrossRefPubMed
23.
go back to reference Pattanshetty D, Bhat P. Left gastric artery pseudoaneurysm as a sequelae of chronic pancreatitis: recognizing a life-threatening complication. Open Med. (Wars) 2014;9:370–373.CrossRef Pattanshetty D, Bhat P. Left gastric artery pseudoaneurysm as a sequelae of chronic pancreatitis: recognizing a life-threatening complication. Open Med. (Wars) 2014;9:370–373.CrossRef
24.
go back to reference Marilley M, Prabhukhot R, Astin M, Chiang K. Left gastric pseudoaneurysmal hemorrhage: a rare endoscopic detection. Gastrointest Endosc. 2010;71:871–873.CrossRefPubMed Marilley M, Prabhukhot R, Astin M, Chiang K. Left gastric pseudoaneurysmal hemorrhage: a rare endoscopic detection. Gastrointest Endosc. 2010;71:871–873.CrossRefPubMed
25.
go back to reference Smith RE, Fontanez-Garcia D, Plavsic BM. Gastrointestinal case of the day. Pseudoaneurysm of the left gastric artery as a complication of acute pancreatitis. Radiographics. 1999;19:1390–1392.CrossRefPubMed Smith RE, Fontanez-Garcia D, Plavsic BM. Gastrointestinal case of the day. Pseudoaneurysm of the left gastric artery as a complication of acute pancreatitis. Radiographics. 1999;19:1390–1392.CrossRefPubMed
26.
go back to reference Noh D, Mun YS. Post-traumatic pseudoaneurysms of the left gastric artery: a case report. Trauma Case Rep. 2019;19:1–6.CrossRefPubMed Noh D, Mun YS. Post-traumatic pseudoaneurysms of the left gastric artery: a case report. Trauma Case Rep. 2019;19:1–6.CrossRefPubMed
27.
go back to reference Nissim L, Diven C, Baun A. Embolization of left gastric artery pseudoaneurysm after blunt trauma. Imaging Med. 2017;9:15–17. Nissim L, Diven C, Baun A. Embolization of left gastric artery pseudoaneurysm after blunt trauma. Imaging Med. 2017;9:15–17.
28.
go back to reference Allorto NL, Royston D, Hadley GP. Traumatic false aneurysm of the left gastric artery. Pediatr Surg Int. 2009;25:455–457.CrossRefPubMed Allorto NL, Royston D, Hadley GP. Traumatic false aneurysm of the left gastric artery. Pediatr Surg Int. 2009;25:455–457.CrossRefPubMed
29.
go back to reference Varela JE, Salzman SL, Owens C, Doherty JC, Fishman D, Merlotti G. Angiographic embolization of a left gastric artery pseudoaneurysm after blunt abdominal trauma. J Trauma. 2006;60:1350–1352.CrossRefPubMed Varela JE, Salzman SL, Owens C, Doherty JC, Fishman D, Merlotti G. Angiographic embolization of a left gastric artery pseudoaneurysm after blunt abdominal trauma. J Trauma. 2006;60:1350–1352.CrossRefPubMed
30.
go back to reference Berjawi T, Nasser H, Naccour J, El-Helou E, Kansoun A. Left gastric artery pseudo-aneurysm post sleeve gastrectomy: a case report. Int J Surg Case Rep. 2020;76:183–185.CrossRefPubMedPubMedCentral Berjawi T, Nasser H, Naccour J, El-Helou E, Kansoun A. Left gastric artery pseudo-aneurysm post sleeve gastrectomy: a case report. Int J Surg Case Rep. 2020;76:183–185.CrossRefPubMedPubMedCentral
31.
go back to reference Downes E, Baker K, Buicko JL, Kichler KM, Brickman LH, Lopez-Viego MA. Hematemesis from a left gastric artery pseudoaneurysm secondary to an adjustable laparoscopic gastric band. J Curr Surg. 2014;4:95–98. Downes E, Baker K, Buicko JL, Kichler KM, Brickman LH, Lopez-Viego MA. Hematemesis from a left gastric artery pseudoaneurysm secondary to an adjustable laparoscopic gastric band. J Curr Surg. 2014;4:95–98.
32.
go back to reference Clemens F. False aneurysm associated with gastric ulcer Report of a case. Radiology. 1971;101:85–86.CrossRefPubMed Clemens F. False aneurysm associated with gastric ulcer Report of a case. Radiology. 1971;101:85–86.CrossRefPubMed
33.
go back to reference Honore C, Bruyere PJ, Maweja S, Meunier P, Meurisse M, Defraigne JO. Pseudoaneurysm of the left gastric artery. J Chir. (Paris) 2009;146:413–415.PubMed Honore C, Bruyere PJ, Maweja S, Meunier P, Meurisse M, Defraigne JO. Pseudoaneurysm of the left gastric artery. J Chir. (Paris) 2009;146:413–415.PubMed
34.
go back to reference Sudo G, Tanuma T, Nakase H. Gastric ulcer bleeding due to left gastric artery pseudoaneurysm. Am J Gastroenterol. 2018;113:1281.CrossRefPubMed Sudo G, Tanuma T, Nakase H. Gastric ulcer bleeding due to left gastric artery pseudoaneurysm. Am J Gastroenterol. 2018;113:1281.CrossRefPubMed
35.
go back to reference Pitton MB, Dappa E, Jungmann F et al. Visceral artery aneurysms: incidence, management, and outcome analysis in a tertiary care center over one decade. Eur Radiol. 2015;25:2004–2014.CrossRefPubMedPubMedCentral Pitton MB, Dappa E, Jungmann F et al. Visceral artery aneurysms: incidence, management, and outcome analysis in a tertiary care center over one decade. Eur Radiol. 2015;25:2004–2014.CrossRefPubMedPubMedCentral
36.
go back to reference Syed SM, Moradian S, Ahmed M, Ahmed U, Shaheen S, Stalin V. A benign gastric ulcer eroding into a splenic artery pseudoaneurysm presenting as a massive upper gastrointestinal bleed. J Surg Case Rep. 2014;2014:rju102.CrossRefPubMedPubMedCentral Syed SM, Moradian S, Ahmed M, Ahmed U, Shaheen S, Stalin V. A benign gastric ulcer eroding into a splenic artery pseudoaneurysm presenting as a massive upper gastrointestinal bleed. J Surg Case Rep. 2014;2014:rju102.CrossRefPubMedPubMedCentral
37.
go back to reference Sawicki M, Marlicz W, Czapla N et al. Massive upper gastrointestinal bleeding from a splenic artery pseudoaneurysm caused by a penetrating gastric ulcer: case report and review of literature. Pol J Radiol. 2015;80:384–387.CrossRefPubMedPubMedCentral Sawicki M, Marlicz W, Czapla N et al. Massive upper gastrointestinal bleeding from a splenic artery pseudoaneurysm caused by a penetrating gastric ulcer: case report and review of literature. Pol J Radiol. 2015;80:384–387.CrossRefPubMedPubMedCentral
Metadata
Title
Upper Gastrointestinal Bleeding Due to a Left Gastric Artery Pseudoaneurysm: A Case Series
Authors
Seokin Kang
Kee Don Choi
Yuri Kim
Hee Kyong Na
Jeong Hoon Lee
Ji Yong Ahn
Kee Wook Jung
Do Hoon Kim
Ho June Song
Gin Hyug Lee
Hwoon-Yong Jung
Publication date
07-12-2022
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 5/2023
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-022-07776-2

Other articles of this Issue 5/2023

Digestive Diseases and Sciences 5/2023 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine