Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Acta Neurochirurgica
Published in: Acta Neurochirurgica 11/2020

01-11-2020 | Aneurysm | Case Report - Vascular Neurosurgery - Other

Ruptured cerebral pseudoaneurysm in an adolescent as an early onset of COVID-19 infection: case report

Authors: Dragan Savić, Tarik M. Alsheikh, Ahmad Kh. Alhaj, Lazar Lazovic, Lamya Alsarraf, Petar Bosnjakovic, Waleed Yousef

Published in: Acta Neurochirurgica | Issue 11/2020

Login to get access

Abstract

The clinical manifestations of coronavirus disease 2019 (COVID-19) are non-specific and multi-inflammatory. They vary from mild to severe manifestations that can be life-threatening. The association of SARS-CoV-2 infection and pseudoaneurysm formation or rupture of an already existing aneurysm is still unexplored. Several mechanisms may be involved, including the direct destruction to the artery by the viral infection or through the release of the inflammatory cytokines. We are presenting a case of a 13-year-old girl with a ruptured cerebral pseudoaneurysm of the left middle cerebral artery (M2 segment) with severe intracerebral hemorrhage as the earliest manifestation of COVID-19 infection.
Literature
1.
Al Saiegh F, Ghosh R, Leibold A et al (2020) Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke. J Neurol Neurosurg Psychiatry:jnnp-2020-323522
2.
Al-Olama M, Rashid A, Garozzo D (2020) COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report. Acta Neurochir 162(7):1495–1499CrossRef
3.
Arabi YM, Harthi A, Hussein J et al (2015) Severe neurologic syndrome associated with Middle East respiratory syndrome corona virus (MERS-CoV). Infection. 43(4):495–501CrossRef
4.
Baeesa SS, Bakhaidar M, Almekhlafi MA, Madani TA (2016) Human immunodeficiency virus-associated cerebral aneurysmal vasculopathy: a systematic review. World Neurosurg 87:220–229CrossRef
5.
Beyrouti R, Adams ME, Benjamin L et al (2020) Characteristics of ischaemic stroke associated with COVID-19 [published online ahead of print, 2020 Apr 30]. J Neurol Neurosurg Psychiatry:jnnp-2020-323586
6.
Carod Artal FJ (2016) Clinical management of infectious cerebral vasculitides. Expert Rev Neurother 16(2):205–221CrossRef
7.
Chen Y, Guo Y, Pan Y, Zhao ZJ (2020) Structure analysis of the receptor binding of 2019-nCoV [published online ahead of print, 2020 Feb 17]. Biochem Biophys Res Commun 525(1):135–140CrossRef
8.
Donoghue M, Hsieh F, Baronas E et al (2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 87(5):E1–E9CrossRef
9.
Fang H, Wright IS, Millikan CH (1958) In: a comparison of blood vessels of the brain and peripheral blood vessels. Cerebral vascular diseases. Grune and Stratton, New York, pp 17–22
10.
11.
Hanafi R, Roger PA, Perin B, Kuchcinski G et al (2020) COVID-19 neurologic complication with CNS vasculitis-like pattern. AJNR Am J Neuroradiol
12.
Hung EC, Chim SS, Chan PK et al (2003) Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome. Clin Chem 49(12):2108–2109CrossRef
13.
Katchanov J, Siebert E, Klingebiel R, Endres M (2010) Infectious vasculopathy of intracranial large- and medium-sized vessels in neurological intensive care unit: a clinico-radiological study. Neurocrit Care 12(3):369–374CrossRef
14.
Morassi M, Bagatto D, Cobelli M et al (2020) Stroke in patients with SARS-CoV-2 infection: case series. J Neurol:1–8
15.
Muhammad S, Haasbach E, Kotchourko M et al (2011) Influenza virus infection aggravates stroke outcome. Stroke. 42(3):783–791CrossRef
16.
Muhammad S, Petridis A, Cornelius JF, Hänggi D (2020) Letter to editor: severe brain haemorrhage and concomitant COVID-19 infection: a neurovascular complication of COVID-19. Brain Behav Immun S0889-1591(20):30802–30803
17.
18.
Qin C, Zhou L, Hu Z et al (2020) Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis:ciaa248
19.
Rustemi O, Raneri F, Iannucci G, Volpin L, Segna A (2020, 2020) Aneurysmal subarachnoid hemorrhage in a SARS-CoV-2 positive testing: casual or causal? Br J Neurosurg:1–2
20.
Sweid A, Hammoud B, Bekelis K et al (2020) Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019. Int J Stroke 2020:1747493020937189
21.
Umapathi T, Kor AC, Venketasubramanian N et al (2004) Large artery ischaemic stroke in severe acute respiratory syndrome (SARS). J Neurol 251(10):1227–1231CrossRef
22.
Wilkinson IM (1972) The vertebral artery. Extracranial and intracranial structure. Arch Neurol 27(5):392–396CrossRef
23.
24.
Wu YC, Chen CS, Chan YJ (2020) The outbreak of COVID-19: an overview. J Chin Med Assoc 83(3):217–220CrossRef
25.
Yonekawa Y, Zumofen D, Imhof HG, Roth P, Khan N (2008) Hemorrhagic cerebral dissecting aneurysms: surgical treatments and results. Acta Neurochir Suppl 103:61–69CrossRef
26.
Zulli A, Burrell LM, Buxton BF, Hare DL (2008) ACE2 and AT4R are present in diseased human blood vessels. Eur J Histochem 52(1):39–44CrossRef
Metadata
Title
Ruptured cerebral pseudoaneurysm in an adolescent as an early onset of COVID-19 infection: case report
Authors
Dragan Savić
Tarik M. Alsheikh
Ahmad Kh. Alhaj
Lazar Lazovic
Lamya Alsarraf
Petar Bosnjakovic
Waleed Yousef
Publication date
01-11-2020
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 11/2020
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-020-04510-7

Other articles of this Issue 11/2020

Acta Neurochirurgica 11/2020 Go to the issue

How I Do it - Neurosurgical technique evaluation

How I do it: endoscopic microvascular decompression for glossopharyngeal neuralgia

Original Article - Brain trauma

The impact of hypertonic saline on cerebrovascular reactivity and compensatory reserve in traumatic brain injury: an exploratory analysis

Original Article - Infection

Reduction in the infection rate of cranioplasty with a tailored antibiotic prophylaxis: a nonrandomized study

Original Article - Tumor - Other

Comorbid depression associated with non-routine discharge following craniotomy for low-grade gliomas and benign tumors – a nationwide readmission database analysis

Original Article - Tumor - Other

Clinical features and long-term surgical outcomes of pure spinal epidural cavernous hemangioma—report of 23 cases

Original Article - Spine - Other

Intraspinal epidermoid and dermoid cysts—tumor resection with multimodal intraoperative neurophysiological monitoring and long-term outcome