Skip to main content
Top
Published in: Neurosurgical Review 1/2024

01-12-2024 | Aneurysm | Research

Risk factor analysis of changes in blood flow in the A1 segment of the anterior cerebral artery after flow-diverter coverage of it

Authors: WuLin Ma, Xin Deng, JunFan Chen, XinBin Guo

Published in: Neurosurgical Review | Issue 1/2024

Login to get access

Abstract

Few studies have explored the effect of a flow-diverter device (FD) on blood flow in the A1 segment of the anterior cerebral artery (ACA), after treatment of intracranial aneurysms in the bifurcation region of the internal carotid artery (ICA). The main objective of this article is to investigate the factors that affect A1 blood flow after FD covers the A1 artery. This is a single-center, retrospective study. Data were collected retrospectively from our center, and patients whose FDs were placed for treatment from the terminal of the ICA to the M1 segment were analyzed. A total of 42 patients were included in the study. Immediate post-procedural angiography following device placement revealed decreased blood flow in the A1 of 15 (35.7%) patients and complete occlusion of the A1 segment in 11 (26.2%) patients. During an average follow-up period of 9.8 months, the A1 segment was ultimately occluded in 25 patients (59.5%) and decreased blood flow in 4 patients (9.5%). When using FD to cover the A1 artery for the treatment of intracranial aneurysms, patients with preoperative opening of the anterior communicating artery (AcomA) are more prone to occlusion or decreased blood flow of the A1 artery, compared to patients without opening.
Literature
1.
go back to reference Briganti F, Leone G, Marseglia M et al (2015) Endovascular treatment of cerebral aneurysms using flow-diverter devices: a systematic review. Neuroradiol J 28(4):365–375CrossRefPubMedPubMedCentral Briganti F, Leone G, Marseglia M et al (2015) Endovascular treatment of cerebral aneurysms using flow-diverter devices: a systematic review. Neuroradiol J 28(4):365–375CrossRefPubMedPubMedCentral
2.
go back to reference Briganti F, Leone G, Ugga L et al (2016) Safety and efficacy of flow re-direction endoluminal device (FRED) in the treatment of cerebral aneurysms: a single center experience. Acta Neurochir (Wien) 158(9):1745–1755CrossRefPubMed Briganti F, Leone G, Ugga L et al (2016) Safety and efficacy of flow re-direction endoluminal device (FRED) in the treatment of cerebral aneurysms: a single center experience. Acta Neurochir (Wien) 158(9):1745–1755CrossRefPubMed
3.
go back to reference Briganti F, Leone G, Ugga L et al (2017) Mid-term and long-term follow-up of intracranial aneurysms treated by the p64 Flow Modulation Device: a multicenter experience. J Neurointerv Surg 9(1):70–76CrossRefPubMed Briganti F, Leone G, Ugga L et al (2017) Mid-term and long-term follow-up of intracranial aneurysms treated by the p64 Flow Modulation Device: a multicenter experience. J Neurointerv Surg 9(1):70–76CrossRefPubMed
4.
go back to reference Wakhloo AK, Lylyk P, de Vries J et al (2015) Surpass flow diverter in the treatment of intracranial aneurysms: a prospective multicenter study. AJNR Am J Neuroradiol 36(1):98–107CrossRefPubMedPubMedCentral Wakhloo AK, Lylyk P, de Vries J et al (2015) Surpass flow diverter in the treatment of intracranial aneurysms: a prospective multicenter study. AJNR Am J Neuroradiol 36(1):98–107CrossRefPubMedPubMedCentral
5.
go back to reference Lubicz B, Van der Elst O, Collignon L, Mine B, Alghamdi F (2015) Silk flow-diverter stent for the treatment of intracranial aneurysms: a series of 58 patients with emphasis on long-term results. AJNR Am J Neuroradiol 36(3):542–546CrossRefPubMedPubMedCentral Lubicz B, Van der Elst O, Collignon L, Mine B, Alghamdi F (2015) Silk flow-diverter stent for the treatment of intracranial aneurysms: a series of 58 patients with emphasis on long-term results. AJNR Am J Neuroradiol 36(3):542–546CrossRefPubMedPubMedCentral
6.
go back to reference Augsburger L, Farhat M, Reymond P et al (2009) Effect of flow diverter porosity on intraaneurysmal blood flow. Klin Neuroradiol 19(3):204–214CrossRefPubMed Augsburger L, Farhat M, Reymond P et al (2009) Effect of flow diverter porosity on intraaneurysmal blood flow. Klin Neuroradiol 19(3):204–214CrossRefPubMed
7.
go back to reference Lieber BB, Livescu V, Hopkins LN, Wakhloo AK (2002) Particle image velocimetry assessment of stent design influence on intra-aneurysmal flow. Ann Biomed Eng 30(6):768–777CrossRefPubMed Lieber BB, Livescu V, Hopkins LN, Wakhloo AK (2002) Particle image velocimetry assessment of stent design influence on intra-aneurysmal flow. Ann Biomed Eng 30(6):768–777CrossRefPubMed
8.
go back to reference Trager AL, Sadasivan C, Seong J, Lieber BB (2009) Correlation between angiographic and particle image velocimetry quantifications of flow diverters in an in vitro model of elastase-induced rabbit aneurysms. J Biomech Eng 131(3):034506CrossRefPubMed Trager AL, Sadasivan C, Seong J, Lieber BB (2009) Correlation between angiographic and particle image velocimetry quantifications of flow diverters in an in vitro model of elastase-induced rabbit aneurysms. J Biomech Eng 131(3):034506CrossRefPubMed
9.
go back to reference Gascou G, Lobotesis K, Brunel H et al (2015) Extra-aneurysmal flow modification following Pipeline embolization device implantation: focus on regional branches, perforators, and the parent vessel. AJNR Am J Neuroradiol 36(4):725–731CrossRefPubMedPubMedCentral Gascou G, Lobotesis K, Brunel H et al (2015) Extra-aneurysmal flow modification following Pipeline embolization device implantation: focus on regional branches, perforators, and the parent vessel. AJNR Am J Neuroradiol 36(4):725–731CrossRefPubMedPubMedCentral
10.
go back to reference Hohenstatt S, Arrichiello A, Conte G et al (2020) Branch vessel occlusion in aneurysm treatment with flow diverter stent. Acta Biomed. 91(10-S):e2020003PubMedPubMedCentral Hohenstatt S, Arrichiello A, Conte G et al (2020) Branch vessel occlusion in aneurysm treatment with flow diverter stent. Acta Biomed. 91(10-S):e2020003PubMedPubMedCentral
11.
go back to reference Cagnazzo F, Lefevre PH, Mantilla D et al (2019) Patency of the supraclinoid internal carotid artery branches after flow diversion treatment A meta-analysis. J Neuroradiol 46(1):9–14CrossRefPubMed Cagnazzo F, Lefevre PH, Mantilla D et al (2019) Patency of the supraclinoid internal carotid artery branches after flow diversion treatment A meta-analysis. J Neuroradiol 46(1):9–14CrossRefPubMed
12.
go back to reference Nossek E, Chalif DJ, Levine M, Setton A (2015) Modifying flow in the ACA-ACoA complex: endovascular treatment option for wide-neck internal carotid artery bifurcation aneurysms. J Neurointerv Surg 7(5):351–356CrossRefPubMed Nossek E, Chalif DJ, Levine M, Setton A (2015) Modifying flow in the ACA-ACoA complex: endovascular treatment option for wide-neck internal carotid artery bifurcation aneurysms. J Neurointerv Surg 7(5):351–356CrossRefPubMed
13.
go back to reference O’Kelly CJ, Krings T, Fiorella D, Marotta TR (2010) A novel grading scale for the angiographic assessment of intracranial aneurysms treated using flow diverting stents. Interv Neuroradiol 16(2):133–137CrossRefPubMedPubMedCentral O’Kelly CJ, Krings T, Fiorella D, Marotta TR (2010) A novel grading scale for the angiographic assessment of intracranial aneurysms treated using flow diverting stents. Interv Neuroradiol 16(2):133–137CrossRefPubMedPubMedCentral
14.
go back to reference Cagnazzo F, Ahmed R, Lefevre PH et al (2020) Flow modification on the internal carotid artery bifurcation region and A1 segment after M1-internal carotid artery flow diverter deployment. J Neurointerv Surg 12(12):1226–1230PubMed Cagnazzo F, Ahmed R, Lefevre PH et al (2020) Flow modification on the internal carotid artery bifurcation region and A1 segment after M1-internal carotid artery flow diverter deployment. J Neurointerv Surg 12(12):1226–1230PubMed
15.
go back to reference Nossek E, Chalif DJ, Chakraborty S, Setton A (2014) Modifying flow in the ICA bifurcation: Pipeline deployment from the supraclinoid ICA extending into the M1 segment-clinical and anatomic results. AJNR Am J Neuroradiol Nov-Dec 35(11):2125–2129CrossRef Nossek E, Chalif DJ, Chakraborty S, Setton A (2014) Modifying flow in the ICA bifurcation: Pipeline deployment from the supraclinoid ICA extending into the M1 segment-clinical and anatomic results. AJNR Am J Neuroradiol Nov-Dec 35(11):2125–2129CrossRef
16.
go back to reference Reymond P, Bohraus Y, Perren F, Lazeyras F, Stergiopulos N (2011) Validation of a patient-specific one-dimensional model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 301(3):H1173-1182CrossRefPubMed Reymond P, Bohraus Y, Perren F, Lazeyras F, Stergiopulos N (2011) Validation of a patient-specific one-dimensional model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 301(3):H1173-1182CrossRefPubMed
17.
go back to reference Fiorella D, Lylyk P, Szikora I et al (2018) Curative cerebrovascular reconstruction with the Pipeline embolization device: the emergence of definitive endovascular therapy for intracranial aneurysms. J Neurointerv Surg 10(Suppl 1):i9–i18CrossRefPubMed Fiorella D, Lylyk P, Szikora I et al (2018) Curative cerebrovascular reconstruction with the Pipeline embolization device: the emergence of definitive endovascular therapy for intracranial aneurysms. J Neurointerv Surg 10(Suppl 1):i9–i18CrossRefPubMed
18.
go back to reference Brinjikji W, Lanzino G, Cloft HJ, Kallmes DF (2014) Patency of the posterior communicating artery after flow diversion treatment of internal carotid artery aneurysms. Clin Neurol Neurosurg 120:84–88CrossRefPubMed Brinjikji W, Lanzino G, Cloft HJ, Kallmes DF (2014) Patency of the posterior communicating artery after flow diversion treatment of internal carotid artery aneurysms. Clin Neurol Neurosurg 120:84–88CrossRefPubMed
19.
go back to reference Vedantam A, Rao VY, Shaltoni HM, Mawad ME (2015) Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the Pipeline embolization device. Neurosurgery 76(2):173–178CrossRefPubMed Vedantam A, Rao VY, Shaltoni HM, Mawad ME (2015) Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the Pipeline embolization device. Neurosurgery 76(2):173–178CrossRefPubMed
20.
go back to reference Lopes DK, Ringer AJ, Boulos AS et al (2003) Fate of branch arteries after intracranial stenting. Neurosurgery 52(6):1275–1278CrossRefPubMed Lopes DK, Ringer AJ, Boulos AS et al (2003) Fate of branch arteries after intracranial stenting. Neurosurgery 52(6):1275–1278CrossRefPubMed
21.
go back to reference Wakhloo AK, Tio FO, Lieber BB, Schellhammer F, Graf M, Hopkins LN (1995) Self-expanding nitinol stents in canine vertebral arteries: hemodynamics and tissue response. AJNR Am J Neuroradiol 16(5):1043–1051PubMedPubMedCentral Wakhloo AK, Tio FO, Lieber BB, Schellhammer F, Graf M, Hopkins LN (1995) Self-expanding nitinol stents in canine vertebral arteries: hemodynamics and tissue response. AJNR Am J Neuroradiol 16(5):1043–1051PubMedPubMedCentral
22.
go back to reference Kallmes DF, Ding YH, Dai D, Kadirvel R, Lewis DA, Cloft HJ (2007) A new endoluminal, flow-disrupting device for treatment of saccular aneurysms. Stroke 38(8):2346–2352CrossRefPubMed Kallmes DF, Ding YH, Dai D, Kadirvel R, Lewis DA, Cloft HJ (2007) A new endoluminal, flow-disrupting device for treatment of saccular aneurysms. Stroke 38(8):2346–2352CrossRefPubMed
23.
go back to reference Pistocchi S, Blanc R, Bartolini B, Piotin M (2012) Flow diverters at and beyond the level of the circle of willis for the treatment of intracranial aneurysms. Stroke 43(4):1032–1038CrossRefPubMed Pistocchi S, Blanc R, Bartolini B, Piotin M (2012) Flow diverters at and beyond the level of the circle of willis for the treatment of intracranial aneurysms. Stroke 43(4):1032–1038CrossRefPubMed
24.
go back to reference Saleme S, Iosif C, Ponomarjova S et al (2014) Flow-diverting stents for intracranial bifurcation aneurysm treatment. Neurosurgery. 75(6):623–631CrossRefPubMed Saleme S, Iosif C, Ponomarjova S et al (2014) Flow-diverting stents for intracranial bifurcation aneurysm treatment. Neurosurgery. 75(6):623–631CrossRefPubMed
Metadata
Title
Risk factor analysis of changes in blood flow in the A1 segment of the anterior cerebral artery after flow-diverter coverage of it
Authors
WuLin Ma
Xin Deng
JunFan Chen
XinBin Guo
Publication date
01-12-2024
Publisher
Springer Berlin Heidelberg
Keywords
Aneurysm
Aneurysm
Published in
Neurosurgical Review / Issue 1/2024
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-024-02306-2

Other articles of this Issue 1/2024

Neurosurgical Review 1/2024 Go to the issue