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Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Published in:

01-03-2010 | Case Reports/Case Series

Anesthesia and myotonic dystrophy type 2: a case series

Authors: Toby N. Weingarten, MD, Ryan E. Hofer, MMS, Margherita Milone, MD, PhD, Juraj Sprung, MD, PhD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 3/2010

Abstract

Background

Myotonic dystrophy type 2 (DM2) is a genetically distinct disorder that shares some phenotypical features of myotonic dystrophy type 1 (DM1). However, anesthetic management of patients with DM2 has not been described. The purpose of this study is to report the anesthetic management of a series of patients with DM2 and to describe their response to anesthesia.

Methods

We performed a computerized search of the Mayo Clinic medical records database looking for patients with DM2 who underwent general anesthesia. The medical records were reviewed for anesthetic technique, medications used, and postoperative complications.

Results

We identified 19 patients with DM2 who underwent 39 general anesthetics, 17 monitored anesthetic care cases, and two regional anesthetics. The patients exhibited normal responses to succinylcholine, nondepolarizing neuromuscular blockers, neostigmine, induction agents, and volatile anesthetics. Serious postoperative complications related to DM2 did not occur.

Conclusion

In our series, patients with DM2 tolerated commonly used anesthetics without obvious complications, and they exhibited normal responses to muscle relaxants. These observations suggest that these medications may be used safely in patients with DM2.

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Title: Anesthesia and myotonic dystrophy type 2: a case series
Authors: Toby N. Weingarten, MD
Ryan E. Hofer, MMS
Margherita Milone, MD, PhD
Juraj Sprung, MD, PhD
Publication date: 01-03-2010
Publisher: Springer-Verlag
Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 3/2010
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI: https://doi.org/10.1007/s12630-009-9244-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Anesthesia and myotonic dystrophy type 2: a case series

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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