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Published in: European Journal of Pediatrics 7/2006

01-07-2006 | Original Paper

ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil

Authors: Farah Thabet, Rim Sghiri, Brahim Tabarki, Ibtissem Ghedira, Moncef Yacoub, Ahmed Sahloul Essoussi

Published in: European Journal of Pediatrics | Issue 7/2006

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Abstract

Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves’s disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage.
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Metadata
Title
ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil
Authors
Farah Thabet
Rim Sghiri
Brahim Tabarki
Ibtissem Ghedira
Moncef Yacoub
Ahmed Sahloul Essoussi
Publication date
01-07-2006
Publisher
Springer-Verlag
Published in
European Journal of Pediatrics / Issue 7/2006
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-005-0053-4

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