Results
All of 15 cases of ULMS showed specific gains and losses. The percentage of average gains and losses were 8.4 and 16.6 %, respectively. The analysis limit of average gains and losses was 40 %. The regions of high level of gain were 1q23.3, 7p14.2, 7q34, 7q35, 7q36.3, 13q34, and 16p13.3. And the regions of homozygous loss were 2q21.1, 2q22.1, 2p23.2, 12q23.3, 4q21.22, 4q34.3, 11q24.2, 12q23.3, 13q13.1, 13q21.33, and 14q24.3. In ULMS samples, recurrent regions of gain were 1p36.33, 1p36.32, 5q35.3, 7q36.3, and 8q24.3 and recurrent regions of loss were 1p31.1–p31.3, 1p32.1–p32.3, 2p12, 2p13.3, 2p14, 2p16.2–p16.3, 2q12.1–q12.3, 2q21.1–q21.2, 2q22.2–q22.3, 2q34, 2q36.1–q36.3, 5q21.3, 5q23.3, 5q31.1, 6p11.2, 6p12.1, 10q11.23, 10q21.2–q21.3, 10q23.2, 10q23.31, 10q25.1–q25.2, 10q25.3, 10q26.13, 10q26.2–q26.3, 11p11.2, 11p11.12, 11p12, 11p13, 11p15.4, 11q23.1–q23.2, 11q23.3, 13q14.12, 13q14.13–13q14.2, 13q14.2, 13q14.2, 13q14.3, 13q21.33, 13q22.1–q22.3, 14q24.2, 14q24.3, 14q31.1, 14q32.33, 15q11.2–q13, 15q14, 16q22.3, 16q23.1, 16q23.2, 16q24.1, 20p12.1, and 21q22.3. Representative frequently gained BAC clones encoded genes were HDAC9, CRR9, SOX18, PTPRN2, SKI, SOLH, and KIAA1199. The genes encoded by frequently lost BAC clones were LOC150516 and AMY2A. A subset of cellular processes from each gene were clustered by Gene Ontology database.