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Virology Journal
Published in: Virology Journal 1/2011

Open Access 01-12-2011 | Research

Analysis of chicken anemia virus genome: evidence of intersubtype recombination

Authors: Yassir M Eltahir, Kun Qian, Wenjie Jin, Aijian Qin

Published in: Virology Journal | Issue 1/2011

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Abstract

Background

Chicken anemia virus (CAV) is the causative agent of chicken infectious anemia. CAV putative intergenotypic recombinants have been reported previously. This fact is based on the previous classification of CAV sequences into three genotypes. However, it is unknown whether intersubtype recombination occurs between the recently reported four CAV genotypes and five subtypes of genome sequences.

Results

Phylogenetic analysis, together with a variety of computational recombination detection algorithms, was used to investigate CAV approximately full genomes. Statistically significant evidence of intersubtype recombination was detected in the parent-like and two putative CAV recombinant sequences. This event was shown to occur between CAV subgroup A1 and A2 sequences in the phylogenetic trees.

Conclusions

We revealed that intersubtype recombination in CAV genome sequences played a role in generating genetic diversity within the natural population of CAV.
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Metadata
Title
Analysis of chicken anemia virus genome: evidence of intersubtype recombination
Authors
Yassir M Eltahir
Kun Qian
Wenjie Jin
Aijian Qin
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2011
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-8-512

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