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Published in: Inflammopharmacology 4/2023

10-04-2023 | Anakinra | Commentary

Anakinra for the prophylaxis of venous thromboembolism in patients with COVID-19

Authors: Chia Siang Kow, Dinesh Sangarran Ramachandram, Syed Shahzad Hasan

Published in: Inflammopharmacology | Issue 4/2023

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Excerpt

Bektaş et al. (2023), in a retrospective observational study, investigated the effect of high-dose intravenous anakinra on the clinical outcomes in patients with severe and critically ill coronavirus disease 2019 (COVID-19), compared to the standard of care. Expectedly, after propensity score matching of two groups of participants, the use of high-dose intravenous anakinra was associated with reduced admission into the intensive care unit (14.1% versus 30.8%) and reduced mortality (14.1% versus 32.1%), compared to standard of care. Furthermore, the reduced mortality with high-dose intravenous anakinra compared with standard of care was also apparent after adjustment of covariates in the multivariate analysis. …
Literature
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Metadata
Title
Anakinra for the prophylaxis of venous thromboembolism in patients with COVID-19
Authors
Chia Siang Kow
Dinesh Sangarran Ramachandram
Syed Shahzad Hasan
Publication date
10-04-2023
Publisher
Springer International Publishing
Published in
Inflammopharmacology / Issue 4/2023
Print ISSN: 0925-4692
Electronic ISSN: 1568-5608
DOI
https://doi.org/10.1007/s10787-023-01203-2

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