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Published in: Reactions Weekly 1/2015

01-04-2015 | News item

Amiodarone + Harvoni, Sovaldi: symptomatic bradycardia

Published in: Reactions Weekly | Issue 1/2015

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Excerpt

Cases of symptomatic bradycardia have been reported in patients receiving amiodarone concurrently with ledipasvir/sofosbuvir (Harvoni) or with sofosbuvir (Sovaldi) in combination with another direct-acting antiviral (DDA)1, warns Gilead Sciences in a "Dear Health Care Provider" letter. …
Footnotes
1
daclatasvir or simeprevir (Olysio)
 
Literature
go back to reference Gilead Sciences. Serious and Life-Threatening Cases of Symptomatic Bradycardia as well as One Case of Fatal Cardiac Arrest Reported with Coadministration of Amiodarone With Either Harvoni (ledipasvir and sofosbuvir fixed-dose combination) or With Sovaldi (sofosbuvir) in Combination with Another Direct Acting Antiviral. Internet Document : 20 Mar 2015. Available from: URL: http://freepdfhosting.com/47b90580b3.pdf Gilead Sciences. Serious and Life-Threatening Cases of Symptomatic Bradycardia as well as One Case of Fatal Cardiac Arrest Reported with Coadministration of Amiodarone With Either Harvoni (ledipasvir and sofosbuvir fixed-dose combination) or With Sovaldi (sofosbuvir) in Combination with Another Direct Acting Antiviral. Internet Document : 20 Mar 2015. Available from: URL: http://​freepdfhosting.​com/​47b90580b3.​pdf
Metadata
Title
Amiodarone + Harvoni, Sovaldi: symptomatic bradycardia
Publication date
01-04-2015
Publisher
Springer International Publishing
Published in
Reactions Weekly / Issue 1/2015
Print ISSN: 0114-9954
Electronic ISSN: 1179-2051
DOI
https://doi.org/10.1007/s40278-015-9093-3

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