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Published in: Critical Care 1/2009

01-03-2009 | Poster presentation

Alveolar wall disruption and lung inflammation associated with positive end-expiratory pressure and recruitment maneuver in pigs

Authors: A Ambrósio, DT Fantoni, CK Marumo, D Otsuki, C Gutierres, Q Lu, J Noel-Morgan, JJ Rouby, JO Auler Jr

Published in: Critical Care | Special Issue 1/2009

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Excerpt

Different levels of positive end-expiratory pressure (PEEP) associated or not with alveolar recruitment maneuver (ARM) may have a significant impact on ventilator-induced lung injury [1], but this issue has not been well addressed in a model of lung injury using inhaled hydrochloric acid. We aimed to evaluate the effects of PEEP and ARM on respiratory mechanics and lung tissue in an inhaled hydrochloric acid acute lung injury (ALI) model. …
Literature
1.
go back to reference Halter JM, Steinberg JM, Schiller HJ, DaSilva M, Gatto LA, Landas S, Nieman GF: Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med 2003, 167: 1620-1626. 10.1164/rccm.200205-435OCCrossRef Halter JM, Steinberg JM, Schiller HJ, DaSilva M, Gatto LA, Landas S, Nieman GF: Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med 2003, 167: 1620-1626. 10.1164/rccm.200205-435OCCrossRef
Metadata
Title
Alveolar wall disruption and lung inflammation associated with positive end-expiratory pressure and recruitment maneuver in pigs
Authors
A Ambrósio
DT Fantoni
CK Marumo
D Otsuki
C Gutierres
Q Lu
J Noel-Morgan
JJ Rouby
JO Auler Jr
Publication date
01-03-2009
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2009
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc7205

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