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Published in: Pediatric Nephrology 6/2005

01-06-2005 | Editorial Commentary

Alterations of leptin and ghrelin serum concentrations in renal disease: simple epiphenomena?

Authors: Jörg Dötsch, Kai Nüsken, Michael Schroth, Wolfgang Rascher, Udo Meißner

Published in: Pediatric Nephrology | Issue 6/2005

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Abstract

The hypothesis that alterations of serum concentrations of the anorexigenic adipose tissue-derived hormone leptin or the orexigenic peptide ghrelin might help to regain appetite and fight malnutrition in patients with chronic renal failure cannot be confirmed at present. For the future, however, strategies interfering with signal transduction of these peptides in the hypothalamus might be more promising and should be investigated and further developed.
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Metadata
Title
Alterations of leptin and ghrelin serum concentrations in renal disease: simple epiphenomena?
Authors
Jörg Dötsch
Kai Nüsken
Michael Schroth
Wolfgang Rascher
Udo Meißner
Publication date
01-06-2005
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 6/2005
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-005-1908-7

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