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Open Access 01-12-2014 | Research article

Alterations in circadian/seasonal rhythms and vegetative functions are related to suicidality in DSM-5 PTSD

Authors: Liliana Dell’Osso, Gabriele Massimetti, Ciro Conversano, Carlo Antonio Bertelloni, Mauro Giovanni Carta, Valdo Ricca, Claudia Carmassi

Published in: BMC Psychiatry | Issue 1/2014

Abstract

Background

Alterations in rhythmicity and vegetative functions have been reported as correlates of suicidality, particularly in patients with mood disorders. No investigation has addressed their impact on patients with post-traumatic stress disorder (PTSD). Aim of the present study was to fulfill this gap.

Methods

Sixty-five out- and inpatients with DSM-5 PTSD were assessed by using the Mood Spectrum-Self Report-Lifetime Version (MOODS-SR), a questionnaire for lifetime mood spectrum symptomatology including alterations in circadian/seasonal rhythms and vegetative functions. Six items of the MOODS-SR were combined and dichotomized to assess suicidal ideation and/or attempts.

Results

Significant and positive associations were found between symptoms of lifetime dysregulations in rhythmicity and vegetative functions and suicidal ideation and/or attempts. All MOODS-SR sub-domains (rhythmicity, sleep, appetite/weight, sexual function, physical symptoms) were associated with an increased likelihood of suicidal ideation, but only changes in appetite/weight were associated with greater odd ratios of suicide attempts (OR = 2.099, 95% CI 1.148-3.841).

Conclusions

Our results suggest that lifetime dysregulations in rhythmicity and vegetative functions may represent correlates of suicidality in patients with DSM-5 PTSD.

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Title: Alterations in circadian/seasonal rhythms and vegetative functions are related to suicidality in DSM-5 PTSD
Authors: Liliana Dell’Osso
Gabriele Massimetti
Ciro Conversano
Carlo Antonio Bertelloni
Mauro Giovanni Carta
Valdo Ricca
Claudia Carmassi
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: BMC Psychiatry / Issue 1/2014
Electronic ISSN: 1471-244X
DOI: https://doi.org/10.1186/s12888-014-0352-2

At a glance: The STEP trials

Springer Medicine

Alterations in circadian/seasonal rhythms and vegetative functions are related to suicidality in DSM-5 PTSD

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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