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Clinical Neuroradiology
Published in: Clinical Neuroradiology 2/2015

01-06-2015 | Correspondence

ALK Positive Anaplastic Large Cell Lymphoma With Pure Leptomeningeal Involvement: Unique Case Report and Review of the Literature

Authors: P. C. Bricker, W. S. Lesley, MD, CPE, FACR, R. Surapaneni, MD

Published in: Clinical Neuroradiology | Issue 2/2015

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Excerpt

Both primary and secondary anaplastic large cell lymphoma (ALCL) involvement of the central nervous system (CNS) is rarely encountered. ALCL is characterized by CD30-positive cells and subclassified by anaplastic lymphoma kinase reactivity (ALK positive [ALK+] or negative [ALK−] cytogenics). Only 13 patients with ALCL have been reported with spread to the CNS. Of these, only one demonstrated pure leptomeningeal involvement with nonspecified ALK status. The following case report details the first instance of ALK+ ALCL with pure leptomeningeal spread. …
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Metadata
Title
ALK Positive Anaplastic Large Cell Lymphoma With Pure Leptomeningeal Involvement: Unique Case Report and Review of the Literature
Authors
P. C. Bricker
W. S. Lesley, MD, CPE, FACR
R. Surapaneni, MD
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue 2/2015
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-013-0280-4

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