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01-05-2015

Alcohol metabolism is not affected by sleeve gastrectomy

Authors: A. S. Gallo, M. A. Berducci, S. Nijhawan, D. F. Nino, R. C. Broderick, C. R. Harnsberger, S. Lazar, C. Echon, H. F. Fuchs, F. Alvarez, B. J. Sandler, G. Jacobsen, S. Horgan

Published in: Surgical Endoscopy | Issue 5/2015

Abstract

Introduction

It has been published that patients who underwent gastric bypass surgery have impaired alcohol metabolism, predisposing them to higher rates of intoxication and DUI arrests. Yet the impact of laparoscopic sleeve gastrectomy (LSG) on alcohol metabolism and in particular the long-term effects are still unclear. We hypothesized that LSG does not alter alcohol metabolism.

Methods

A prospective cohort study of patients undergoing LSG was evaluated. Blood alcohol concentration (BAC) was extrapolated using a Breathalyzer^®. Alcohol metabolism was evaluated by determining BAC every 5 min after a single dose of alcohol (5 oz. glass of 14 % v/v Malbec wine), until BAC was equal to zero. Subjects were queried about alcohol intoxication symptoms. All parameters were obtained and analyzed preoperatively and at 3 and 12 months postoperatively.

Results

Our study consisted of 10 patients (9 female) with a mean age of 46.6 ± 2.2 years and BMI of 43.5 ± 2.2 kg/m². The mean percentage excess weight loss was 39.5 ± 3.3 at 3 months and 55.6 ± 4.4 at 12 months. Peak BAC at 20 min was not different at 3 months (0.068 ± 0.007, p = 0.77) or at 12 months (0.047 ± 0.008, p = 0.19) when compared to the preoperative assessment (0.059 ± 0.014). In addition, the time to BAC equal to zero was not significantly different between baseline and the follow-up values (preoperative: 70 ± 9 min, 3 months: 95 ± 18 min, and 12 months: 57 ± 8 min, (p > 0.05). Symptoms of intoxication were not significantly different in patients before and after surgery.

Conclusions

Our study suggests that LSG does not alter alcohol metabolism. Patients who undergo LSG do not have higher levels of intoxication following alcohol consumption and are therefore not prone to higher rates of DUI charges than the general public, in contrast to that previously reported following in patients who undergo gastric bypass surgery.

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Title: Alcohol metabolism is not affected by sleeve gastrectomy
Authors: A. S. Gallo
M. A. Berducci
S. Nijhawan
D. F. Nino
R. C. Broderick
C. R. Harnsberger
S. Lazar
C. Echon
H. F. Fuchs
F. Alvarez
B. J. Sandler
G. Jacobsen
S. Horgan
Publication date: 01-05-2015
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 5/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-014-3790-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Alcohol metabolism is not affected by sleeve gastrectomy

Abstract

Introduction

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusions

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