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01-02-2015 | Original Article

Airflow limitation following cardiopulmonary exercise testing and heavy-intensity intermittent exercise in children with cystic fibrosis

Authors: Daniel Stevens, Patrick J. Oades, Craig A. Williams

Published in: European Journal of Pediatrics | Issue 2/2015

Abstract

The clinical importance of exercise testing and training in the healthcare management of young patients with cystic fibrosis (CF) is growing. The aim of the present study was to determine the incidence of airflow limitation following cardiopulmonary exercise testing (CPET) and heavy-intensity intermittent exercise (HIIE) in young patients with CF. Nineteen young patients with CF and respective paired–matched controls performed CPET and HIIE on separate days. Forced expiratory volume in one second (FEV₁) was measured pre- and post each exercise modality. A fall in FEV₁ of 10 % or greater was used to define airflow limitation. The incidence of airflow limitation was significantly greater in the CF group than in the controls following CPET (32 vs. 5 %; p = 0.03); however, no significant difference in the incidence of airflow limitation was shown following HIIE between the CF group and controls (11 vs. 16 %; p = 0.64).

Conclusion: Our data show that the incidence of airflow limitation following CPET in young patients with CF is high. Therefore, clinicians may wish to identify whether young CF patients experience airflow limitation following strenuous exercise, such as CPET, before it is performed. However, HIIE carries a low risk for airflow limitation and may be prescribed as a safe, yet effective exercise modality for young patients with CF.

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Title: Airflow limitation following cardiopulmonary exercise testing and heavy-intensity intermittent exercise in children with cystic fibrosis
Authors: Daniel Stevens
Patrick J. Oades
Craig A. Williams
Publication date: 01-02-2015
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Pediatrics / Issue 2/2015
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-014-2387-2

At a glance: The STEP trials

Springer Medicine

Airflow limitation following cardiopulmonary exercise testing and heavy-intensity intermittent exercise in children with cystic fibrosis

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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