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Child's Nervous System

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01-09-2018 | Case Report

Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature

Authors: Ebru Arhan, Ayşe Serdaroğlu, Tuğba Hirfanoğlu, Gökhan Kurt

Published in: Child's Nervous System | Issue 9/2018

Abstract

Background

We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output.

Objective

A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus.

Conclusion

We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.

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Title: Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature
Authors: Ebru Arhan
Ayşe Serdaroğlu
Tuğba Hirfanoğlu
Gökhan Kurt
Publication date: 01-09-2018
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 9/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-018-3806-x

At a glance: The STEP trials

Springer Medicine

Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature

Abstract

Background

Objective

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Objective

Conclusion

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