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Annals of General Psychiatry
Published in: Annals of General Psychiatry 1/2022

Open Access 01-12-2022 | Mood Disorders | Research

What influences psychological functioning in patients with mood disorders? The role of clinical, sociodemographic, and temperamental characteristics in a naturalistic study

Authors: Matteo Di Vincenzo, Gaia Sampogna, Bianca Della Rocca, Carlotta Brandi, Emiliana Mancuso, Lorenzo Landolfi, Antonio Volpicelli, Arcangelo Di Cerbo, Andrea Fiorillo, Mario Luciano

Published in: Annals of General Psychiatry | Issue 1/2022

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Abstract

Background

The present study aims to assess clinical and psychological correlates of psychological functioning in patients with mood disorders, in a naturalistic setting. In particular, we aimed to describe which sociodemographic, clinical, and temperamental dispositions are more frequently associated with poor psychological functioning, and to describe the association between cognitive and psychological functioning in euthymic patients with major depression and bipolar disorder.

Methods

Inclusion criteria were as follows: (1) diagnosis of major depression, or bipolar disorder type I or II; (2) age between 18 and 65 years; and (3) being in a stable phase of the disorder. Patients’ psychiatric symptoms, quality of life, affective temperaments, and impulsivity were investigated with validated assessment instruments.

Results

166 patients have been recruited, mainly female (55.4%), whose mean age was 47.1 ± 14.2 years. 42.6% of individuals reported a diagnosis of major depression. According to regression analyses, poor cognitive performance (p < 0.05), reduced perceived quality of life (p < .0001), lifetime suicide attempts (p < 0.01), and increased trait-related impulsivity (p <0 .001) strongly correlated with poor psychological functioning. Moreover, cyclothymic and irritable dispositions were also associated with poor social functioning (p < 0.01), whereas hyperthymic affective disposition was associated to a better psychological performance (p < 0.01).

Conclusions

Our results support the evidence that patients with mood disorders should be assessed for psychological functioning and affective dispositions, to identify patients at higher risk to develop worse long-term outcomes and to develop targeted interventions.
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Metadata
Title
What influences psychological functioning in patients with mood disorders? The role of clinical, sociodemographic, and temperamental characteristics in a naturalistic study
Authors
Matteo Di Vincenzo
Gaia Sampogna
Bianca Della Rocca
Carlotta Brandi
Emiliana Mancuso
Lorenzo Landolfi
Antonio Volpicelli
Arcangelo Di Cerbo
Andrea Fiorillo
Mario Luciano
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2022
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/s12991-022-00428-9

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