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BMC Psychiatry
Published in: BMC Psychiatry 1/2019

Open Access 01-12-2019 | Mood Disorders | Research article

Factors associated with a positive depression screen after a miscarriage

Authors: Steve Kyende Mutiso, Alfred Murage, Abraham Mukaindo Mwaniki

Published in: BMC Psychiatry | Issue 1/2019

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Abstract

Introduction

Miscarriages are a common pregnancy complication and positive depression screen after a miscarriage has been shown to be high in our population. Various factors are associated with an increased risk of developing depression after a miscarriage. However, these factors vary across populations studied with no studies existing in our region. We set out to determine the factors associated with a positive depression screen among post-miscarriage women at the Aga Khan University hospital, Nairobi.

Methods

Patients were recruited at the 2 weeks clinic review after a miscarriage in the gynaecological clinics. They were screened using the Edinburgh postnatal depression scale for depression after a miscarriage. Analysis was done using Univariate and multivariate analysis to compare clinical variables between the screen - positive and screen - negative women in order to delineate the potential pattern of association between the two among the study subjects.

Results

Positive depression screen was detected in 34.1% of the patients recruited. Univariate analysis revealed that education level (p = 0.039) and mode of conception (p = 0.005) impacted on the outcome of the depression screen. In multivariate analysis, multiple factors impacted on the depression screen and these included: age (p = 0.009), education level (p = 0.001), gestation at miscarriage (p = 0.04), marital status (p = 0.043), prior miscarriage (p = 0.011) and mode of conception (p = 0.03).

Conclusion

Factors that seem to impact on the positive depression screen include a younger age, low education level, an older gestational age at miscarriage, being single, an assisted mode of conception and prior miscarriage. These factors may be used to triage women after a miscarriage in order to pick up those who may screen positive for depression after a miscarriage.
Literature
1.
Tong S, Kaur A, Walker SP, Bryant V, Onwude JL, Permezel M. Miscarriage risk for asymptomatic women after a normal first-trimester prenatal visit. Obstet Gynecol. 2008;111(3):710–4.CrossRef
2.
Zinaman MJ, Clegg ED, Brown CC, O'Connor J, Selevan SG. Estimates of human fertility and pregnancy loss. Fertil Steril. 1996;65(3):503–9.CrossRef
3.
Coleman PK. Abortion and mental health: quantitative synthesis and analysis of research published 1995-2009. The British journal of psychiatry : the journal of mental science. 2011;199(3):180–6.CrossRef
4.
Bianchi-Demicheli F. Psychiatric and psychological consequences of abortion. Revue medicale suisse. 2007;3(98):401–2 4, 6–7.PubMed
5.
McCarthy FP, Moss-Morris R, Khashan AS, North RA, Baker PN, Dekker G, et al. Previous pregnancy loss has an adverse impact on distress and behaviour in subsequent pregnancy. BJOG : an international journal of obstetrics and gynaecology. 2015;122(13):1757–64.CrossRef
6.
Sham A, Yiu M, Ho W. Psychiatric morbidity following miscarriage in Hong Kong. Gen Hosp Psychiatry. 2010;32(3):284–93.CrossRef
7.
Neugebauer R. Depressive symptoms at two months after miscarriage: interpreting study findings from an epidemiological versus clinical perspective. Depression and anxiety. 2003;17(3):152–61.CrossRef
8.
Mutiso SK, Murage A, Mukaindo AM. Prevalence of positive depression screen among post miscarriage women- a cross sectional study. BMC psychiatry. 2018;18(1):32.CrossRef
9.
Reardon DC, Cougle JR, Rue VM, Shuping MW, Coleman PK, Ney PG. Psychiatric admissions of low-income women following abortion and childbirth. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2003;168(10):1253–6.PubMed
10.
Pedersen W. Abortion and depression: a population-based longitudinal study of young women. Scandinavian journal of public health. 2008;36(4):424–8.CrossRef
11.
Reardon DC, Cougle JR. Depression and unintended pregnancy in the National Longitudinal Survey of youth: a cohort study. BMJ (Clinical research ed). 2002;324(7330):151–2.CrossRef
12.
Rees DI, Sabia JJ. The relationship between abortion and depression: new evidence from the fragile families and child wellbeing study. Med Sci Monit. 2007;13(10):Cr430–6.CrossRef
13.
Freda MC, Devine KS, Semelsberger C. The lived experience of miscarriage after infertility. MCN The American journal of maternal child nursing. 2003;28(1):16–23.CrossRef
14.
Khadija W. Prevalence of Postpartum Depression using the Edinburgh Postpartum Depression scale at the Aga Khan University Hospital, Nairobi Aga Khan University Hospital; 2011.
15.
Pourhoseingholi MA, Vahedi M, Rahimzadeh M. Sample size calculation in medical studies. Gastroenterol Hepatol From Bed To Bench. 2013;6(1):14–7.
16.
Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh postnatal depression scale. The British journal of psychiatry : the journal of mental science. 1987;150:782–6.CrossRef
17.
Rich-Edwards JW, Kleinman K, Abrams A, Harlow BL, McLaughlin TJ, Joffe H, et al. Sociodemographic predictors of antenatal and postpartum depressive symptoms among women in a medical group practice. J Epidemiol Community Health. 2006;60(3):221–7.CrossRef
18.
Brown DR, Ahmed F, Gary LE, Milburn NG. Major depression in a community sample of African Americans. Am J Psychiatry. 1995;152(3):373–8.CrossRef
19.
Huffman CS, Schwartz TA, Swanson KM. Couples and Miscarriage: the influence of gender and reproductive factors on the impact of miscarriage. Women's health issues : official publication of the Jacobs Institute of Women's Health. 2015;25(5):570–8.CrossRef
20.
Gerber-Epstein P, Leichtentritt RD, Benyamini Y. The experience of miscarriage in first pregnancy: the Women's voices. Death Studies. 2008;33(1):1–29.CrossRef
21.
Smith LF, Frost J, Levitas R, Bradley H, Garcia J. Women's experiences of three early miscarriage management options: a qualitative study. The British journal of general practice : the journal of the Royal College of General Practitioners. 2006;56(524):198–205.
Metadata
Title
Factors associated with a positive depression screen after a miscarriage
Authors
Steve Kyende Mutiso
Alfred Murage
Abraham Mukaindo Mwaniki
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2019
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-018-1991-5

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