Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
BMC Geriatrics
Published in: BMC Geriatrics 1/2024

Open Access 01-12-2024 | Mood Disorders | Research

Effects of dual-task resistance exercise on cognition, mood, depression, functional fitness, and activities of daily living in older adults with cognitive impairment: a single-blinded, randomized controlled trial

Authors: Ji-Eun Baek, Sang-Jun Hyeon, May Kim, Hwi-young Cho, Suk-Chan Hahm

Published in: BMC Geriatrics | Issue 1/2024

Login to get access

Abstract

Background

Regular exercise is emphasized for the improvement of functional capacity and independence of older adults. This study aimed to compare the effects of a dual-task resistance exercise program and resistance exercise on cognition, mood, depression, physical function, and activities of daily living (ADL) in older adults with cognitive impairment.

Methods

A total of 44 older adults participated in the study. Participants were randomly allocated to an experimental group (n = 22) performing a dual-task resistance exercise program for cognitive function improvement and a control group (n = 22) performing a resistance exercise program. Both groups performed the exercise for 40 min per session, three times a week, for 6 weeks (18 sessions). Cognition, mood, depression, functional fitness, and ADL were quantified before and after the intervention using the Mini-Mental State Examination (MMSE), profile of mood states (POMS), geriatric depression scale (GDS), senior fitness test (SFT), and Korean version of ADL, respectively.

Results

There was a significant time and group interaction on the MMSE (p = 0.044). There were no significant time and group interactions in the POMS, GDS, SFT, or ADL. Cognitive function (p < 0.001), mood (p < 0.001), depression (p < 0.001), functional fitness (p < 0.001), and ADL (p < 0.001) significantly improved after dual-task resistance exercise, and cognitive function (p < 0.001), mood (p < 0.001), depression (p < 0.001), functional fitness (p < 0.001), and ADL (p < 0.001) significantly improved after resistance exercise.

Conclusions

Dual-task resistance exercise is more effective than resistance exercise in improving cognitive function in older adults with cognitive impairment. Both dual-task resistance exercise and resistance exercise improves mood, depression, functional fitness, and ADL after the intervention. We propose using dual-task resistance exercises for cognitive and physical health management in the older adults with cognitive impairment.

Trial registration

This study was registered with the Clinical Research Information Service (WHO International Clinical Trials Registry Platform) (Registration ID, KCT0005389; Registration date, 09/09/2020).
Literature
1.
Centers for Disease Control and Prevention (CDC). Trends in aging–United States and worldwide. MMWR Morb Mortal Wkly Rep. 2003;52:101–6.
2.
3.
4.
Deary IJ, Corley J, Gow AJ, Harris SE, Houlihan LM, Marioni RE, et al. Age-associated cognitive decline. Br Med Bull. 2009;92:135–52.PubMedCrossRef
5.
6.
Krause-Parello CA, Gulick EE, Basin B. Loneliness, Depression, and physical activity in older adults: the therapeutic role of human–animal interactions. Anthrozoos. 2019;32:239–54.CrossRef
7.
Cordes T, Bischoff LL, Schoene D, Schott N, Voelcker-Rehage C, Meixner C, et al. A multicomponent exercise intervention to improve physical functioning, cognition and psychosocial well-being in elderly nursing home residents: a study protocol of a randomized controlled trial in the PROCARE (prevention and occupational health in long-term care) project. BMC Geriatr. 2019;19:369.PubMedPubMedCentralCrossRef
8.
Wang R, Zhang D, Wang S, Zhao T, Zang Y, Su Y. Limitation on activities of daily living, depressive symptoms and suicidal ideation among nursing home residents: the moderating role of resilience. Geriatr Nurs (Minneap). 2020;41:622–8.CrossRef
9.
Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol Biol Sci Med Sci. 2004;59:M255-263.CrossRef
10.
Buckinx F, Rolland Y, Reginster J-Y, Ricour C, Petermans J, Bruyère O. Burden of frailty in the elderly population: perspectives for a public health challenge. Archives Public Health. 2015;73:19.CrossRef
11.
Paterson DH, Jones GR, Rice CL. Ageing and physical activity: evidence to develop exercise recommendations for older adults. Can J Public Health. 2007;98(Suppl 2):S69-108.PubMed
12.
Rodziewicz-Flis EA, Kawa M, Skrobot WR, Flis DJ, Wilczyńska D, Szaro-Truchan M, et al. The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and cognitive abilities in elderly women. Exp Gerontol. 2022;162:111746.PubMedCrossRef
13.
14.
Herold F, Törpel A, Schega L, Müller NG. Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements – a systematic review. Eur Rev Aging Phys Activity. 2019;16:10.CrossRef
15.
Chang H, Kim K, Jung Y-J, Kato M. Effects of acute high-intensity resistance exercise on cognitive function and oxygenation in prefrontal cortex. J Exerc Nutr Biochem. 2017;21:1–8.CrossRef
16.
Coetsee C, Terblanche E. Cerebral oxygenation during cortical activation: the differential influence of three exercise training modalities. A randomized controlled trial. Eur J Appl Physiol. 2017;117:1617–27.PubMedCrossRef
17.
Hong S-G, Kim J-H, Jun T-W. Effects of 12-week resistance exercise on electroencephalogram patterns and cognitive function in the elderly with mild cognitive impairment: a randomized controlled trial. Clin J Sport Med. 2018;28:500–8.PubMedCrossRef
18.
Tsai C-L, Wang C-H, Pan C-Y, Chen F-C, Huang T-H, Chou F-Y. Executive function and endocrinological responses to acute resistance exercise. Front Behav Neurosci. 2014;8.
19.
20.
Chiaramonte R, Bonfiglio M, Leonforte P, Coltraro GL, Guerrera CS, Vecchio M. Proprioceptive and dual-task training: the key of stroke rehabilitation, a systematic review. J Funct Morphol Kinesiol. 2022;7:53.PubMedPubMedCentralCrossRef
21.
Ghadiri F, Bahmani M, Paulson S, Sadeghi H. Effects of fundamental movement skills based dual-task and dance training on single- and dual-task walking performance in older women with dementia. Geriatr Nurs (Minneap). 2022;45:85–92.CrossRef
22.
Chiaramonte R, Cioni M. Critical spatiotemporal gait parameters for individuals with dementia: a systematic review and meta-analysis. Hong Kong Physiotherapy J. 2021;41:1–14.CrossRef
23.
Abdollahi M, Whitton N, Zand R, Dombovy M, Parnianpour M, Khalaf K, et al. A systematic review of fall risk factors in stroke survivors: towards Improved Assessment platforms and protocols. Front Bioeng Biotechnol. 2022;10:910698.PubMedPubMedCentralCrossRef
24.
Jhaveri S, Romanyk M, Glatt R, Satchidanand N. SMARTfit Dual-Task Exercise improves cognition and physical function in older adults with mild cognitive impairment: results of a community-based pilot study. J Aging Phys Act. 2023;31:621–32.PubMedCrossRef
25.
Jardim NYV, Bento-Torres NVO, Costa VO, Carvalho JPR, Pontes HTS, Tomás AM, et al. Dual-task exercise to improve cognition and functional capacity of healthy older adults. Front Aging Neurosci. 2021;13:13.CrossRef
26.
Raichlen DA, Bharadwaj PK, Nguyen LA, Franchetti MK, Zigman EK, Solorio AR, et al. Effects of simultaneous cognitive and aerobic exercise training on dual-task walking performance in healthy older adults: results from a pilot randomized controlled trial. BMC Geriatr. 2020;20:83.PubMedPubMedCentralCrossRef
27.
Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, et al. A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults. Aging Clin Exp Res. 2018;30:921–5.PubMedCrossRef
28.
Bherer L, Gagnon C, Langeard A, Lussier M, Desjardins-Crépeau L, Berryman N, et al. Synergistic effects of cognitive training and physical exercise on dual-task performance in older adults. J Gerontol Ser B. 2021;76:1533–41.CrossRef
29.
Uysal İ, Başar S, Aysel S, Kalafat D, Büyüksünnetçi AÖ. Aerobic exercise and dual-task training combination is the best combination for improving cognitive status, mobility and physical performance in older adults with mild cognitive impairment. Aging Clin Exp Res. 2022;35:271–81.PubMedCrossRef
30.
Tombaugh TN, McIntyre NJ. The mini-mental state examination: a comprehensive review. J Am Geriatr Soc. 1992;40:922–35.PubMedCrossRef
31.
Montero-Odasso M, Casas A, Hansen KT, Bilski P, Gutmanis I, Wells JL, et al. Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study. J Neuroeng Rehabil. 2009;6: 35.PubMedPubMedCentralCrossRef
32.
Cohen J. Statistical Power Analysis for the behavioral sciences. Routledge; 2013.CrossRef
33.
Boripuntakul S, Kothan S, Methapatara P, Munkhetvit P, Sungkarat S. Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: a pilot study. Phys Occup Ther Geriatr. 2012;30:138–49.CrossRef
34.
Prinz A, Langhans C, Rehfeld K, Partie M, Hökelmann A, Witte K. Effects of Music-based physical training on selected motor and cognitive abilities in seniors with dementia-results of an intervention pilot study. J Geriatr Med Gerontol. 2021;7:7.CrossRef
35.
Kim JM, Shin IS, Yoon JS, Lee HY. Comparison of Diagnostic validities between MMSE-K and K-MMSE for Screening of Dementia. J Korean Neuropsychiatric Association. 2003;42:124–30.CrossRef
36.
Kim EJ, Lee SI, Jeong DU, Shin MS, Yoon IY. Standardization and reliability and validity of the Korean Edition of Profile of Mood States (K-POMS). Sleep Med Psychophysiol. 2003;10:39–51.
37.
Bae JN, Cho MJ. Development of the Korean version of the geriatric depression scale and its short form among elderly psychiatric patients. J Psychosom Res. 2004;57:297–305.PubMedCrossRef
38.
Rikli RE, Jones CJ. Development and validation of a functional fitness test for community-residing older adults. J Aging Phys Act. 1999;7:129–61.CrossRef
39.
Lohne-Seiler H, Kolle E, Anderssen SA, Hansen BH. Musculoskeletal fitness and balance in older individuals (65–85 years) and its association with steps per day: a cross sectional study. BMC Geriatr. 2016;16:6.PubMedPubMedCentralCrossRef
40.
Rose DJ, Jones CJ, Lucchese N. Predicting the probability of falls in community-residing older adults using the 8-foot up-and-go: a new measure of functional mobility. J Aging Phys Act. 2002;10:466–75.CrossRef
41.
Zhao Y, Chung P-K. Differences in functional fitness among older adults with and without risk of falling. Asian Nurs Res (Korean Soc Nurs Sci). 2016;10:51–5.PubMed
42.
Peng H-T, Tien C-W, Lin P-S, Peng H-Y, Song C-Y. Novel mat exergaming to improve the physical performance, cognitive function, and dual-task walking and decrease the fall risk of community-dwelling older adults. Front Psychol. 2020;11:1620.PubMedPubMedCentralCrossRef
43.
Won CW, Rho YG, Kim SY, Cho BR, Lee YS. The validity and reliability of Korean activities of Daily Living(K-ADL) Scale. J Korean Geriatr Soc. 2002;6:98–106.
44.
Dik MG, Deeg DJH, Visser M, Jonker C. Early Life Physical Activity and Cognition at Old Age. J Clin Exp Neuropsychol. 2003;25:643–53.PubMedCrossRef
45.
46.
Choi JH, Kim BR, Han EY, Kim SM. The effect of dual-task training on balance and cognition in patients with subacute post-stroke. Ann Rehabil Med. 2015;39:81.PubMedPubMedCentralCrossRef
47.
Pereira Oliva HN, Mansur Machado FS, Rodrigues VD, Leão LL, Monteiro-Júnior RS. The effect of dual-task training on cognition of people with different clinical conditions: an overview of systematic reviews. IBRO Rep. 2020;9:24–31.PubMedPubMedCentralCrossRef
48.
Maclean LM, Brown LJE, Khadra H, Astell AJ. Observing prioritization effects on cognition and gait: the effect of increased cognitive load on cognitively healthy older adults’ dual-task performance. Gait Posture. 2017;53:139–44.PubMedCrossRef
49.
Elkana O, Louzia-Timen R, Kodesh E, Levy S, Netz Y. The effect of a single training session on cognition and mood in young adults – is there added value of a dual-task over a single-task paradigm? Int J Sport Exerc Psychol. 2022;20:36–56.CrossRef
50.
Tait JL, Duckham RL, Milte CM, Main LC, Daly RM. Influence of sequential vs. simultaneous dual-task exercise training on cognitive function in older adults. Front Aging Neurosci. 2017;9:368.PubMedPubMedCentralCrossRef
51.
Landrigan J-F, Bell T, Crowe M, Clay OJ, Mirman D. Lifting cognition: a meta-analysis of effects of resistance exercise on cognition. Psychol Res. 2020;84:1167–83.PubMedCrossRef
52.
Montero-Odasso M, Verghese J, Beauchet O, Hausdorff JM. Gait and cognition: a complementary approach to understanding brain function and the risk of falling. J Am Geriatr Soc. 2012;60:2127–36.PubMedPubMedCentralCrossRef
53.
Beurskens R, Bock O. Age-related deficits of dual-task walking: a review. Neural Plast. 2012;2012:1–9.CrossRef
54.
Gordon BR, McDowell CP, Hallgren M, Meyer JD, Lyons M, Herring MP. Association of efficacy of resistance exercise training with depressive symptoms. JAMA Psychiat. 2018;75:566.CrossRef
55.
Gordon BR, McDowell CP, Lyons M, Herring MP. The effects of resistance exercise training on anxiety: a meta-analysis and meta-regression analysis of randomized controlled trials. Sports Med. 2017;47:2521–32.PubMedCrossRef
56.
Tsutsumi T, Don BM, Zaichkowsky LD, Delizonna LL. Physical fitness and psychological benefits of strength training in community dwelling older adults. Appl Hum Sci. 1997;16:257–66.CrossRef
57.
Dionigi R. Resistance training and older adults’ beliefs about psychological benefits: the importance of self-efficacy and social interaction. J Sport Exerc Psychol. 2007;29:723–46.PubMedCrossRef
58.
McDermott LM, Ebmeier KP. A meta-analysis of depression severity and cognitive function. J Affect Disord. 2009;119:1–8.PubMedCrossRef
59.
Matsouka O, Kabitsis C, Harahousou Y, Trigonis I. Mood alterations following an indoor and outdoor exercise program in healthy elderly women. Percept Mot Skills. 2005;100:707–15.PubMedCrossRef
60.
Yoshiuchi K, Nakahara R, Kumano H, Kuboki T, Togo F, Watanabe E, et al. Yearlong physical activity and depressive symptoms in older Japanese adults: cross-sectional data from the Nakanojo Study. Am J Geriatric Psychiatry. 2006;14:621–4.CrossRef
61.
Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159:2349–56.PubMedCrossRef
62.
Komatsu H, Yagasaki K, Saito Y, Oguma Y. Regular group exercise contributes to balanced health in older adults in Japan: a qualitative study. BMC Geriatr. 2017;17:190.PubMedPubMedCentralCrossRef
63.
Zimmer C, McDonough MH, Hewson J, Toohey A, Din C, Crocker PRE, et al. Experiences with social participation in group physical activity programs for older adults. J Sport Exerc Psychol. 2021;43:335–44.PubMedCrossRef
64.
Sebastião E, Mirda D. Group-based physical activity as a means to reduce social isolation and loneliness among older adults. Aging Clin Exp Res. 2021;33:2003–6.PubMedCrossRef
65.
Paterson DH, Warburton DE. Physical activity and functional limitations in older adults: a systematic review related to Canada’s Physical Activity guidelines. Int J Behav Nutr Phys Activity. 2010;7:38.CrossRef
66.
67.
Schlosser Covell GE, Hoffman-Snyder CR, Wellik KE, Woodruff BK, Geda YE, Caselli RJ, et al. Physical activity level and future risk of mild cognitive impairment or dementia. Neurologist. 2015;19:89–91.PubMedCrossRef
68.
Liu X, Jiang Y, Peng W, Wang M, Chen X, Li M. Association between physical activity and mild cognitive impairment in community-dwelling older adults: Depression as a mediator. Front Aging Neurosci., Galán-Mercant A, Carnero EA, Fernandes B et al. Functional Capacity and Levels of Physical Activity in Aging: A 3-Year Follow-up. Front Med (Lausanne). 2018;4:964886.
69.
Tomás MT, Galán-Mercant A, Carnero EA, Fernandes B. Functional capacity and levels of physical activity in aging: a 3-Year follow-up. Front Med (Lausanne). 2018;4:244.PubMedCrossRef
70.
Tak E, Kuiper R, Chorus A, Hopman-Rock M. Prevention of onset and progression of basic ADL disability by physical activity in community dwelling older adults: a meta-analysis. Ageing Res Rev. 2013;12:329–38.PubMedCrossRef
71.
Joosten H, van Eersel MEA, Gansevoort RT, Bilo HJG, Slaets JPJ, Izaks GJ. Cardiovascular Risk Profile and cognitive function in young, middle-aged, and elderly subjects. Stroke. 2013;44:1543–9.PubMedCrossRef
72.
Ko H, Jung S. Association of Social Frailty with Physical Health, cognitive function, Psychological Health, and life satisfaction in Community-Dwelling Older koreans. Int J Environ Res Public Health. 2021;18: 818.PubMedPubMedCentralCrossRef
73.
Matthews F, Marioni R, Brayne C. Examining the influence of gender, education, social class and birth cohort on MMSE tracking over time: a population-based prospective cohort study. BMC Geriatr. 2012;12: 45.PubMedPubMedCentralCrossRef
Metadata
Title
Effects of dual-task resistance exercise on cognition, mood, depression, functional fitness, and activities of daily living in older adults with cognitive impairment: a single-blinded, randomized controlled trial
Authors
Ji-Eun Baek
Sang-Jun Hyeon
May Kim
Hwi-young Cho
Suk-Chan Hahm
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2024
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-024-04942-1

Other articles of this Issue 1/2024

BMC Geriatrics 1/2024 Go to the issue

Research

Repeated hospital admission for intentional poisonings among older adults - a Swedish national register-based study

Research

Tailored videoconferencing counselling program to support family carers of people living with dementia during the transition to permanent residential care: a pilot and feasibility randomised trial

Research

An in-person survey of the influence of the COVID-19 pandemic on physical function, functional capacity, cognitive function, and mental health among community-dwelling older adults in Japan from 2016 to 2022

Research

Interaction between hypertension and frailty and their impact on death risk in older adults: a follow-up study

Research

Role of muscle ultrasound in frailty assessment in older adults with type 2 diabetes mellitus

Research

Association of smart elderly care and quality of life among older adults: the mediating role of social support
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Image Credits