Skip to main content
Top
Published in: Journal of Clinical Psychology in Medical Settings 2/2009

01-06-2009

Aerobic Exercise Enhances Cognitive Flexibility

Authors: Steven Masley, Richard Roetzheim, Thomas Gualtieri

Published in: Journal of Clinical Psychology in Medical Settings | Issue 2/2009

Login to get access

Abstract

Introduction Physical activity is believed to prevent cognitive decline and may enhance frontal lobe activity. Methods Subjects were 91 healthy adults enrolled in a wellness center. Over a 10 week intervention, controls were aerobically active 0–2 days per week. Half the intervention group was active 3–4 days/week and half 5–7 days/week. Outcome measures included memory, mental speed, reaction time, attention, and cognitive flexibility. Results Neurocognitive data were analyzed by repeated measures comparing minimal aerobic exercise (the control group) to moderate aerobic exercise (3–4 days/week), and to high aerobic exercise (5–7 days/week). Initial analyses noted significant improvements in mental speed (p = .03), attention (p = .047), and cognitive flexibility (p = .002). After controlling for age, gender, education, and changes in psychomotor speed, only cognitive flexibility still showed significant improvements (p = .02). Conclusion Over a 10 week period, increasing frequency of aerobic activity was shown to be associated with enhanced cognitive performance, in particular cognitive flexibility, a measure of executive function.
Appendix
Available only for authorised users
Literature
go back to reference Baker, E. L., Letz, R. E., Fidler, A. T., Shalat, S., Plantamura, D., & Lyndon, M. (1985). A computer-based neurobehavioral evaluation system for occupational and environmental epidemiology: Methodology and validation studies. Neurobehavioral Toxicology and Teratology, 7, 369–377.PubMed Baker, E. L., Letz, R. E., Fidler, A. T., Shalat, S., Plantamura, D., & Lyndon, M. (1985). A computer-based neurobehavioral evaluation system for occupational and environmental epidemiology: Methodology and validation studies. Neurobehavioral Toxicology and Teratology, 7, 369–377.PubMed
go back to reference Barnes, D. E., Yaffe, K., Satariano, W. A., & Tager, I. B. (2003). A longitudinal study of cardio respiratory fitness and cognitive function in health older adults. Journal of the American Geriatric Society, 51, 459–465.CrossRef Barnes, D. E., Yaffe, K., Satariano, W. A., & Tager, I. B. (2003). A longitudinal study of cardio respiratory fitness and cognitive function in health older adults. Journal of the American Geriatric Society, 51, 459–465.CrossRef
go back to reference Cameron, H. A., & McKay, R. D. (1999). Restoring production of hippocampal neurons in old age. Nature Neuroscience, 2, 894–897.PubMedCrossRef Cameron, H. A., & McKay, R. D. (1999). Restoring production of hippocampal neurons in old age. Nature Neuroscience, 2, 894–897.PubMedCrossRef
go back to reference Churchill, J. D., Galvez, R., Colcombe, S., Swain, R. A., Kramer, A. F., & Greenough, W. T. (2002). Exercise, experience and the aging brain. Neurobiology of Aging, 23, 941–955.PubMedCrossRef Churchill, J. D., Galvez, R., Colcombe, S., Swain, R. A., Kramer, A. F., & Greenough, W. T. (2002). Exercise, experience and the aging brain. Neurobiology of Aging, 23, 941–955.PubMedCrossRef
go back to reference Colcombe, S. J., Erickson, K. I., Raz, N., Webb, A. G., Cohen, N. J., McAuley, E., et al. (2003). Aerobic fitness reduces brain tissue loss in aging humans. Journal of Gerontology, 58, 176–180. Colcombe, S. J., Erickson, K. I., Raz, N., Webb, A. G., Cohen, N. J., McAuley, E., et al. (2003). Aerobic fitness reduces brain tissue loss in aging humans. Journal of Gerontology, 58, 176–180.
go back to reference Colcombe, S. J., & Kramer, A. F. (2003). Fitness effects on cognitive function of older adults: A meta-analytic study. Psychological Science, 14, 125–130.PubMedCrossRef Colcombe, S. J., & Kramer, A. F. (2003). Fitness effects on cognitive function of older adults: A meta-analytic study. Psychological Science, 14, 125–130.PubMedCrossRef
go back to reference Colcombe, S. J., Kramer, A. F., McAuley, E., Erickson, K. I., & Scalf, P. (2004). Neurocognitive aging and cardiovascular fitness. Journal of Molecular Neuroscience, 24, 9–14.PubMedCrossRef Colcombe, S. J., Kramer, A. F., McAuley, E., Erickson, K. I., & Scalf, P. (2004). Neurocognitive aging and cardiovascular fitness. Journal of Molecular Neuroscience, 24, 9–14.PubMedCrossRef
go back to reference Cotman, C. W., & Berchtold, N. C. (2002). Exercise: A behavioural intervention to enhance brain health and plasticity. Trends in Neurosciences, 25, 295–301.PubMedCrossRef Cotman, C. W., & Berchtold, N. C. (2002). Exercise: A behavioural intervention to enhance brain health and plasticity. Trends in Neurosciences, 25, 295–301.PubMedCrossRef
go back to reference Gómez-Pinilla, F., So, V., & Kesslak, J. P. (1998). Spatial learning and physical activity contribute to the induction of fibroblast growth factor: Neural substrates for increased cognition associated with exercise. Neuroscience, 85, 53–61.PubMedCrossRef Gómez-Pinilla, F., So, V., & Kesslak, J. P. (1998). Spatial learning and physical activity contribute to the induction of fibroblast growth factor: Neural substrates for increased cognition associated with exercise. Neuroscience, 85, 53–61.PubMedCrossRef
go back to reference Gualtieri, C. T., & Johnson, L. G. (2006a). Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs. Archives of Clinical Neuropsychology, 21, 623–643.PubMedCrossRef Gualtieri, C. T., & Johnson, L. G. (2006a). Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs. Archives of Clinical Neuropsychology, 21, 623–643.PubMedCrossRef
go back to reference Gualtieri, C. T., & Johnson, L. G. (2006b). A computerized neurocognitive test battery for studies of schizophrenic and bipolar patients. Abstract, 13th biennial winter workshop on schizophrenia research, Davos. Schizophrenia Research, 81, 122. Gualtieri, C. T., & Johnson, L. G. (2006b). A computerized neurocognitive test battery for studies of schizophrenic and bipolar patients. Abstract, 13th biennial winter workshop on schizophrenia research, Davos. Schizophrenia Research, 81, 122.
go back to reference Gualtieri, C. T., & Johnson, L. (2006c). Neurocognitive testing supports a broader concept of mild cognitive impairment. Journal of Alzheimer’s Related Dementia, 20, 359–366. Gualtieri, C. T., & Johnson, L. (2006c). Neurocognitive testing supports a broader concept of mild cognitive impairment. Journal of Alzheimer’s Related Dementia, 20, 359–366.
go back to reference Gualtieri, C. T., Johnson, L., & Benedict, K. B. (2006). Neurocognition in depression: Patients on and off medication versus healthy comparison subjects. Journal of Neuropsychiatry and Clinical Neurosciences, 18, 217–225.PubMed Gualtieri, C. T., Johnson, L., & Benedict, K. B. (2006). Neurocognition in depression: Patients on and off medication versus healthy comparison subjects. Journal of Neuropsychiatry and Clinical Neurosciences, 18, 217–225.PubMed
go back to reference Heyn, P., Abreu, B. C., & Ottenbacher, K. J. (2004). The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis. Archives of Physical Medicine and Rehabilitation, 85, 1694–1704.PubMedCrossRef Heyn, P., Abreu, B. C., & Ottenbacher, K. J. (2004). The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis. Archives of Physical Medicine and Rehabilitation, 85, 1694–1704.PubMedCrossRef
go back to reference Hillman, C. H., Belopolsky, A. V., Snook, E. M., Framer, A. F., & McAuley, E. (2004). Physical activity and executive control: Implications for increased cognitive health during older adulthood. Research Quarterly for Exercise and Sport, 75, 176–185.PubMed Hillman, C. H., Belopolsky, A. V., Snook, E. M., Framer, A. F., & McAuley, E. (2004). Physical activity and executive control: Implications for increased cognitive health during older adulthood. Research Quarterly for Exercise and Sport, 75, 176–185.PubMed
go back to reference Kubesch, S., Bretschneider, V., Freudenmann, R., Weidenhammer, N., Lehmann, M., Spitzer, M., et al. (2003). Aerobic endurance exercise improves executive functions in depressed patients. Journal of Clinical Psychiatry, 64, 1005–1012.PubMedCrossRef Kubesch, S., Bretschneider, V., Freudenmann, R., Weidenhammer, N., Lehmann, M., Spitzer, M., et al. (2003). Aerobic endurance exercise improves executive functions in depressed patients. Journal of Clinical Psychiatry, 64, 1005–1012.PubMedCrossRef
go back to reference Larson, E. B., Wang, L., Bowen, J. D., McCormick, W. C., Teri, L., Crane, P., et al. (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals Internal Medicine, 144, 73–81. Larson, E. B., Wang, L., Bowen, J. D., McCormick, W. C., Teri, L., Crane, P., et al. (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals Internal Medicine, 144, 73–81.
go back to reference Lautenschlager, N. T., & Almeida, O. P. (2006). Physical activity and cognition in old age. Current Opinion in Psychiatry, 19, 190–193.PubMedCrossRef Lautenschlager, N. T., & Almeida, O. P. (2006). Physical activity and cognition in old age. Current Opinion in Psychiatry, 19, 190–193.PubMedCrossRef
go back to reference Lautenschlager, N. T., Cox, K. L., Flicker, L., Foster, J. K., van Bockxmeer, F. M., Xiao, J. G., et al. (2008). Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease. JAMA, 300, 1027–1037.PubMedCrossRef Lautenschlager, N. T., Cox, K. L., Flicker, L., Foster, J. K., van Bockxmeer, F. M., Xiao, J. G., et al. (2008). Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease. JAMA, 300, 1027–1037.PubMedCrossRef
go back to reference Le, T. H., Pardo, J. V., & Hu, X. (1998). 4 T-fMRI study of nonspatial shifting of selective attention: Cerebellar and parietal contributions. Journal of Neurophysiology, 7, 1535–1548. Le, T. H., Pardo, J. V., & Hu, X. (1998). 4 T-fMRI study of nonspatial shifting of selective attention: Cerebellar and parietal contributions. Journal of Neurophysiology, 7, 1535–1548.
go back to reference Manini, T. M., Everhart, J. E., Patel, K. V., Schoeller, D. A., Colber, L. H., Visser, M., et al. (2006). Daily activity energy expenditure and mortality among older adults. JAMA, 296, 171–179.PubMedCrossRef Manini, T. M., Everhart, J. E., Patel, K. V., Schoeller, D. A., Colber, L. H., Visser, M., et al. (2006). Daily activity energy expenditure and mortality among older adults. JAMA, 296, 171–179.PubMedCrossRef
go back to reference Masley, S. C., Weaver, W., Peri, G., & Phillips, S. (2005). Impact of an exercise and dietary program on weight loss. Journal of the American College of Nutrition, 24 (abstract) 431. Masley, S. C., Weaver, W., Peri, G., & Phillips, S. (2005). Impact of an exercise and dietary program on weight loss. Journal of the American College of Nutrition, 24 (abstract) 431.
go back to reference Masley, S. C., Weaver, W., Peri, G., & Phillips, S. (2006). High-fiber, low-saturated fat diet combined with exercise enhances VO2max and lipid profiles. Circulation, 113 (abstract), 380. Masley, S. C., Weaver, W., Peri, G., & Phillips, S. (2006). High-fiber, low-saturated fat diet combined with exercise enhances VO2max and lipid profiles. Circulation, 113 (abstract), 380.
go back to reference Masley, S. C., Weaver, W., Peri, G., & Phillips, S. E. (2008). Efficacy of lifestyle changes in modifying practical markers of wellness and aging. Alternative Therapies in Health and Medicine, 14, 24–31.PubMed Masley, S. C., Weaver, W., Peri, G., & Phillips, S. E. (2008). Efficacy of lifestyle changes in modifying practical markers of wellness and aging. Alternative Therapies in Health and Medicine, 14, 24–31.PubMed
go back to reference Mummery, K., Schofield, G., & Caperchione, C. (2004). Physical activity dose–response effects on mental health status in older adults. Australian and New Zealand Journal of Public Health, 28, 188–192.PubMedCrossRef Mummery, K., Schofield, G., & Caperchione, C. (2004). Physical activity dose–response effects on mental health status in older adults. Australian and New Zealand Journal of Public Health, 28, 188–192.PubMedCrossRef
go back to reference Nagahama, Y., Sadato, N., Yamauchi, H., Katsumi, Y., Hayashi, T., Fukuyama, H., et al. (1998). Neural activity during attention shifts between object features. Neuroreport, 9, 2633–2638.PubMedCrossRef Nagahama, Y., Sadato, N., Yamauchi, H., Katsumi, Y., Hayashi, T., Fukuyama, H., et al. (1998). Neural activity during attention shifts between object features. Neuroreport, 9, 2633–2638.PubMedCrossRef
go back to reference Neeper, S. A., Gomez-Padilla, F., Choi, J., & Cotman, C. (1995). Exercise and brain neurotrophins. Nature, 373, 109.PubMedCrossRef Neeper, S. A., Gomez-Padilla, F., Choi, J., & Cotman, C. (1995). Exercise and brain neurotrophins. Nature, 373, 109.PubMedCrossRef
go back to reference Pierce, T. W., Madden, D. J., Siegel, W. C., & Blumenthal, J. A. (1993). Effects of aerobic exercise on cognitive and psychosocial functioning in patients with mild hypertension. Health Psychology, 12, 286–291.PubMedCrossRef Pierce, T. W., Madden, D. J., Siegel, W. C., & Blumenthal, J. A. (1993). Effects of aerobic exercise on cognitive and psychosocial functioning in patients with mild hypertension. Health Psychology, 12, 286–291.PubMedCrossRef
go back to reference Rey, A. (1964). L’examen clinique en psychologie. Paris: Presses Universitaires de France. Rey, A. (1964). L’examen clinique en psychologie. Paris: Presses Universitaires de France.
go back to reference Rikli, R. E., & Edwards, D. J. (1991). Effects of a three-year exercise program on motor function and cognitive processing speed in older women. Research Quarterly for Exercise and Sport, 62, 61–67.PubMed Rikli, R. E., & Edwards, D. J. (1991). Effects of a three-year exercise program on motor function and cognitive processing speed in older women. Research Quarterly for Exercise and Sport, 62, 61–67.PubMed
go back to reference Rogers, R. L., Meyer, J. S., & Mortel, K. F. (1990). After reaching retirement age physical activity sustains cerebral perfusion and cognition. Journal of the American Geriatric Society, 38, 123–128. Rogers, R. L., Meyer, J. S., & Mortel, K. F. (1990). After reaching retirement age physical activity sustains cerebral perfusion and cognition. Journal of the American Geriatric Society, 38, 123–128.
go back to reference Rosvold, H. E., & Delgado, J. M. (1956). The effect on delayed-alternation test performance of stimulating or destroying electrically structures within the frontal lobes of the monkey’s brain. Journal of Comparative and Physiological Psychology, 49, 365–372.PubMedCrossRef Rosvold, H. E., & Delgado, J. M. (1956). The effect on delayed-alternation test performance of stimulating or destroying electrically structures within the frontal lobes of the monkey’s brain. Journal of Comparative and Physiological Psychology, 49, 365–372.PubMedCrossRef
go back to reference Roth, D. L., Goode, K. T., Clay, O. J., & Ball, K. K. (2003). Association of physical activity and visual attention in older adults. Journal of Aging and Health, 15, 534–547.PubMedCrossRef Roth, D. L., Goode, K. T., Clay, O. J., & Ball, K. K. (2003). Association of physical activity and visual attention in older adults. Journal of Aging and Health, 15, 534–547.PubMedCrossRef
go back to reference Singh-Manoux, A., Hillsdon, M., Brunner, E., & Marmot, M. (2005). Effects of physical activity on cognitive functioning in middle age: Evidence from the Whitehall II Prospective Cohort Study. American Journal of Public Health, 95, 2252–2258.PubMedCrossRef Singh-Manoux, A., Hillsdon, M., Brunner, E., & Marmot, M. (2005). Effects of physical activity on cognitive functioning in middle age: Evidence from the Whitehall II Prospective Cohort Study. American Journal of Public Health, 95, 2252–2258.PubMedCrossRef
go back to reference Small, G. W., Silverman, D. H., Siddarth, P., Ercoli, L. M., Miller, K. R., et al. (2006). Effects of a 14-day healthy longevity lifestyle program on cognition and brain function. American Journal of Geriatric Psychiatry, 14, 538–545.PubMedCrossRef Small, G. W., Silverman, D. H., Siddarth, P., Ercoli, L. M., Miller, K. R., et al. (2006). Effects of a 14-day healthy longevity lifestyle program on cognition and brain function. American Journal of Geriatric Psychiatry, 14, 538–545.PubMedCrossRef
go back to reference Smith, A. (1982). Symbol Digit Modalities Test (SDMT). Manual (Revised). Los Angeles, CA: Western Psychological Services. Smith, A. (1982). Symbol Digit Modalities Test (SDMT). Manual (Revised). Los Angeles, CA: Western Psychological Services.
go back to reference Taddei, S., Galetta, F., Virdis, A., Ghiadoni, L., Salveti, G., Franzoni, F., et al. (2000). Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation, 101, 2896–2901.PubMed Taddei, S., Galetta, F., Virdis, A., Ghiadoni, L., Salveti, G., Franzoni, F., et al. (2000). Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation, 101, 2896–2901.PubMed
go back to reference Taylor, E. M. (1959). The appraisal of children with cerebral deficits. Cambridge, MA: Harvard University Press. Taylor, E. M. (1959). The appraisal of children with cerebral deficits. Cambridge, MA: Harvard University Press.
go back to reference van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999). Running enhances neurogenesis, learning, and longterm potentiation in mice. In Proceedings of the National Academy of Sciences of the United States of America (Vol. 96, pp. 13427–13431). van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999). Running enhances neurogenesis, learning, and longterm potentiation in mice. In Proceedings of the National Academy of Sciences of the United States of America (Vol. 96, pp. 13427–13431).
go back to reference Weuve, J., Kang, J. H., Manson, J. E., Breteler, M. M., Ware, J. H., & Grodstein, F. (2004). Physical activity, including walking, and cognitive function in older women. JAMA, 292, 1454–1461.PubMedCrossRef Weuve, J., Kang, J. H., Manson, J. E., Breteler, M. M., Ware, J. H., & Grodstein, F. (2004). Physical activity, including walking, and cognitive function in older women. JAMA, 292, 1454–1461.PubMedCrossRef
Metadata
Title
Aerobic Exercise Enhances Cognitive Flexibility
Authors
Steven Masley
Richard Roetzheim
Thomas Gualtieri
Publication date
01-06-2009
Publisher
Springer US
Published in
Journal of Clinical Psychology in Medical Settings / Issue 2/2009
Print ISSN: 1068-9583
Electronic ISSN: 1573-3572
DOI
https://doi.org/10.1007/s10880-009-9159-6

Other articles of this Issue 2/2009

Journal of Clinical Psychology in Medical Settings 2/2009 Go to the issue