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Scoliosis and Spinal Disorders
Published in: Scoliosis and Spinal Disorders 1/2016

Open Access 01-12-2016 | Review

Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies

Authors: Marcelo Wajchenberg, Nelson Astur, Michel Kanas, Délio Eulálio Martins

Published in: Scoliosis and Spinal Disorders | Issue 1/2016

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Abstract

Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS.
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Metadata
Title
Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies
Authors
Marcelo Wajchenberg
Nelson Astur
Michel Kanas
Délio Eulálio Martins
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Scoliosis and Spinal Disorders / Issue 1/2016
Electronic ISSN: 2397-1789
DOI
https://doi.org/10.1186/s13013-016-0066-y

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